Simparica Chewable Tablet for Dogs, 88.1-132 lbs, (Brown Box), 3 Chewable Tablets (3-mos. supply)

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About This Item

Details

  • 35-Day Flea and Tick Prevention for Dogs: Simparica is a tasty, once-a-month chewable that protects your dog from fleas and ticks for 35 days, even if the next dose is a few days late.
  • Kills 6 Types of Ticks: Proven to kill Gulf Coast, Brown Dog, Deer, American Dog, Lone Star, and Asian Longhorned ticks.
  • Helps Prevent Lyme Infections: FDA-approved to block infections that may cause Lyme disease by killing deer ticks.
  • Fast-Acting Relief: Starts killing fleas within 3 hours and ticks within 8 hours. Kills adult fleas before they lay eggs to help stop infestations fast.
  • Tasty, Once-a-Month Chewable: Pork-liver flavored for easy dosing. Approved for dogs 6 months and older weighing at least 2.8 lbs, and backed by a 100% satisfaction guarantee on prevention.

Ingredients

Instructions

FAQ

Learn More About Simparica From Our Team of Experts

Protects Dogs From Ticks & Fleas for 35 days

Simparica is tasty pork liver-flavored, veterinarian-recommended monthly chew that protects your dog from fleas and ticks for a full 35 days.[1] It works fast and starts to kill fleas in 3 hours and ticks in 8 hours.[2] Simparica is approved for dogs 6+ months of age, weighing 2.8 lbs or more.

FDA-Approved to Prevent Lyme Infections*

Because it kills deer ticks, Simparica is FDA-approved to block infections that may cause Lyme disease. It kills 6 different types of ticks, including:

  • Gulf Coast Tick
  • Deer Tick
  • American Dog Tick
  • Lone Star Tick
  • Brown Dog Tick
  • Asian Longhorned Tick

Satisfaction Guaranteed

Simparica comes with a 100% satisfaction guarantee on prevention—so you can feel confident choosing fast, reliable protection. It’s a simple way to stay proactive about your dog’s care, with support you can count on.

Protect Your Dog & Earn Rewards From Zoetis

Your 6-or 12-count Simparica purchase may be eligible for Petcare Rewards points. Redeem your points for Rewards toward future vet care and more! Learn More at zoetispetcare.com/rewards

About Zoetis, the Makers of Rimadyl

At Zoetis, we’ve helped pets live their best lives for over 70 years. Zoetis offers a comprehensive range of products to support your pet’s health—from pest prevention and pain management to allergic itch relief and more. Know that we’ll always be here for you and your pet, no matter what.

Shop Zoetis

IMPORTANT SAFETY INFORMATION

Simparica is for use only in dogs 6 months of age and older. Simparica, which contains sarolaner, a member of the isoxazoline class, may cause neurologic signs such as tremors, unsteadiness, and/or seizures in dogs with or without a history of neurologic disorders. Simparica has not been evaluated in pregnant, breeding, or lactating dogs. The most common adverse reactions in clinical trials were vomiting and diarrhea. See full Prescribing Information at SimparicaPI.com.

*Data on file, Zoetis Services LLC.

References:Six RH, Liebenberg J, Honsberger NA, Mahabir SP. Comparative speed of kill of sarolaner (Simparica®) and afoxolaner (NexGard®) against induced infestations of Ctenocephalides felis on dogs. Parasit Vectors. 2016;9:90Honsberger NA, Six RH, Heinz TJ, et al. Efficacy of sarolaner in the prevention of Borrelia burgdorferi and Anaplasma phagocytophilum transmission from infected Ixodes scapularis to dogs. Vet Parasitol. 2016;222:67–72 (AR-04287).

SMP-00748

4.7
Rated 4.7 out of 5 stars
598 Ratings

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

90% Positive

Effectiveness

92% Positive

Ingredients

83% Positive

Long-Term Benefits

89% Positive

205 Customer Reviews



Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 2 out of 5 stars
By Robert on Mar 25, 2026

Messed up order

You doubled 1 dogs order and then sent the other dogs order as 6 months. Why? Emailed without answers. Removed more from my account than l appoved.

You doubled 1 dogs order and then sent the other dogs order as 6 months. Why? Emailed without answers. Removed more from my account than l appoved.


Rated 1 out of 5 stars
By April on Dec 10, 2025

Beware!!!

I strongly believe this is what led us to have to ultimately put our dog down. Do not give this poison! The next morning after his pill he was trembling and weak

I strongly believe this is what led us to have to ultimately put our dog down. Do not give this poison! The next morning after his pill he was trembling and weak. He collapsed and never could get back up. Eventually his neurological system shut down. He was fine before. The pill was the only thing different that was ingested. This medicine causes seizures & neurological issues. After a couple days he still was not able to get up, eat, or potty & breathing was getting worse. Eventually he had to be put down. We miss him so much!!


Rated 5 out of 5 stars
By Barbara on Feb 5, 2026

Works well for the intended purpose.

Love the fact that it kills the fleas and ticks on the dogs and I don't have to worry about them being infested with the fleas and ticks. They drop off pretty soon

Love the fact that it kills the fleas and ticks on the dogs and I don't have to worry about them being infested with the fleas and ticks. They drop off pretty soon after they get on the dogs.


Rated 1 out of 5 stars
By Juli on Jan 3, 2026

skin reaction

My dog is a purebred with skin sensitivity issues. If you have one similar, beware. This medication has caused plaque-like lesions that are very itchy causing my

My dog is a purebred with skin sensitivity issues. If you have one similar, beware. This medication has caused plaque-like lesions that are very itchy causing my dog to suffer. This has lasted a month. This isn't for him, too bad because I liked the idea of one pill per month.


Rated 5 out of 5 stars
By Susan on Mar 9, 2026

good service

the availability of medicine as not carried by my vet anymore and the brand they do carry my babies do not like

the availability of medicine as not carried by my vet anymore and the brand they do carry my babies do not like


Rated 5 out of 5 stars
By Greg on Jan 10, 2026

this stuff is amazing

Don't waste your money on Over the counter feel meds, we tried for years, fleas never die, with this, they were GONE in a Day or less, no where in the house, yard

Don't waste your money on Over the counter feel meds, we tried for years, fleas never die, with this, they were GONE in a Day or less, no where in the house, yard or on the pet. Almost instantly... SO GOOD


Rated 2 out of 5 stars
By David on Mar 21, 2026

Unboxed

The bag of dog food was delivered unboxed!.. if it was raining it would have been ruined

The bag of dog food was delivered unboxed!.. if it was raining it would have been ruined


Rated 5 out of 5 stars
By Courtney on Jan 1, 2026

Easy and work

I was hesitant the first time I got this for my 108 lb pup but it works. It does exactly what it says an it was easy to get my dog to eat it. Highly recommend i

I was hesitant the first time I got this for my 108 lb pup but it works. It does exactly what it says an it was easy to get my dog to eat it. Highly recommend it.


Rated 1 out of 5 stars
By Joellen on Jan 23, 2026

For dogs, not humans.

I can’t rate this because Bear won’t tell me what he thinks about taste, texture or effectiveness

I can’t rate this because Bear won’t tell me what he thinks about taste, texture or effectiveness


Rated 5 out of 5 stars
By Betty on Nov 23, 2025

Only brand flew and ticks meds we use for our dogs

I would recommend this brand of flee and tick meds to everyone who has dogs. My dogs never have any problems and I know they are protected so it makes me feel g

I would recommend this brand of flee and tick meds to everyone who has dogs. My dogs never have any problems and I know they are protected so it makes me feel good.