Simparica Chewable Tablet for Dogs, 5.6-11 lbs, (Purple Box), 3 Chewable Tablets (3-mos. supply)

Have a Chewy account?
Sign in to quickly add pet health details.
$35.27 First Time Autoship Price
this order
Save 50% (up to $50) today when you set up Autoship. 

$67.01 Autoship Price
(-5%) future orders
  • Keep saving 5% on every order
  • Never miss a dose with easy refills
  • Skip, change, or cancel anytime
$70.54 Chewy Price
($23.52 /ea)
Promo, Save 20% on first Rx order with code RX20

In Stock
FREE delivery
Usually arrives in 3-5 days
Prescription approval made easy
We’ll reach out to your vet clinic.

No interest if paid in full in 6 months on PayPal purchases of $149+. .

Medications ship separately. Delivery times may vary.

About This Item

Details

  • 35-Day Flea and Tick Prevention for Dogs: Simparica is a tasty, once-a-month chewable that protects your dog from fleas and ticks for 35 days, even if the next dose is a few days late.
  • Kills 6 Types of Ticks: Proven to kill Gulf Coast, Brown Dog, Deer, American Dog, Lone Star, and Asian Longhorned ticks.
  • Helps Prevent Lyme Infections: FDA-approved to block infections that may cause Lyme disease by killing deer ticks.
  • Fast-Acting Relief: Starts killing fleas within 3 hours and ticks within 8 hours. Kills adult fleas before they lay eggs to help stop infestations fast.
  • Tasty, Once-a-Month Chewable: Pork-liver flavored for easy dosing. Approved for dogs 6 months and older weighing at least 2.8 lbs, and backed by a 100% satisfaction guarantee on prevention.

Ingredients

Instructions

FAQ

Learn More About Simparica From Our Team of Experts

Protects Dogs From Ticks & Fleas for 35 days

Simparica is tasty pork liver-flavored, veterinarian-recommended monthly chew that protects your dog from fleas and ticks for a full 35 days.[1] It works fast and starts to kill fleas in 3 hours and ticks in 8 hours.[2] Simparica is approved for dogs 6+ months of age, weighing 2.8 lbs or more.

FDA-Approved to Prevent Lyme Infections*

Because it kills deer ticks, Simparica is FDA-approved to block infections that may cause Lyme disease. It kills 6 different types of ticks, including:

  • Gulf Coast Tick
  • Deer Tick
  • American Dog Tick
  • Lone Star Tick
  • Brown Dog Tick
  • Asian Longhorned Tick

Satisfaction Guaranteed

Simparica comes with a 100% satisfaction guarantee on prevention—so you can feel confident choosing fast, reliable protection. It’s a simple way to stay proactive about your dog’s care, with support you can count on.

Protect Your Dog & Earn Rewards From Zoetis

Your 6-or 12-count Simparica purchase may be eligible for Petcare Rewards points. Redeem your points for Rewards toward future vet care and more! Learn More at zoetispetcare.com/rewards

About Zoetis, the Makers of Rimadyl

At Zoetis, we’ve helped pets live their best lives for over 70 years. Zoetis offers a comprehensive range of products to support your pet’s health—from pest prevention and pain management to allergic itch relief and more. Know that we’ll always be here for you and your pet, no matter what.

Shop Zoetis

IMPORTANT SAFETY INFORMATION

Simparica is for use only in dogs 6 months of age and older. Simparica, which contains sarolaner, a member of the isoxazoline class, may cause neurologic signs such as tremors, unsteadiness, and/or seizures in dogs with or without a history of neurologic disorders. Simparica has not been evaluated in pregnant, breeding, or lactating dogs. The most common adverse reactions in clinical trials were vomiting and diarrhea. See full Prescribing Information at SimparicaPI.com.

*Data on file, Zoetis Services LLC.

References:Six RH, Liebenberg J, Honsberger NA, Mahabir SP. Comparative speed of kill of sarolaner (Simparica®) and afoxolaner (NexGard®) against induced infestations of Ctenocephalides felis on dogs. Parasit Vectors. 2016;9:90Honsberger NA, Six RH, Heinz TJ, et al. Efficacy of sarolaner in the prevention of Borrelia burgdorferi and Anaplasma phagocytophilum transmission from infected Ixodes scapularis to dogs. Vet Parasitol. 2016;222:67–72 (AR-04287).

