Hill's Prescription Diet z/d Skin & Food Sensitivities Hydrolyzed Chicken Flavor Dry Dog Food, 25-lb bag

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About This Item

Details

  • Made in the USA, this recipe is formulated to help manage your furbaby’s food sensitivities.
  • It’s made without additives that are known to cause food allergies, helping avoid skin and digestive signs of adverse food reactions.
  • The recipe features highly hydrolyzed proteins that are broken down to avoid detection by the immune system.
  • It’s rich in omega-3 and omega-6 fatty acids to promote skin health and regeneration.
  • Continued feeding may help reduce the risk of adverse food reactions and promotes healthy skin and digestion.

Ingredient Information

Feeding Instructions

FAQ

Learn More About Hill's Prescription Diet From Our Team of Experts

About Hill's Prescription Diet Foods for Skin / Food Sensitivities

Improving Lives Together

Groundbreaking Nutrition for Sensitive Dogs

Dogs with skin and coat conditions or food sensitivities can benefit from Hill's Prescription Diet z/d and d/d foods. Prescription Diet d/d has limited ingredient nutrition and a single intact animal protein. The Prescription Diet z/d food features a highly hydrolyzed protein and a single carbohydrate source to minimize the risk of allergic reactions. Many pet parents discover that simply eating the right food helps eliminate food-related causes of skin irritation and helps avoid reactions to food.

Clinical Nutrition

With Hill's, it's not just high-quality ingredients that count. Their focus is on the proper balance of nutrients in every recipe. So Hill's has developed foods that are designed to help pets with specific health conditions, providing the right nutrients to support their health. Hill's alliance with veterinarians puts them in a unique position find a nutrition recommendation for your pet no matter what health issue your pet is facing.

Formulated by Veterinarians

Hill's Prescription Diet started with a veterinarian's belief that some health issues could be managed through nutrition. What began as a theory has now been proven through extensive research by a team of over 220 vets, PhD nutritionists and food scientists. The results can be seen in Hill's Prescription Diet therapeutic pet foods.

Meeting the Highest Standards

Providing a food that delivers exactly what it says it does is Hill's number one priority, in fact, they perform over five million safety and quality checks every year. They've established relationships with trusted suppliers and will only accept ingredients that meet stringent standards.

The Taste Factor

You might know that Hill's Prescription Diet is good for your pet, but she's only concerned with the taste. Even though they place a heavy emphasis on nutrition, Hill's hasn't forgotten about palatability. Savory ingredients are combined to produce foods with enticing aromas, textures, and shapes that your pet can't resist.

Find the Right Formula

Talk to your veterinarian about the right formula for your pet.

z/d Skin/Food Sensitivities

Original

Key Nutrients

  • Highly hydrolyzed animal protein
  • Single purified carbohydrate source
  • High levels of vitamin E
  • Natural fiber
  • Essential fatty acid enriched
  • Clinically proven antioxidants

Health Benefits

  • Visible skin and coat improvement in 30 days
  • Promotes healthy skin barrier
  • Helps support a healthy immune system
  • Clinically proven to help normalize stool

d/d Skin/Food Sensitivities

Potato & Venison

Potato & Duck

Potato & Salmon

Key Nutrients

  • Limited ingredient nutrition with single intact animal protein
  • No soy protein or gluten
  • High levels of omega-3 and 6
  • Clinically proven antioxidants

Health Benefits

  • Results you can see in the skin and coat
  • Helps maintain a healthy skin barrier
  • Helps improve digestion and stool quality
  • Supports a healthy immune system

Derm Defense

Chicken

Key Nutrients

  • With proprietary complex of bioactives and phytonutrients
  • High levels of omega-3 and 6 fatty acids
  • Clinically proven antioxidants, including vitamin E
  • No corn, chicken or by-product meal, artificial colors, flavors or preservatives

Health Benefits

  • Helps strengthen skin barrier
  • Drives healthy skin from within
  • Formulated to help soothe and nourish skin and coat
  • Helps skin to recover naturally
  • Holistic long-term solution supporting healthy immune system

About Hill's Prescription Diet

Hill's mission is to help enrich and lengthen the special relationships between people and their pet. Their Prescription Diet product line delivers clinically proven nutrition that supports common pet health concerns, from digestive and urinary health to aging and weight management.

Shop Hill's Prescription Diet

Questions & Answers

15 Customer Questions


How much taurine is in this food?


Does this help prevent itching?

Answer by ChewyOct 14, 2024
This recipe is formulated to eliminate food-related causes of skin irritation and results in a visible improvement of the skin and coat.

How many cups are in the 25 pound bag?

Answer by ChewyNov 24, 2025
There are roughly 35.44 cups in an 8-pound bag, 77.97 cups in a 17.6-pound bag, and 110.75 cups in a 25-pound bag.

