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Simparica Chewable Tablet for Dogs, 11.1-22 lbs, (Orange Box), 3 Chewable Tablets (3-mos. supply)

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$35.85 First Time Autoship Price
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$68.12 Autoship Price
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About This Item

Details

  • 35-Day Flea and Tick Prevention for Dogs: Simparica is a tasty, once-a-month chewable that protects your dog from fleas and ticks for 35 days, even if the next dose is a few days late.
  • Kills 6 Types of Ticks: Proven to kill Gulf Coast, Brown Dog, Deer, American Dog, Lone Star, and Asian Longhorned ticks.
  • Helps Prevent Lyme Infections: FDA-approved to block infections that may cause Lyme disease by killing deer ticks.
  • Fast-Acting Relief: Starts killing fleas within 3 hours and ticks within 8 hours. Kills adult fleas before they lay eggs to help stop infestations fast.
  • Tasty, Once-a-Month Chewable: Pork-liver flavored for easy dosing. Approved for dogs 6 months and older weighing at least 2.8 lbs, and backed by a 100% satisfaction guarantee on prevention.

Ingredients

Instructions

FAQ

Learn More About Simparica From Our Team of Experts

Protects Dogs From Ticks & Fleas for 35 days

Simparica is tasty pork liver-flavored, veterinarian-recommended monthly chew that protects your dog from fleas and ticks for a full 35 days.[1] It works fast and starts to kill fleas in 3 hours and ticks in 8 hours.[2] Simparica is approved for dogs 6+ months of age, weighing 2.8 lbs or more.

FDA-Approved to Prevent Lyme Infections*

Because it kills deer ticks, Simparica is FDA-approved to block infections that may cause Lyme disease. It kills 6 different types of ticks, including:

  • Gulf Coast Tick
  • Deer Tick
  • American Dog Tick
  • Lone Star Tick
  • Brown Dog Tick
  • Asian Longhorned Tick

Satisfaction Guaranteed

Simparica comes with a 100% satisfaction guarantee on prevention—so you can feel confident choosing fast, reliable protection. It’s a simple way to stay proactive about your dog’s care, with support you can count on.

Protect Your Dog & Earn Rewards From Zoetis

Your 6-or 12-count Simparica purchase may be eligible for Petcare Rewards points. Redeem your points for Rewards toward future vet care and more! Learn More at zoetispetcare.com/rewards

About Zoetis, the Makers of Rimadyl

At Zoetis, we’ve helped pets live their best lives for over 70 years. Zoetis offers a comprehensive range of products to support your pet’s health—from pest prevention and pain management to allergic itch relief and more. Know that we’ll always be here for you and your pet, no matter what.

Shop Zoetis

IMPORTANT SAFETY INFORMATION

Simparica is for use only in dogs 6 months of age and older. Simparica, which contains sarolaner, a member of the isoxazoline class, may cause neurologic signs such as tremors, unsteadiness, and/or seizures in dogs with or without a history of neurologic disorders. Simparica has not been evaluated in pregnant, breeding, or lactating dogs. The most common adverse reactions in clinical trials were vomiting and diarrhea. See full Prescribing Information at SimparicaPI.com.

*Data on file, Zoetis Services LLC.

References:Six RH, Liebenberg J, Honsberger NA, Mahabir SP. Comparative speed of kill of sarolaner (Simparica®) and afoxolaner (NexGard®) against induced infestations of Ctenocephalides felis on dogs. Parasit Vectors. 2016;9:90Honsberger NA, Six RH, Heinz TJ, et al. Efficacy of sarolaner in the prevention of Borrelia burgdorferi and Anaplasma phagocytophilum transmission from infected Ixodes scapularis to dogs. Vet Parasitol. 2016;222:67–72 (AR-04287).

SMP-00748

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4.8
Rated 4.8 out of 5 stars
2297 Ratings
Terms & Conditions

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

92% Positive

Effectiveness

90% Positive

Ingredients

89% Positive

Long-Term Benefits

90% Positive

769 Customer Reviews

Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 5 out of 5 stars
By Tammy on Jun 10, 2025

Saving me gas money and so easy

When a neighbor told me that I could get my Cudi his flea meds cheaper through chewy.com, I knew I had to check it out. I normally just buy a three month supply

When a neighbor told me that I could get my Cudi his flea meds cheaper through chewy.com, I knew I had to check it out. I normally just buy a three month supply at a time. I normally pay almost $80 for a three month supply at the vet. I'm saving $20 on his medication along with not having to drive a half hour to get it. It's so easy, just select the medicine, put in your vet information and chewy does the rest. Don't know why I haven't done this sooner. Thank you, chewy!

Rated 5 out of 5 stars
By Joe on Jul 14, 2025

As always, you guys were great

I came, I ordered, you delivered. All good! Attached is a picture of Too-Tall, looking at the birthday card you sent him. He'll be 10 October 15th.

