Revolution Plus Topical Solution for Cats, 11.1-22 lbs, (Green Box), 6 Doses (6-mos. supply)

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About This Item

Details

  • Helps prevent heartworm disease caused by Dirofilaria immitis
  • Kills fleas and helps treat and prevent flea infestations
  • Treats and controls tick infestations
  • Treats and controls ear mites, roundworms, and hookworms
  • Monthly topical parasite protection containing selamectin and sarolaner

Ingredients

Instructions

FAQ

Learn More About Revolution Plus From Our Team of Experts

Veterinarians’ #1 Trusted Choice in Feline Parasite Protection[1]

The Revolution (selamectin) brand has over 25 years of proven protection. Revolution Plus (selamectin and sarolaner topical solution) is the most prescribed medicine for feline parasite defense. It’s available as an easy-to-administer monthly topical solution.

Pest Protection for Indoor & Outdoor Cats

No matter their lifestyle, Revolution Plus protects your cat from the most common parasites:

  • Fleas
  • Tapeworms*
  • 4 Types of Ticks
  • Ear Mites
  • Roundworms
  • Hookworms
  • Heartworm Disease

*Prevents flea tapeworm (Dipylidium caninum) by killing fleas.

Because Every Cat Needs Parasite Protection

It's approved for cats and kittens as young as 8 weeks old, weighing 2.8 lbs or more, and is the only prescription combination preventative that protects against 4 types of ticks.

Protect Your Cat & Earn Rewards From Zoetis

Your 6-or 12-count Revolution Plus purchase may be eligible for Petcare Rewards points. Redeem your points for Rewards toward future vet care and more! Learn More at zoetispetcare.com/rewards

About Zoetis, the Makers of Revolution Plus

At Zoetis, we’ve helped pets live their best lives for over 70 years. Zoetis offers a comprehensive range of products to support your pet’s health—from pest prevention and pain management to allergic itch relief and more. Know that we’ll always be here for you and your pet, no matter what.

Shop Zoetis

IMPORTANT SAFETY INFORMATION

The safe use of Revolution Plus has not been established in kittens less than 8 weeks old or in breeding, pregnant or lactating cats. Reported side effects in clinical trials included lethargy and anorexia. Use with caution in cats with a history of neurologic disorders. Revolution Plus contains sarolaner, a member of the isoxazoline class which has been associated with neurologic adverse reactions, such as tremors, ataxia, and seizures in cats with or without a history of neurologic disorders. In humans, Revolution Plus may be irritating to skin and eyes. See full Prescribing Information at RevolutionPlusPI.com.

References:

  1. ZMR: Kynetec PetTrak Veterinary Channel Review. Q4 2024. Data on file. Zoetis Inc.

RVP-00718

4.8
Rated 4.8 out of 5 stars
6403 Ratings

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

92% Positive

Effectiveness

92% Positive

Ingredients

88% Positive

Long-Term Benefits

92% Positive

2077 Customer Reviews



Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 5 out of 5 stars
By Alaina on Dec 13, 2025
Edgar
Edgar

Easy to apply and incredibly effective!

Finally! Vet pharma came out with an effective all in one product to treat and protect our fur babes! We live on an acreage and I'm fairly certain there's an orange

Finally! Vet pharma came out with an effective all in one product to treat and protect our fur babes! We live on an acreage and I'm fairly certain there's an orange cat distribution center close by, bc we've had a couple strays. With my overwhelming love for animals, I can't let them go without. One particular stray I ended up naming Edgar (Meowin Poe) had a severe case of ear mites and ticks were at an all time high. After months of warming up to this guy and finally earning his trust, my vet prescribed him Revolution Plus and it's been a game changer! It's a very small bottle, but packs a big punch! It's easy to open and the cap has a point to break the seal before applying. Behind one of Edgars ears, he had scratched raw and bloody and over a half dollar in size. In the first month of using it, the smaller scab on the other ear cleared up and hair grew back. The larger one had almost healed to half its size! I was able to take him to get neutered and had his ears flushed. Trying to clean the gunk out, was almost impossible with him. After 2.5 months of use, he is down to a dime size spot, with minimal scratching and all his hair has grown back. He's had no signs of ticks or fleas! I highly recommend this product to anyone who has fur babes that go outside, or in stray cases those who weren't given a choice but still deserve to be cared and looked after.

By Alaina on Dec 13, 2025
Edgar
Edgar

Rated 5 out of 5 stars
By Kris on Jan 22, 2025

My feral outside cat has had no fleas or ticks!

I have a feral cat (so feral anymore!) who lives outside and loves to hunt in our wooded area! He loves for me to hold him. This Spring he jumped up on my lap and

I have a feral cat (so feral anymore!) who lives outside and loves to hunt in our wooded area! He loves for me to hold him. This Spring he jumped up on my lap and I was loving on him until I saw he was loaded with fleas! I had just given him a flea treatment of another brand! I was told he couldn’t have another one until the following month. I got him some CapStar and ordered me Revolution Plus so I’d have it when he couldn’t have it. The CapStar took care of the fleas he had after a week or 2. Then I started dosing him monthly with the Revolution Plus and he hasn’t had a flea or a tick since!!!