Can you add water to this to this dry food to turn it into a wet food consistency?

Answer by ChewyJun 26, 2024
Water can be added to this formula for palatability purposes.

4.5
Rated 4.5 out of 5 stars
3901 Ratings

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

84% Positive

Effectiveness

81% Positive

Ingredients

83% Positive

Long-Term Benefits

86% Positive

1826 Customer Reviews



Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 5 out of 5 stars
By michelle on Feb 16, 2025

NO MORE Ear & Skin Infections in Chocolate Lab

Wow! Let me just say our guy was on a very expensive all age inclusive dog chow when we got him @ 8 weeks @ he suffered from chronic ear infections. Like constant

Wow! Let me just say our guy was on a very expensive all age inclusive dog chow when we got him @ 8 weeks @ he suffered from chronic ear infections. Like constant. I tried raw, I made my own, we bought $100 20lb bags that touted they were best only for him to not like and refuse to eat. We tried all kinds of formulas and meds and what not. Then we moved and went to a new vet. She told us to try this. OMGosh! The past 2 years have been Heaven on this food. He’s now 4 and rarely gets ear infections. Maybe 2 in that time but it’s from swimming in ocean. Also helped him with the weird white film he would get on his toenails that looked like a film of some sort. His feet still smell like doritos at times but nothing like the yeasty smell he use to have.

By michelle on Feb 16, 2025

Rated 5 out of 5 stars
By Emerson on Aug 26, 2024

Don’t believe the influencers

Arlo has IBD. It has been absolutely heartbreaking to watch. For the first year of his life I bought all the garbage online saying raw is best and corn it killing

Arlo has IBD. It has been absolutely heartbreaking to watch. For the first year of his life I bought all the garbage online saying raw is best and corn it killing your dog. Turns out their unscientific advice is what was hurting my boy. Science, my vet and my own experience prove this food is effective and not only healthy, but fantastic. Please don’t be swayed by the unscrupulous influencers who would rather sell you a diet guide then tell you to listen to your vet. Arlo isn’t totally symptom free, but I don’t come home to a kennel soaked in hemorrhagic diarrhea or watch him throw up 5 times a day and he’s finally a healthy weight. Apparently corn isn’t so bad after all.

By Emerson on Aug 26, 2024

Rated 5 out of 5 stars
By Tracy on Nov 12, 2025

Delivery disappointed

I tried giving only 2 stars but apparently Chewy doesn’t like honesty. Most delivery companies leave our orders by the garage (UPS and FedEx) but this company OnTrac

I tried giving only 2 stars but apparently Chewy doesn’t like honesty. Most delivery companies leave our orders by the garage (UPS and FedEx) but this company OnTrac went through our front gate to our front door instead. Our front yard is containment for our dogs. Luckily they were inside but this guy had to literally unlock our gate and open it to get inside but when he left, he left the gate wide open. Not knowing that we even got our delivery (no knock or anything) didn’t think I had to worry about the gate being open. I went to take my dogs outside for their potty break and our rescue dog ended up running out the gate the guy left open. We had to go searching for her and we aren’t young people so it wasn’t easy getting her back. Please remind your delivery companies you use that if they go through the trouble of opening a closed gate, close it on their way out

By Tracy on Nov 12, 2025

Rated 2 out of 5 stars
By Lee on Jan 22, 2026
Mila
Mila

Anyone notice recent (2026) changes?

Let me start off by saying, I know they changed their formula sometime last year, even though it wasn’t widely announced and I only found out from reading these

Let me start off by saying, I know they changed their formula sometime last year, even though it wasn’t widely announced and I only found out from reading these reviews on Chewy (thanks, y’all). I still fed my girl both the canned and dry versions anyway, because my options are very limited since RC hydrolyzed food doesn’t agree with her. After a while, I noticed she wasn’t eating much of the canned food I gave her with her dinner, so I just kept getting the dry. And she was fine with that until this month, when I noticed her gastro/inflammation symptoms were back and she stopped eating the dry food. So I had to throw the rest of the bag away and start using her mix-in (Shepherd Boy Farms fish flavor) as her full daily meal. As expensive as HS prescription food is, the amount of SBF food needed to sustain her at a healthy weight is even more expensive. So I’m stuck. I have to go back to the HS z/d kibble. I’m just confused and frustrated. I hate that my dog is reliant on this food and it can all be messed up depending on any changes they decide to make on their end. Changes that I might never even know about.

By Lee on Jan 22, 2026
Mila
Mila

Rated 1 out of 5 stars
By Kayln on Mar 7, 2025

This dog food is HORRIBLE!!!

