Interceptor Plus Chew for Dogs, 25.1-50 lbs, (Yellow Box), 6 Chews (6-mos. supply)

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About This Item

Details

  • Interceptor PLUS protects against more types of worms than other formulas
  • Tasty, monthly chicken-flavored chew with real chicken, making dosing easy
  • Prevents heartworm disease plus treats and controls adult hookworm, roundworm, whipworm and tapeworm infections
  • Covers worms commonly found in dog parks trails, backyards or carried by mosquitoes
  • Delivers protection for a full month Heartworm, hookworm, roundworm, whipworm and tapeworm

Ingredients

Instructions

FAQ

Learn More About Interceptor Plus From Our Team of Experts

About Interceptor Plus

Upgrade Your Heartworm Protection

Interceptor Plus (milbemycine oxime/praziquantel) combines heartworm disease prevention with the treatment and control of adult hookworm, roundworm, whipworm and tapeworm infections. It’s a once-a-month, chicken-flavored chewable that’s safe for puppies 6 weeks and older, weighing over 2 pounds.

Broad Spectrum Protection

Protect your dog against five different parasites with just one chew. Interceptor Plus prevents heartworm disease and controls hookworm, roundworm, whipworm, and tapeworm threats for a full month to help give you peace of mind on all your adventures. Each box contains stick-on labels for your calendar, making reliable, year-round protection easy to remember with a monthly reminder.

5 Parasites, One Easy Dose

The two powerful active ingredients in Interceptor Plus, milbemycin oxime and praziquantel, when used according to the label, provides safe and effective broad-spectrum protection against five types of dangerous worms. Make parasite protection one and done every month.

Tasty Chicken-Flavored Chew

Interceptor Plus comes as a tasty, chicken-flavored chew, accepted by 96.6% of dogs in a field study, so you won’t have to battle to get your pup to take his medicine. Dogs love it and pet parents appreciate the ease.Simply give Interceptor Plus to your dog by hand or by adding it to a small amount of dog food, and make sure your dog chews up and swallows the complete dose.

Product Guide

Interceptor Plus offers protection for dogs in most sizes and weights. Choose the option best suited for your furry friend.

2 - 8 LBS

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8.1 - 25 LBS

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25.1 - 50 LBS

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50.1 - 100 LBS

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Indication

Interceptor Plus prevents heartworm disease and treats and controls adult roundworm, hookworm, whipworm, and tapeworm infections in dogs and puppies 6 weeks or older and 2 pounds or greater.

Important Safety Information

Treatment with fewer than 6 monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention. Prior to administration of Interceptor Plus, dogs should be tested for existing heartworm infections. The safety of Interceptor Plus has not been evaluated in dogs used for breeding or in lactating females. The following adverse reactions have been reported in dogs after administration of milbemycin oxime or praziquantel: vomiting, diarrhea, decreased activity, incoordination, weight loss, convulsions, weakness, and salivation.
See Interceptor Plus product label for complete safety information.

About Interceptor Plus

Interceptor Plus was made to protect canine companions from five common parasitic health threats. Just one dose every month prevents heartworm disease and controls hookworms, roundworms, whipworms, and tapeworms in dogs. Dosing is easy with the chicken-flavored chews, and protection can be achieved year-round with monthly use. Give your dog Interceptor Plus to protect your best friend from these dangerous parasites. Interceptor is a trademark of Elanco or its affiliates. PM-US-20-1050
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4.8
Rated 4.8 out of 5 stars
3590 Ratings

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

93% Positive

Effectiveness

94% Positive

Ingredients

90% Positive

Long-Term Benefits

92% Positive

1045 Customer Reviews



Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 5 out of 5 stars
By Alexia on Aug 11, 2025

Prevention is key to health

Whip worms took my dog's life by causing an inoperable obstruction in the brain. Eating a simple monthly chew and she would still be here

Whip worms took my dog's life by causing an inoperable obstruction in the brain. Eating a simple monthly chew and she would still be here

By Alexia on Aug 11, 2025
Delyce
Delyce

Rated 5 out of 5 stars
By Nicolette on Jul 8, 2025
Charlie
Charlie

My vet recommended

All my other pups were just on heart guard. But when I found out that my sweet little girl had whip worm I asked my vet what did I do wrong? They said nothing it

All my other pups were just on heart guard. But when I found out that my sweet little girl had whip worm I asked my vet what did I do wrong? They said nothing it happens. Specially with pups that come from the south. Which my pup was rescued from. I asked if there was anything that would prevent this and they recommended this. Char is always been worm free of all the ones she could get. Plus heart worm. I recommend it and with future dogs use it.

By Nicolette on Jul 8, 2025
Charlie
Charlie

Rated 5 out of 5 stars
By MalMom5 on Feb 18, 2026
Top 250 Contributor
Envy
Envy

Safe and effective prevention

As always, I love how safe and effective Interceptor is. I never have to worry about any of my dogs becoming heartworm positive. And bonus, it seems to taste good

As always, I love how safe and effective Interceptor is. I never have to worry about any of my dogs becoming heartworm positive. And bonus, it seems to taste good too!

By MalMom5 on Feb 18, 2026
Top 250 Contributor
Envy
Envy

Rated 5 out of 5 stars
By Marc on Dec 14, 2018

Don’t get heart worm!

