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VetriScience GlycoFlex 3 Extra Strength Healthy Hip & Joint Chicken-Flavored Chews with Glucosamine & Green-Lipped Mussel Supplement for Dogs, 120 count

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At a Glance

  • Hip & Joint Support
  • All Lifestages
  • All Breeds
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About This Item

Details

  • Formulated by veterinarians with green-lipped mussel, glucosamine, MSM, DMG, and antioxidants for proactive joint support.
  • Ideal for a variety of dogs, including those that are slowing down or showing signs of weakness in their hind quarters, active dogs, competitive dogs, and dogs recovering from orthopedic surgery.
  • VetriScience Extra Strength Healthy Hip & Joint works to improve your pal’s hind-leg strength and mobility for a happy, healthy life.
  • The bite-sized chews feature a hypoallergenic, hydrolyzed chicken flavor that dogs love.
  • This soft, chewy, and satisfying supplement is made in the USA.

Instructions

FAQ

Key Ingredients

  • Green Lipped Mussel

    Natural source of omega-3 fatty acids and glycosaminoglycans for joint support, common in mobility formulas.

  • Vitamin E

    Fat-soluble vitamin that acts as an antioxidant to protect cells and stabilize fats.

  • Glucosamine

    Joint support nutrient that can help maintain cartilage and improve joint fluid. Common in senior and joint formulas.

  • MSM

    Sulfur compound often paired with glucosamine and chondroitin for joint support.

  • Vitamin C

    Antioxidant used to help preserve nutrients in foods and support immune health.

  • See full ingredient list
VetriScience Healthy Hip & Joint supplements provide advanced joint support for dogs and cats. The veterinarian-formulated, clinically backed formulas are designed to support joint lubrication, cartilage strength, flexibility, comfort, and stronger, more confident movement.
Healthy Hip & Joint supplements are designed to help increase hind-leg strength in pets. They provide mobility support for pets showing signs of poor joint health, including slower walks, stiff movement, or avoiding stairs.
VetriScience offers Healthy Hip & Joint supplements in multiple formats to fit different routines and preferences. Available options include soft chews, easy-split tablets, and granulated powders for convenient daily joint support.
Green-lipped mussel provides targeted joint support by supporting cartilage and helping soothe joint stiffness. This clinically studied ingredient is included as part of VetriScience's advanced joint support approach for dogs and cats.
Glucosamine and MSM help promote healthy connective tissue in the joints. These ingredients support the structural components pets rely on for healthy movement, flexibility, and everyday mobility.
Antioxidants provide additional joint support with free-radical-fighting ingredients. Together with other clinically studied ingredients, they complement a veterinarian-formulated approach to maintaining healthy joints and comfortable movement.
VetriScience Healthy Hip & Joint provides condition-specific support backed by science for both dogs and cats. With multiple supplement formats and clinically studied ingredients, the line is designed to make ongoing joint and mobility support easier to incorporate into a pet's routine.

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Questions & Answers

42 Customer Questions

I started these a few days ago for my 165 pound Newfoundland dog and his breath is smelling really fishy now. He is getting 5 Chews a day per instructions on the bag. Is this normal to get bad breath from these?

is there a medical difference between GlycoFlex plus an GlycoFlex 3?

Answer by Chewy • Apr 06, 2018
Both formulas have the same levels of Glucosamine and MSM. The VetriScience GlycoFlex Plus Joint Support Bite-Sized Dog Chews have added Chondroitin for pets who may benefit more from it.

What is the difference between this and the “plus’?

Answer by Chewy • Oct 15, 2020
Both products are proven a 41% increase in hind leg strength in just 4 weeks, but the VetriScience GlycoFlex Stage III is geared more towards seniors. VetriScience GlycoFlex Stage III is also recommended for dogs with a maximum need for joint and connective tissue support, joint and connective tissue support, geriatric and working dogs as well as to support normal recovery after orthopedic surgery.

is there a shelf life for opened and.or unopened packages of Glycoflex III

Answer by Chewy • Jan 09, 2019
The expiration date is located next to the lot number on all of VetriScience's products. On the bags, it will be on the back and looks like it came from a dot matrix printer. The lot number is 8 digits long, then a space, then 4 more digits indicating month and year.
Reviews
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4.6
Rated 4.6 out of 5 stars
2242 Ratings
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Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Active Ingredients

89% Positive

Dosage and Administration

91% Positive

Effectiveness

91% Positive

Quality and Purity

87% Positive

1303 Customer Reviews

Rated 5 out of 5 stars
Verified Purchase
By Karen on Dec 25, 2025

Very helpful

We’ve noticed a huge difference in our lab since he started taking these. I’m not a big believer in supplements, but these worked for us. Our lab is almost 13, degenerative

We’ve noticed a huge difference in our lab since he started taking these. I’m not a big believer in supplements, but these worked for us. Our lab is almost 13, degenerative disc disease, arthritis,and old. Since taking these he has had more better days than bad days.

