Proin (phenylpropanolamine hydrochloride) Chewable Tablets for Dogs, 25-mg, 30 tablets
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About This Item
Details
- Effectively treats urinary incontinence in dogs by strengthening the urethral sphincter muscle
- Formulated with trusted Phenylpropanolamine Hydrochloride in a chewable, liver-flavored tablet
- Easy administration and appealing to dogs. Typically shows results within a few weeks, helping prevent accidents and restoring quality of life for both owners and pets
- Proin chewable tablets release the medication into the dog's system immediately, with level of absorption that may vary over time- multiple dosages provide the effective daily dosage prescribed
- Not effective in dogs with incontinence due to neurologic disease or malformations
Ingredients
Instructions
FAQ
These Proin Chewable Tablets have the same efficacy as Proin Extended-Release Tablets.
Take control with PROIN
PROIN effectively treats urinary incontinence in dogs by strengthening the urethral sphincter muscle. Available in chewable tablets (25 mg, 50 mg, 75 mg), its liver-flavored formula makes administration easy and appealing to dogs and typically shows results within a few weeks, helping prevent accidents and restoring quality of life for both pets and owners.
Signs of Urinary Incontinence
- Dripping, leaking urine
- Wet spots where the dog sleeps
- Excessive licking of genitals
- Red, irritated skin in the genital area
About PROIN
PROIN (phenylpropanolamine hydrochloride) is indicated for urinary incontinence control due to urethral sphincter hypotonus in dogs, available in twice-daily chewable tablets. Ask your veterinarian before using PROIN with any other medications.
Important Safety Information
PROIN IMPORTANT SAFETY INFORMATION: The most commonly reported side effects were vomiting, loss of appetite, diarrhea, excessive salivation, agitation, tiredness, vocalization, confusion, increased water consumption, weight loss, weakness, fever, panting, and reversible changes in skin color (flushing or bright pink). Abnormal gait, seizures or tremors, as well as liver enzyme elevations, kidney failure, blood in urine and urine retention have been reported. In some cases, death, including euthanasia, has been reported. Sudden death was sometimes preceded by vocalization or collapse.
Instances of dogs chewing through closed vials of PROIN and eating the vial contents have been reported, in some cases resulting in overdose. Keep the product in a secured storage area out of the reach of pets in order to prevent accidental ingestion or overdose, as dogs may willingly consume more than the recommended dosage of PROIN Chewable tablets. Contact your veterinarian immediately if the dog ingests more tablets than prescribed or if other pets ingest PROIN Chewable tablets.
PROIN may cause elevated blood pressure and should be used with caution in dogs with pre-existing heart disease, high blood pressure, liver disease, kidney insufficiency, diabetes, glaucoma, and other conditions associated with high blood pressure.
The safe use of PROIN in dogs used for breeding purposes, during pregnancy or in lactating bitches, has not been evaluated. Contact your veterinarian if you notice restlessness or irritability, loss of appetite, the incontinence persists or worsens or any other unusual signs. See prescribing information for complete details regarding adverse events, warning and precautions.
Consumer Dog Owner survey conducted by PRN Pharmacal, December 2022 | 2025 PRN Pharmacal, Inc. All rights reserved.
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Customers Mention
Ease of Use
Effectiveness
Ingredients
Long-Term Benefits
1339 Customer Reviews
Worked Great & Cheaper Than Vet
Our Kinzei had been on Proin for years due to incontinence and it did all that it should have. She would only have issues with leaking when I'd forget to give her
Our Kinzei had been on Proin for years due to incontinence and it did all that it should have. She would only have issues with leaking when I'd forget to give her a dose. Being that they are chewable, I would have hoped she would have taken like a treat, but nope... being true to her Husky heritage, she made me work for it. We had her on auto shop and that was so convenient!! Unfortunately we had to put her down (14 years old, had a nice long and happily spoiled life) and just memorializing her profile on Chewy had them canceling future shipments so I didn't have to.
adopted after many surgeries
Our adopted dog, Tish, was brought to the shelter with tumors all over her vulva and teats. We think she was used as a breeder. After her surgeries she had trouble
Our adopted dog, Tish, was brought to the shelter with tumors all over her vulva and teats. We think she was used as a breeder. After her surgeries she had trouble holding her urine. When she laid down it would just run out. The vet prescribed this medication and two days after that she stopped having leakage and has been dry ever since.
