Revolution Plus Topical Solution for Cats, 5.6-11 lbs, (Orange Box), 3 Doses (3-mos. supply)

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About This Item

Details

Help protect your four-legged friend from pesky critters with this 6-in-1 broad spectrum monthly Topical Solution for Cats by Revolution Plus. Simply apply the quick-drying, small-volume prescription to help: kill fleas before they lay eggs, kill ticks for a full month, prevent heartworm disease and treat and control roundworms, hookworms and ear mites. This topical medication is suitable for cats and kittens eight weeks of age or older, weighing between 5.6 and 11 pounds.We directly source prescription medications from manufacturers and wholesale distributors registered with the FDA and licensed by applicable state boards. Guaranteed genuine, and where applicable, backed by the manufacturer. One and three count orders of manufacturer-sealed blister packs will arrive in a resealable plastic bag. Please note, due to a manufacturer prompted packaging change, your medication may arrive in new packaging.

Ingredients

Instructions

FAQ

Learn More About Revolution Plus From Our Team of Experts

Veterinarians’ #1 Trusted Choice in Feline Parasite Protection[1]

The Revolution (selamectin) brand has over 25 years of proven protection. Revolution Plus (selamectin and sarolaner topical solution) is the most prescribed medicine for feline parasite defense. It’s available as an easy-to-administer monthly topical solution.

Pest Protection for Indoor & Outdoor Cats

No matter their lifestyle, Revolution Plus protects your cat from the most common parasites:

  • Fleas
  • Tapeworms*
  • 4 Types of Ticks
  • Ear Mites
  • Roundworms
  • Hookworms
  • Heartworm Disease

*Prevents flea tapeworm (Dipylidium caninum) by killing fleas.

Because Every Cat Needs Parasite Protection

It's approved for cats and kittens as young as 8 weeks old, weighing 2.8 lbs or more, and is the only prescription combination preventative that protects against 4 types of ticks.

Protect Your Cat & Earn Rewards From Zoetis

Your 6-or 12-count Revolution Plus purchase may be eligible for Petcare Rewards points. Redeem your points for Rewards toward future vet care and more! Learn More at zoetispetcare.com/rewards

About Zoetis, the Makers of Revolution Plus

At Zoetis, we’ve helped pets live their best lives for over 70 years. Zoetis offers a comprehensive range of products to support your pet’s health—from pest prevention and pain management to allergic itch relief and more. Know that we’ll always be here for you and your pet, no matter what.

Shop Zoetis

IMPORTANT SAFETY INFORMATION

The safe use of Revolution Plus has not been established in kittens less than 8 weeks old or in breeding, pregnant or lactating cats. Reported side effects in clinical trials included lethargy and anorexia. Use with caution in cats with a history of neurologic disorders. Revolution Plus contains sarolaner, a member of the isoxazoline class which has been associated with neurologic adverse reactions, such as tremors, ataxia, and seizures in cats with or without a history of neurologic disorders. In humans, Revolution Plus may be irritating to skin and eyes. See full Prescribing Information at RevolutionPlusPI.com.

References:

  1. ZMR: Kynetec PetTrak Veterinary Channel Review. Q4 2024. Data on file. Zoetis Inc.

RVP-00718

4.8
Rated 4.8 out of 5 stars
5870 Ratings

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

92% Positive

Effectiveness

91% Positive

Ingredients

88% Positive

Long-Term Benefits

90% Positive

1932 Customer Reviews



Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 5 out of 5 stars
By Chris on Mar 30, 2026

Wow

Tried the other which I will not name to no avail. This was amazing, after months of flea problems my cat was better within a day within hours. I started noticing

Tried the other which I will not name to no avail. This was amazing, after months of flea problems my cat was better within a day within hours. I started noticing maybe some fleas falling off him. He had one rough night,the first night like the fleas were attacking him or just leaving him and he was itching a lot since then he’s been what looks like flea free. He’s laying more relaxed now and open, even showing his belly a little occasionally where before it was more contracted and unhappy. so far no side effects are noticed. So far I’d say I’m grateful for this product.


Rated 5 out of 5 stars
By Rachel on Mar 29, 2026

Small amount that dries quickly

It's flea and tick season, again. Purchased this due to the fact that I can no longer buy heartworm chews for the cats. They all hate the liquid and would prefer

It's flea and tick season, again. Purchased this due to the fact that I can no longer buy heartworm chews for the cats. They all hate the liquid and would prefer a pill for flea prevention. However, my vet and the mosquito population here in Ga strongly recommend heartworm prevention as well. It's easy enough to squeeze on the the cats nape and it dries real quick, which I love. Bc I hate the greasy hair some other brands give. I have multiple cats in the house and they groom each other. I'm glad it dries quickly and I don't have to worry about the other cats ingesting the topical.


Rated 5 out of 5 stars
By Erin on Mar 22, 2026

Effective with ticks!!!

