Zoetis Products for New Pets

Simparica Trio

Use with caution in dogs with a history of seizures. Simparica Trio contains sarolaner, a member of the isoxazoline class which has been associated with neurologic adverse reactions including tremors, ataxia, and seizures in dogs with or without a history of neurologic disorders. The safe use of Simparica Trio has not been evaluated in breeding, pregnant, or lactating dogs. The most frequently reported adverse reactions in clinical trials were vomiting and diarrhea. See full Prescribing Information at SimparicaTrioPI.com.

Revolution Plus

The safe use of Revolution Plus has not been established in kittens less than 8 weeks old or in breeding, pregnant or lactating cats. Reported side effects in clinical trials included lethargy and anorexia. Use with caution in cats with a history of neurologic disorders. Revolution Plus contains sarolaner, a member of the isoxazoline class which has been associated with neurologic adverse reactions, such as tremors, ataxia, and seizures in cats with or without a history of neurologic disorders. In humans, Revolution Plus may be irritating to skin and eyes. See full Prescribing Information at RevolutionPlusPI.com.

*For the treatment and control of Amblyomma americanum, Amblyomma maculatum, Dermacentor variabilis, Haemaphysalis longicornis, Ixodes scapularis, Rhipicephalus sanguineus. †For the treatment and control of roundworm (immature adult and adult Toxocara canis and adult Toxascaris leonina) and hookworm (L4, immature adult, and adult Ancylostoma caninum and adult Uncinaria stenocephala). Prevents flea tapeworm (Dipylidium caninum) by killing fleas.

**Prevents flea tapeworm (Dipylidium caninum) by killing fleas.

References

1. ZMR: Kynetec PetTrak US FTH National Data, January to December 2025.
2. ZMR: Kynetec PetTrack US FTH National Data, January to December 2025.
3. Revolution Plus (selamectin and sarolaner topical solution) [package insert]. Zoetis Inc. Kalamazoo, MI. October 2024.

This product information and marketing content was created by Zoetis, the manufacturer, and is shared on Chewy.com for your convenience. If you have any questions about this product or whether it’s the right choice for your pet, please reach out to your veterinarian for guidance.