Rated 5 out of 5 stars
Verified Purchase
By SusieJodyFrankie on Nov 5, 2019

8.5 yr old Rottweiler with joint dysplagia

Our rottie was diagnosed with joint dysplagia at 2 years. We always wondered when her limbs would no longer support her as she grew over 100lbs. Because of that,

Our rottie was diagnosed with joint dysplagia at 2 years. We always wondered when her limbs would no longer support her as she grew over 100lbs. Because of that, she has been on EVERY supplement for joints that I could get my hands on. I've tried everything on the market to give her more pain-free days. She went over a year without being able to go on walks. Her favorite thing in the world is swimming, so I felt that I owed it to her to just keep trying. About 3 months ago, I bought Glycoflex...moreso for my younger, frisbee catching bulldog. Surprisingly, we have our Rottweiler back! My husband and I cannot believe how transformed Susie is. Her back end no longer shakes when she stands still. She can walk a mile and not lag behind. And she seems REALLY happy! She even jumped up on the bed and is seeking out being petted. It has been years since we have seen her like this. So grateful for this product. She will be on it the rest of her life! XOXO

Rated 5 out of 5 stars
Verified Purchase
By Patricia on Sep 1, 2016

Great product, excellent price

My 12+ year old mutt, Darcy, has been on this product for about 6 years now. She had no specific problems, but I had some on hand for her sister, and when she passed,

My 12+ year old mutt, Darcy, has been on this product for about 6 years now. She had no specific problems, but I had some on hand for her sister, and when she passed, thought I would continue giving them to Darcy. She eats the treats without any complaints and is able to run, jump and pretty much do anything she wants. The vet said she has some mild arthritis in her back, so I think these help to keep problems at a minimum. She is a trim 36 pounds, that helps too! Her new sister, a chunkier 44 lb mix of beagle, corgi and lab, has also been taking this for about 2 years now. The vet said a couple years ago Emmie has hip dysplasia, but Em doesn't seem to know that. She likes to go running with me, loves to run at the park and does the little dancing doggy thing for her treats (her idea, not mine). My only complaint with this product is there is a very pronounced and yucky smell lately. It never smelled bad before. But the dogs don't mind, maybe it enhances the flavor for them.

Rated 5 out of 5 stars
Verified Purchase
By RoniJ on Oct 26, 2016
Top 100 Contributor

New energy for my elder schnauzer

My elder miniature schnauzer Cicero will be 15 in December and I'm sure he's developed some arthritis. What dog of that age wouldn't? He tries hard to keep up with

My elder miniature schnauzer Cicero will be 15 in December and I'm sure he's developed some arthritis. What dog of that age wouldn't? He tries hard to keep up with his baby brother, 1-1/2 year old Apollo. For the past year we've been giving him Dasuquin, which had a noticeable effect immediately as he began to hop a few running steps trying to catch up to a thrown toy in our yard. As our supply was running low, I decided to try the Glycoflex Stage III - just one chew per day based on his weight of about 17 lbs. The chews are soft, shaped like a small dog bone, and too much for him to handle all in one piece, even though all his teeth are intact. But they're very easy to break cleanly into four smaller bite-sizes for him. We now see noticeably more energy in his ability to run. He still hops like a bunny, but faster and longer, so I think there's really something good going on here. Hoping for long-term results. Also, with 120 chews providing more joint support than the package of 84 Dasuquin, it's also a much better value.

Rated 4 out of 5 stars
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By Mary on Feb 26, 2025

I Think They Help

We started using these with our older, arthritic dog several years ago. She's gone now, but I think they may have helped take the edge off a bit of her pain. It's

We started using these with our older, arthritic dog several years ago. She's gone now, but I think they may have helped take the edge off a bit of her pain. It's so hard to tell if a suppliment like this is working because the change is so gradual. Asisde from the price point for my large dogs, I still believe they provide some value, if only to make me feel like I'm helping to provide some relief from the pain. In that way, I guess they help me as much as my dog. Vet recommended.