SMP-00748

4.8
Rated 4.8 out of 5 stars
846 Ratings

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

90% Positive

Effectiveness

87% Positive

Ingredients

88% Positive

Long-Term Benefits

91% Positive

268 Customer Reviews



Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 5 out of 5 stars
By Suzanne on Apr 1, 2026

Works Quickly

This is so convenient and easy. I have two furbabies, and I have tried the drops on the neck and flea/tick collars. I don’t like either, and neither do my babies

This is so convenient and easy. I have two furbabies, and I have tried the drops on the neck and flea/tick collars. I don’t like either, and neither do my babies. The chews are one and done. They think they got a treat. So happy I changed. Also, I’m finding the fleas dead this time, on the floor.


Rated 5 out of 5 stars
By Becky on Feb 11, 2026

It works

I've used topicals for years but they stopped working. I've only used the Simparica for 2 months so hopefully it will continue to work well as warmer weather comes

I've used topicals for years but they stopped working. I've only used the Simparica for 2 months so hopefully it will continue to work well as warmer weather comes along. I plan to switch to Simparica Trio when it's time for Chloe's heartworm preventative.


Rated 5 out of 5 stars
By Vincent on Feb 11, 2026

So far so goid!

I watched for side effects- and after 10 days of first the first application- the only thing we noticed was a fussier appetite. Other than that our Shihtzu puppy

I watched for side effects- and after 10 days of first the first application- the only thing we noticed was a fussier appetite. Other than that our Shihtzu puppy was her regular lovable self!


Rated 5 out of 5 stars
By Anne on Mar 25, 2026

Worked great against fleas.

When my dog's previous flea prevention suddenly stopped working, I tried this one and it worked great.

When my dog's previous flea prevention suddenly stopped working, I tried this one and it worked great.


Rated 5 out of 5 stars
By Linda on Mar 13, 2026

Impressed with Chewy

I have found the on line ordering with Chewy to be user friendly and shipments are received in a timely manner.

I have found the on line ordering with Chewy to be user friendly and shipments are received in a timely manner.


Rated 1 out of 5 stars
By Mommy on Nov 5, 2025

Failure to receive this item

I Was Overcharged for my order & I Will Definitely Be Calling Chewy, I am Not Happy with Being Over-Charged plus not receiving Chloe’s Medicine. Also I can’t count

I Was Overcharged for my order & I Will Definitely Be Calling Chewy, I am Not Happy with Being Over-Charged plus not receiving Chloe’s Medicine. Also I can’t count the number of times I’ve called desperately trying to explain to customer service that I have always been on auto-shipments n auto pay but receiving messages saying my auto shipments needs to be activated so I was charged more plus I use to get coupons to use towards order’sPlease train customer service to look at account’s properly & thoroughly especially those of us who are using your auto-payments & shipments every 3 months, unfortunately they do not comprehend & are constantly putting different dates when my fur babies r due their Simparica. I been a faithful customer of yours please help me straighten this issue out, I would really appreciate it n I would really like to stay as one of your customers (ps the CSR’S I have spoke to were respectful n courteous and I thank-you


Rated 5 out of 5 stars
By CAROL on Jan 3, 2026

The ease of administrating this product to Sandy

Sandy just gobbled right up it is great to be able to give your dog proper medication with no problems and actually have them enjoy it as a treat

Sandy just gobbled right up it is great to be able to give your dog proper medication with no problems and actually have them enjoy it as a treat


Rated 5 out of 5 stars
By Charlene on Jan 20, 2026

Pricing

I was so thankful you had the medication. For 6 months supply is great I sign up automatically for every 6 moths

I was so thankful you had the medication. For 6 months supply is great I sign up automatically for every 6 moths


Rated 1 out of 5 stars
By Jacinta on Jan 31, 2026

Wrong item sent

I called to get an Rx for cerenia shipped but they sent simparica which I have more than enough of

I called to get an Rx for cerenia shipped but they sent simparica which I have more than enough of


Rated 5 out of 5 stars
By Guadalupe on Jan 24, 2026

Fleas are gone

Amazing how this medication completely removed,. all the fleas that we were dealing with.

Amazing how this medication completely removed,. all the fleas that we were dealing with.