By Kris on Jan 22, 2025

Rated 5 out of 5 stars
By Linda on Nov 12, 2025

Revolution Plus WORKS

I've tried quite a few flea/tick prevention topicals. One of them sent my cat to the emergency vet from his reaction. Revolution Plus eliminates any flea or mite

I've tried quite a few flea/tick prevention topicals. One of them sent my cat to the emergency vet from his reaction. Revolution Plus eliminates any flea or mite problem with no ill effects. Cyrus is mostly indoor, but hangs out in my fenced yard so he does need a flea killer (fleas love the Florida climate). Highly recommend this product.

By Linda on Nov 12, 2025

Rated 5 out of 5 stars
By Angelica on Sep 8, 2025

Quick results

Okay so i’ve only used one dosage on my cat and within the first week i saw fast results.. it has been about 3 weeks and i can confidently say it has done wonders,

Okay so i’ve only used one dosage on my cat and within the first week i saw fast results.. it has been about 3 weeks and i can confidently say it has done wonders, i don’t seem him itchy at all really and he is basically bump free. I have such confidence in this medicine long term and I would like to say if you are thinking of making the purchase, do it.

By Angelica on Sep 8, 2025

Rated 5 out of 5 stars
By Carrie on Nov 7, 2025
Jake
Jake

Excellent service on new Rx

Thank you for your good explanation of your pet prescription process, your excellent follow-through with our vet to go over Jake's new prescription, and the excellent

Thank you for your good explanation of your pet prescription process, your excellent follow-through with our vet to go over Jake's new prescription, and the excellent care shown in the handling and delivery of it. Thank you, Chewy!! This household appreciates you a lot! Here's a cute picture of Jake from a previous delivery that I think you may enjoy. :)

By Carrie on Nov 7, 2025
Jake
Jake

Rated 5 out of 5 stars
By Diana on Aug 10, 2025
Binx
Binx

Got rid of the ear mites!

I adopted a 6 month old kitten and he had ear mites and spineless ticks in his ears. He gave the mites to my older cat and I fought those nasty bugs for several

I adopted a 6 month old kitten and he had ear mites and spineless ticks in his ears. He gave the mites to my older cat and I fought those nasty bugs for several months. It took 2 months (2) doses and this product eradicated the mites! I had already gotten rid of the ticks, but I’m sure this would have treated them too!

By Diana on Aug 10, 2025
Binx
Binx

Rated 5 out of 5 stars
By Jeanne on Oct 6, 2024

Ease of application

Even though my big Maine Coon Simon is an indoor only cat, I also have four dogs and a feral cat coming in the back alley-so the feral kitties can bring fleas. My

Even though my big Maine Coon Simon is an indoor only cat, I also have four dogs and a feral cat coming in the back alley-so the feral kitties can bring fleas. My dogs also receive prevention but it just takes one flea hitchhiking inside to start a problem. Revolution Plus has never failed to protect my cat from fleas-other products seem to no longer work in my geographic area of central Texas. The Revolution Plus has never caused any skin irritation or untoward symptoms, so i feel safe in giving it to my beloved pets. Using the spot applicator is really easy. Just plunge the top and pet your kitty-they’ll never know they had their prevention.

By Jeanne on Oct 6, 2024

Rated 5 out of 5 stars
By Cia on Feb 24, 2026

Works well

This is the only one that has ever worked to prevent fleas and ticks. My cats were all ferals and strays from the neighborhood. Unfortunately not one neighbor helped

This is the only one that has ever worked to prevent fleas and ticks. My cats were all ferals and strays from the neighborhood. Unfortunately not one neighbor helped with this cat situation. I started trapping and vetting and the ones that stayed with me were all given this flea med. There are woods in my back yard and it’s inevitable that there they will get a tick. They mostly stay in the back porch but still have an occasional woods adventure. I haven’t had any ticks or fleas on my cats at all. Ever. This is an amazing product.

By Cia on Feb 24, 2026
Anonymous

Rated 5 out of 5 stars
By Mary on May 21, 2025

Prompt service

Jojo is basically an indoor cat but she is allowed on our back deck in a totally fenced yard. I guess she’s happy there because she doesn’t try to escape. But ticks

Jojo is basically an indoor cat but she is allowed on our back deck in a totally fenced yard. I guess she’s happy there because she doesn’t try to escape. But ticks and fleas also like riding in on the other species, mice, voles, chipmunks, squirrels, etc. so she needs flea treatment to prevent her from hosting them.

By Mary on May 21, 2025

Rated 5 out of 5 stars
By JOHN on Feb 22, 2026
Domineaux
Domineaux

Revolution Plus

Easy to apply, and lasts for an entire month. We apply this to our two (2) cats. Revolution Plus goes by the weight of the cat(s). Fortunately, both of our cats

Easy to apply, and lasts for an entire month. We apply this to our two (2) cats. Revolution Plus goes by the weight of the cat(s). Fortunately, both of our cats are in the same weight range. Other popular topical applications do not cover everything that Revolution Plus does, i.e. ear mites. I have confirmed this with other manufacturers of other products. Revolution Plus is well-worth the cost. It is not an expense, because it is keeping our cats healthy.

By JOHN on Feb 22, 2026
Domineaux
Domineaux