Rated 5 out of 5 stars
Verified Purchase
By Sarah on Feb 11, 2025

These really made a difference!

My dog Roxy is an 8 year old cattle dog mix who LOVES to jump and run and play with soccer balls. We have played with soccer balls multiple times a day for most

My dog Roxy is an 8 year old cattle dog mix who LOVES to jump and run and play with soccer balls. We have played with soccer balls multiple times a day for most of her life, but over the last year or so the vet told me she had developed arthritis in a couple of joints and she would sometimes limp a little after a long play session with the ball. I tried giving her fish oil and a joint supplement from an orange container (dont want to name shame) for months but it didn't really help and her limping was getting worse, it was almost daily now. I did some research and came across this brand "Glycoflex 3 extra strength" and decided to give it a try. Within just a couple of weeks of being on it, she didn't limp after a play session anymore! She is usually a very picky eater but she will eat these with no issues and thinks they are a treat. I feel so much better playing with her knowing that she won't be in pain afterwards! These are well worth the money and have made such a positive impact on my dog's life.

Rated 4 out of 5 stars
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By Smatheus on Mar 22, 2018

My Dog Loves Them

I got these for our 75lb Old English Sheepdog/Boxer mix. He's 10 years old and is starting to get a bit arthritic but he still loves to go on walks and runs with

I got these for our 75lb Old English Sheepdog/Boxer mix. He's 10 years old and is starting to get a bit arthritic but he still loves to go on walks and runs with us. He's been running his whole life and I knew that running would start to become more difficult for him. We wanted to start him on these to help him maintain his current strength and mobility. He's been on this supplement for about 4 months. So far we haven't noticed any changes in his mobility but he's still very active and strong for a senior dog. He has become a bit more playful with our younger dogs since being on this supplement. So I do think this is helping him maintain his energy, mobility and strength. The chews are very smelly which is why I gave 4 stars. Personally I hate the smell. Seriously can't stand the smell when I open the bag but our boy loves these chews! The directions for use are simple to follow and they do recommend that you give more chews per day for 4-6 weeks when you initially start giving these, which can get kind of pricey when you have a large dog and need to give 4 or more a day. Now that he's over the initial period our boy gets two chews a day. We just toss a chew in his bowl at mealtime and he scarfs it down.

Rated 5 out of 5 stars
Verified Purchase
By mycatlovesthis on May 2, 2017

My Dog loves these and she's definitely feeling better.

My 8-yr old border collie mix has hip problems that have started slowing her down. I give her Adaquan every month but my Vet suggested I add in a daily supplement

My 8-yr old border collie mix has hip problems that have started slowing her down. I give her Adaquan every month but my Vet suggested I add in a daily supplement and recommended these. GlycoFlex Stage III Ultimate Strength Joint Support are just the ticket! She loves them, thinks they are a treat so we do some training, she gets her "treat" and feels better. What could be easier than that? I highly recommend for picky eaters like my dog. These are soft and she really loves the taste, unlike some others we've tried in the past.

Rated 5 out of 5 stars
Verified Purchase
By Caitlin on Jun 25, 2020

Immediate difference!

Darius has what our vet thinks is a slipped disc, and it's significantly slowed him down over the years. He wasn't enjoying our walks, his hind end would skid out

Darius has what our vet thinks is a slipped disc, and it's significantly slowed him down over the years. He wasn't enjoying our walks, his hind end would skid out sometimes... He was just getting to be an old dude. We had him on Rx meds but they're terrible for his liver and kidneys. So we thought we'd try these. I have had great luck with VetriScience in the past, so I went for it. First, he LOVES these. Next, his interest in walks improved almost immediately. He can walk for longer and seems happier about it too. The chews are big, like the size of small milkbones, but he's 50# so they're perfect for him.

Rated 5 out of 5 stars
Verified Purchase
By Phyllis on Oct 15, 2024

Quality of life

I’ve been giving this joint product to my old rescue dogs when I adopted them at 9 and 10 years of age. They are larger dogs, 55 and 90 lbs, and they are both 15+

I’ve been giving this joint product to my old rescue dogs when I adopted them at 9 and 10 years of age. They are larger dogs, 55 and 90 lbs, and they are both 15+ years old! They definitely have arthritis and cannot jump into the car but still can go for short walks and navigate stairs. They definitely have quality of life in their very senior years!