Stops the urgency
Pinto Bean, a rescue dog, was spayed at too young an age missing out on the benefits of estrogen and as a result suffered with incontinence. Her vet put her on Proin
Pinto Bean, a rescue dog, was spayed at too young an age missing out on the benefits of estrogen and as a result suffered with incontinence. Her vet put her on Proin at 6 months old and it stopped the incontinence right away. She’s 5 now and takes 1/2 a pill daily, down from 1/2 a pill twice daily. Her vet said she may get to a point where she no longer needs Proin and that happened with Pinto Bean for a few weeks, but then her symptoms returned and she went back on it The 1/2 pill once a day keeps her from feeling uncomfortable so she’ll be staying on that dosage
Compassion and service
My dog passed after a big order. I called and your sweet staff immediately offered to return my funds. And THEN yesterday I received a beautiful heartfelt card
My dog passed after a big order. I called and your sweet staff immediately offered to return my funds. And THEN yesterday I received a beautiful heartfelt card and a painted rock with Kinder’s name on it. So far above what I ever expected! Wonderful people and you will be my goto for all future pets! Xxxx
Two-edged Sword
I hate giving this medication to my girl. But unfortunately she has a leaking problem due to her spay surgery when she was little. I hate the side effects so I give
I hate giving this medication to my girl. But unfortunately she has a leaking problem due to her spay surgery when she was little. I hate the side effects so I give her as little possible to maintain her quality of life. The medication works well! A lot of people swear by it and a lot of people swear about it. Chewy did an excellent job of getting the script filling it and getting it shipped out to us. I didn't calculate correctly and wound up being without medication for 4 days. My girl is a husky and you can tell she's absolutely embarrassed when she wakes up from a nap and she's wet. I just can't see her so sad and embarrassed that's why I continue giving her this medication.
Effective meds for incontinence
Bowie used Proin for manny years. She started having incontinence issue at around age 6. I would recommend it pet owners. Sadly Bowie passed away on Thursday this
Bowie used Proin for manny years. She started having incontinence issue at around age 6. I would recommend it pet owners. Sadly Bowie passed away on Thursday this week. She was 13. We were not able to use the new refill.
not my favorite but it works
I believe this medicine attributed to my dogs loss of appetite. He is a 70lb pit who loved to eat. So much so that i got him a slow feeder and had to pick up everyones
I believe this medicine attributed to my dogs loss of appetite. He is a 70lb pit who loved to eat. So much so that i got him a slow feeder and had to pick up everyones bowls when they were done. Now it is a chore to make him eat. Then trying to give him this pill is a nightmare. The smell is atrocious. The company definitely needs to come out with a new flavor/smell. Ive done peanut butter, wrapped in cheese of stuffed in meat, pill pockets you name it i tried it. Until recently a new vet told me since he's still active and not over weight to try cream cheese and holy moly that is the winner. Before i hated the mess on my hands with the peanut butter but now this is so worth it. If you have trouble with giving this pill to your dog i swear by it - GIVE IT WITH CREAM CHEESE! Just enough to coat it. They swallow it whole and you dont have to shove it down their throats.
Amazing effectiveness!
Our 15 year old beagle was peeing in her sleep and dribbling almost 3-4 times a day. It had become so stressful and frustrating to have to clean her blankets and
Our 15 year old beagle was peeing in her sleep and dribbling almost 3-4 times a day. It had become so stressful and frustrating to have to clean her blankets and bed constantly. We put diapers on her at night but they would always slip off or leak. My wife and I love her to death but at times we were reaching our breaking point. Vet put her on Proin and we saw immediate results! She has not had any accidents for over 2 weeks, and if she needs to go in the middle of the night she wakes us up like she used to. You don't understand how much stress you're under until it's gone. Now are little ole lady is living her best life in her golden years.
Easy process, great service.
Setting up an auto ship order for my girl, Winnie, was easy as can be. Just need to create an account, add the pet, choose “have Chewy contact vet” and it’s done
Setting up an auto ship order for my girl, Winnie, was easy as can be. Just need to create an account, add the pet, choose “have Chewy contact vet” and it’s done. First shipment arrived fast, well on time, and I love that you get a really nice discount on the first one!
Definately made my dog feel sick
PLEASE make sure you are in tune with your dog if you decide to try this. Many people are so happy something "works" that they ignore the signs of how it takes the
PLEASE make sure you are in tune with your dog if you decide to try this. Many people are so happy something "works" that they ignore the signs of how it takes the joy away from their dog. Or they just aren't in tune with their dog in the first place. This stuff "worked" but my dog most definitely did not feel well on it. I have learned to connect with my dog to the point where things that others around me don't notice I can see pretty easily. So I was able to see a big differance in how she was feeling. It worked pretty well on stopping the peeing, but I took her off it and she went right back to being herself. There was a big differance. I would rather deal with messes or pad train her than to make her feel nausea all the time and occasionally throw up (2x). She is so much happier off it. It's like life is worth living again for her. Your dog may be fine on it but I would encourage people to maybe look into something more natural first. Due to natural selection animals are so good at hiding how they feel that it's not hard to miss when they are feeling pretty crappy.