I came, I ordered, you delivered. All good! Attached is a picture of Too-Tall, looking at the birthday card you sent him. He'll be 10 October 15th.

Rated 5 out of 5 stars
By Annex on Jul 28, 2019

Great product

I used to do Frontline and it’s a good product but not strong enough if your living in a place that is more wooded area. So I move to a more country backyard was

I used to do Frontline and it’s a good product but not strong enough if your living in a place that is more wooded area. So I move to a more country backyard was already infested of fleas. I ran to my vet because both dogs had fleas. Thank god for Chewy and Simpirica I bought only 2 tablets in my vet and found it expensive with Cap Star .. I got to the Internet and purchase from chewy they were fast in getting my Veterinary information and amén I received a full box .This really works!!!! My babies are protected.

Rated 5 out of 5 stars
By Nikki on Aug 20, 2024

AMAZING SERVICE

First off the product is incredible I’ve been using it successfully for years on my very sensitive belly and skin dog, but what more impressive than the product

First off the product is incredible I’ve been using it successfully for years on my very sensitive belly and skin dog, but what more impressive than the product is Chewy’s service! I messed up and somehow canceled my autoship, when I went to give my dogs their flea product this month I realized I was out. My one dog had a vet appointment so I figured no biggy I will get a single dose from my vet to get me by…. Well little do I know they were out of stock and I was leaving for vacation in just 3 days. So I placed an order with chewy and explained my situation. Offered to pay for overnight shipping and they said “no need to pay we have you” NO JOKE, I spoke to chewy 4pm by 12 noon the next day my flea product was on my doorstep. What an incredible company. Not only that the associate I spoke with was absolutely incredible, kind, compassionate and understanding. I am beyond grateful to be their customer!

Rated 5 out of 5 stars
By Karen on May 24, 2020

Excellent but Crazy Expensive!

I am in South Florida and NONE of the over the counter flea medications worked! I finally gave up, went to the vet and they gave me Simparica, it is unbelievable

I am in South Florida and NONE of the over the counter flea medications worked! I finally gave up, went to the vet and they gave me Simparica, it is unbelievable that for the first time in 8 years my dog is completely flealess for over a month BUT I may need a second job thanks to such disgustingly greedy flea medication companies.

Rated 4 out of 5 stars
By Jan-Marie on Oct 19, 2024

Little Dogs' Relief

Little Dog has no fleas or ticks. He did develop a constant itch (not sure if that's a side effect) He's protected from those pesky critters and that was important

Little Dog has no fleas or ticks. He did develop a constant itch (not sure if that's a side effect) He's protected from those pesky critters and that was important to me. Fleas, ticks & heart worms are useless and an unnecessary evil

Rated 3 out of 5 stars
By Jo on Aug 24, 2024

Not 50% off as advertised with hard to discover cap.

I started autoship with this order to get 50% off as advertised. Order total was $230. 50% off would have been $115. I was given $90 off because I am told there

I started autoship with this order to get 50% off as advertised. Order total was $230. 50% off would have been $115. I was given $90 off because I am told there is a cap on promotion. I went back to find the disclaimer on the 5% off eligible for today. Clicked on more info and couldn't find any cap. I have received other offers from chewy. I prepare my cart to get the offer but then am told I don't qualify for the offer. I shouldn't have to read every small print to get chewys offers. It is a waste of my time. I now disregard most of the offers chewys offers. I don't have time to svour their site for disclaimers. I purchase about $150 a month or more from chewy and I have had an account there for years. They have good availability and are a good company but beware of offers!

Rated 1 out of 5 stars
By Audrey on Apr 13, 2025

Caused my dog to have seizures

I gave my dog a dose in the morning. By the afternoon she started having seizures, a few that were grand mal seizures, and for a few hours she was having about one

I gave my dog a dose in the morning. By the afternoon she started having seizures, a few that were grand mal seizures, and for a few hours she was having about one seizure a minute. The vet wanted to run multiple tests and was talking about having to euthanize, believing it had nothing to do with the medication. However, we decided to wait it out and see what happened over the next few days. The seizures gradually decreased in frequency and intensity and four days later she was seizure free and hasn't had a seizure since. We will not be trying this medication again.

Rated 5 out of 5 stars
By Kesia on Jun 30, 2025

Keeping my dog safe

So grateful for these easy chewable tablets to keep my girl safe all year long. She eats these like they are a treat (no need to hide them in a pill pocket or peanut

So grateful for these easy chewable tablets to keep my girl safe all year long. She eats these like they are a treat (no need to hide them in a pill pocket or peanut butter). Definitely puts my mind at ease on all of our adventures knowing she's protected from fleas, ticks, and heartworm disease.

Rated 5 out of 5 stars
By Marina on Apr 18, 2026

Good tick med

Been using with all my babies.. Jake doing great on it.

Been using with all my babies.. Jake doing great on it.