I was removing ticks from my 11 lb indoor/outdoor cat just about every other day if not more since it's warmed up a bit outside. Since I gave him this medication,

I was removing ticks from my 11 lb indoor/outdoor cat just about every other day if not more since it's warmed up a bit outside. Since I gave him this medication, I've only found one on him, but it was the day after I applied it so I assume it was still working it's way through his system. It's been at least two weeks now and not a single tick since then!! No bad reaction to the medication and my cat didn't seem to mind it at all.


Rated 5 out of 5 stars
By Lena on Mar 12, 2026

Easy to Fill, Easy to Use

Took my indoor cats to an Airbnb where they picked up fleas. They hadn't been on this before but that told me it was time to start regardless. It was easy to connect

Took my indoor cats to an Airbnb where they picked up fleas. They hadn't been on this before but that told me it was time to start regardless. It was easy to connect this to my vet's office for prescribing and filling and chewy made the process clear and easy and it was filled quickly. Cats didn't try to lick it off or anything (maybe that's just my cats or maybe it's the product, so don't quote me on that). Glad to be able to get this through


Rated 5 out of 5 stars
By Julisa on Feb 5, 2026

Been using for 8+ years on both my cats.

Although a bit pricey, I do love this product. Easy to apply on the back of their necks, I make sure to prevent them from trying to lick it off, and it has proven

Although a bit pricey, I do love this product. Easy to apply on the back of their necks, I make sure to prevent them from trying to lick it off, and it has proven to be effective. I haven’t noticed any side effects ever, and it definitely works - I had stopped using it the first month I moved to FL because my cats were indoor only. Well that was a mistake because they immediately got fleas and I had to throw so many things away. I got them back on the meds and haven’t had any issues so clearly it’s been working!


Rated 5 out of 5 stars
By CONNIE on Feb 17, 2026

You were on top of the prescriptions when our vet wasn't.

Our vet did not confirm our prescriptions in Feb even though we had our annual exam in December. First the confirmation was denied, because he had not had his annual

Our vet did not confirm our prescriptions in Feb even though we had our annual exam in December. First the confirmation was denied, because he had not had his annual checkup. Our file was marked unpaid for the fee to to confirm prescriptions. One month prior, I contacted your staff to set up our renewal which was going to be 2 months later than planned. Your help/service staff helped me set this up in advance so that the confirmation request would come out on the new schedule.


Rated 5 out of 5 stars
By Michelle on Mar 22, 2026

Great protection for Frick!

Living in a little neighborhood where most pets enjoy each leaves me worrying about fleas and Ticks. This med works wonders for Frick. She is always in comfort

Living in a little neighborhood where most pets enjoy each leaves me worrying about fleas and Ticks. This med works wonders for Frick. She is always in comfort and I do not need to worry about her!


Rated 2 out of 5 stars
By Lillian on Feb 5, 2026

Your cat can still get tapeworms on this drug.

Exactly what it says on the tin. Selamectin/sarolaner does NOT prevent tapeworm infection in any capacity. Does it work to prevent fleas, ticks, and some digestive

Exactly what it says on the tin. Selamectin/sarolaner does NOT prevent tapeworm infection in any capacity. Does it work to prevent fleas, ticks, and some digestive parasites? Yes. Quite effectively, too! But, for whatever reason, the manufacturer has chosen not to include tapeworm preventatives in that drug cocktail. My 100% indoor cat now has tapeworms despite consistently being on Revolution Plus. I did some research and it turns out that cats can still get tapeworms, even if they're on this preventative, if they accidentally ingest an infected flea while grooming themselves (remember, these drugs only kill fleas and ticks after they bite, so they can still potentially be on your cat's fur or skin). Sorry, but what is the point of a flea preventative that does not protect against tapeworms, which literally come from infected fleas? Again, considering that these drugs do not prevent fleas from landing on your cat, they should contain an anti-tapeworm drug in the event that your cat ingests a tapeworm-infected flea. I'm now having to treat both of my cats for a ZOONOTIC parasite that this drug cocktail confusingly & frustratingly does not protect them against, despite the fact that a box of it costs as much as an electric bill for a large house. I will be immediately switching to a preventative that DOES contain an anti-tapeworm drug.


Rated 3 out of 5 stars
By John on Feb 18, 2026

Still waiting to see

We adopted Lily from a local shelter. When we got her home, we discovered that she had a lice infestation. Our Vet recommended Revolution Plus. We have doses

We adopted Lily from a local shelter. When we got her home, we discovered that she had a lice infestation. Our Vet recommended Revolution Plus. We have doses her once and will do the second treatment in two days. It will likely take time to see if it will work. She does not go outside, and we have no other cats in the house.


Rated 4 out of 5 stars
By Lyndsay on Feb 3, 2026

Chewy coupons not allowed even though picture item

This product works well to protect my cats. However, Chewy has sent me at least two coupons in the past year with a picture of this product on the coupon, yet

This product works well to protect my cats. However, Chewy has sent me at least two coupons in the past year with a picture of this product on the coupon, yet when I tried to use them to purchase it, it says this product isn't included in the coupon. So that's frustrating and feels like false advertising. I tried multiple times with two different coupon codes. This is so expensive that the coupons make a huge difference.