Milbemycin oxime and praziquantel. Yup, that’s what it is this pill my daddies give me once a month. I really don’t know what that stuff is but my daddies told

Milbemycin oxime and praziquantel. Yup, that’s what it is this pill my daddies give me once a month. I really don’t know what that stuff is but my daddies told me is to to prevent heart worm. And to tell you the truth, I know a little bit about heart worm cause before I was adopted by my daddies and came from Puerto Rico to live in Boca Raton Florida I heard that a lot of my cousin dogs had heart worm and that was not good. Not good at all. Just think about it: worms. And your heart? No way. Keep them out. Have your mommies or daddies get you this medicine and give it to you once a month. And stay healthy. And tell them to buy it at chewy.com cause it’s a very good price and then your mommies or daddies can buy more treats with the money they save and I like that. I like that a lot. But I like it more that I take this pill which is soft and chewy (haha) and I don’t get heart worm. Love from Boca Raton from Bori!

By Marc on Dec 14, 2018

Rated 5 out of 5 stars
By Iva on Sep 29, 2022
Top 500 Contributor

Interceptor Plus vs Sentinel Spectrum

Both contain Milbemycin (11.5mg) with Praziquantel (114mg) which besides heartworm disease prevention they treat and control intestinal parasites (adult whipworms,

Both contain Milbemycin (11.5mg) with Praziquantel (114mg) which besides heartworm disease prevention they treat and control intestinal parasites (adult whipworms, roundworms, hookworms and tapeworms ). Sentinel Spectrum contains additional Lufenuron (230 mg) which controls flea populations by breaking the flea lifecycle in both the egg and larval stages (but not adult fleas! For that you would need extra supplement). Tasha was on Sentinel Spectrum for more than a year but I have changed that for Interceptor Plus. We do not need the Lufenuron. The intestinal parasites control and treatment is the most important for us since Tasha would eat whatever she finds when she runs free in our wilderness. I got a coupon 20% off on prescription drugs but it excludes Sentinel Spectrum. I was glad since it made me to look into other options. Interceptor Plus is not only cheaper ( $50 )than Sentinel ( $64 ) but I also do not feed my dog with more unnecessary toxins-Lufenuron-which is not needed in our area. Chewy was amazing as always. I called about changing my autoship for this brand. The representative applied my coupon, contacted our vet and the new medication arrived within a week.

By Iva on Sep 29, 2022
Top 500 Contributor

Rated 5 out of 5 stars
By ArizonasMom on Mar 14, 2021

Best prices always

We shop around before making purchases to ensure we are being smart and saving where we can. Even on prescription meds, Chewy beats everyone else's price! Then

We shop around before making purchases to ensure we are being smart and saving where we can. Even on prescription meds, Chewy beats everyone else's price! Then you factor in their truly state of the art website, their customizable reordering process and overall FANTASTIC Customer Service, and perhaps you'll understand why if there were 6 stars, that would be my rating!

By ArizonasMom on Mar 14, 2021

Rated 5 out of 5 stars
By Adrienne on Jul 10, 2024

Tops as usual

It would take me a full book to tell you what I think of Chewy I love Chewy. My husband loved.Chewy. It started out with him doing the ordering .when my husband

It would take me a full book to tell you what I think of Chewy I love Chewy. My husband loved.Chewy. It started out with him doing the ordering .when my husband died in 2020, Chewy was right there with flowers, when my dog died and my pussycat died - Chewy was right there with more flowers and more love you can’t imagine! I love Chewy I live in Oregon and I still love Chewy so that’s why I said it would take me a whole big book to write about how much I love Chewy and their prices. I can’t get over their prices and I thank you because your people help me your pharmacist help me your employees help me and I really really really appreciate you all. Thank you so much.

By Adrienne on Jul 10, 2024

Rated 5 out of 5 stars
By Carol on Jul 13, 2019

Heart worm preventative

This was the first thing I found that my dog can take for heartworm that doesn’t make him crazy for 24 hours. He just can’t tolerate the heart guard. He doesn’t

This was the first thing I found that my dog can take for heartworm that doesn’t make him crazy for 24 hours. He just can’t tolerate the heart guard. He doesn’t seem to like that it’s a firm chewable though so I have to cut it up and put it in his food.

By Carol on Jul 13, 2019

Rated 5 out of 5 stars
By Alyssa on Jul 16, 2025
Sam Fluffy Blessant
Sam Fluffy Ble...

Easy auto renewal

I didn’t realize my pup was out of medication untill I got a shipment on my porch. I forgot that I had set meds on a 6 month auto renewal and I’m so glad I did!

I didn’t realize my pup was out of medication untill I got a shipment on my porch. I forgot that I had set meds on a 6 month auto renewal and I’m so glad I did! Sam Fluffy rates it 10/10

By Alyssa on Jul 16, 2025
Sam Fluffy Blessant
Sam Fluffy Ble...

Rated 5 out of 5 stars
By Karin on Jan 18, 2025

Only thing my two dogs can tolerate

My dogs do not tolerate any other heartworm product. They just can’t keep anything else down. They take the chews pretty well and I know that it’s very efficie

My dogs do not tolerate any other heartworm product. They just can’t keep anything else down. They take the chews pretty well and I know that it’s very efficient.

By Karin on Jan 18, 2025