We have a 12 year old Pomeranian (Dexter) with diabetes and pancreatitis. We took him to an internist Vet who told us that his triglycerides were waay too high so

We have a 12 year old Pomeranian (Dexter) with diabetes and pancreatitis. We took him to an internist Vet who told us that his triglycerides were waay too high so she recommended this food. The moment we started this Z/D formula, Dexter started experiencing an uncontrollable bladder and chugging large amounts of water. We took him to the vet for an assumed UTI and even after antibiotics he was stilling urinating uncontrollably. We started assuming the worst for him, started doing expensive vet tests for Cushing's Disease. Purely by chance, we gave this food to our other 12 year old Pomeranian (Zuko, who is a picky eater) one evening. The ENTIRE night Zuko was getting up from bed every hour to chug lots of water. So we switched Dexter back to his old food and already he is back to normal, no more bladder control problems or chugging large amounts of water. So be warned, this food may have terrible effect on your dog. I just wanted to put a heads up out there for anyone else who might experience this sort of problem and we only found out it was the food because we gave it to our other healthy dog.

By Kayln on Mar 7, 2025

Rated 5 out of 5 stars
By Kathleen on Jan 23, 2024

My big guy loves it!

*LENGTHY FOR A REASON, HOPE THIS HELPS* My vet had stuck my, now, 7mo English Mastiff, Sampson, on this food due to severe itching. He's been on this food for

*LENGTHY FOR A REASON, HOPE THIS HELPS* My vet had stuck my, now, 7mo English Mastiff, Sampson, on this food due to severe itching. He's been on this food for about 4 months. He had severe itching problems due to some allergy. We couldn't test to see what allergy he had, due to him being so young at the time, so my vet gave us this food as a last resort. He loves this food and shovels it down! Yes it is very expensive, but I would rather my dog eat this food, than go on expensive medications that could kill him. Since being on this food, his itching is pretty much completely gone, he gets lots of compliments on how soft his coat is, and is so much happier now that he's gotten relief. I'm extremely grateful to our Vet for suggesting this food. With all this being said, I understand this food may not work for everyone's pups, but I wanted to write this review in hopes someone might find it useful. I tried everything. He started on Purina One Chicken and Rice Formula Large Breed Puppy. Then we switched to Purina One Pro Plan Sensitive Skin and Stomach Salmon. Then we tried Hills Science Diet Lamb, and finally gave this a try, along with antihistamines and an isolation diet, and by the grace of God, it worked! I recommend this if your pup is having allergies and is biting, scratching, and chewing themselves to death, at least try this food. I hope everyone's pups are healthy! Also Chewy did a fast job on delivering it. Usually if I order anything it takes 3ish days. His food got here in 2 days, which is great, because he was running out.

By Kathleen on Jan 23, 2024

Rated 1 out of 5 stars
By Erica on Feb 20, 2026

New formula brought back issues

I have fed Hill’s Prescription Diet z/d to my dog for years due to severe food allergies and chronic skin issues. It was one of the only diets that consistently

I have fed Hill’s Prescription Diet z/d to my dog for years due to severe food allergies and chronic skin issues. It was one of the only diets that consistently kept him comfortable and stable. Since the recent formula update, his symptoms have noticeably worsened. I have observed a significant increase in skin flare-ups, itching, ear infections, hair loss, and overall sensitivity. My dog has a long medical history of allergies and immune-related skin conditions, so even small ingredient adjustments can have major consequences. For healthy dogs, minor formulation changes may not matter but for dogs with compromised immune systems, consistency is critical. Prescription diets are not simply “food” they are part of ongoing medical management. Because this diet is designed specifically for highly sensitive dogs, formula changes especially involving added fibers or digestive blends can have unintended consequences for pets who rely on ingredient stability. I strongly encourage clearer and more proactive communication when updates are made to therapeutic diets. Many of us depend on consistency for our pets’ health and quality of life. Very disappointed

By Erica on Feb 20, 2026

Rated 5 out of 5 stars
By Olga on Jun 25, 2025

100% works!

Recently adopted a German Shepard mix from the shelter. He was scratching, itching & biting 24/7! It was the saddest thing to see. He was miserable. Took him for

Recently adopted a German Shepard mix from the shelter. He was scratching, itching & biting 24/7! It was the saddest thing to see. He was miserable. Took him for his 1st vet appt and the Dr. had us switch to this dog food. Did the 7 day progression & I can’t believe the difference we are seeing. Around day 3 of 100% on this new food the skin irritation was 95% better! Our pup had the worst dandruff & that’s about 90% cleared up now. The food is expensive, yes but it does work. I will happily pay more to see this new addition to our home happy & healthy. As for his stool, I didn’t see any change other than a bit darker because the food is darker. We do add a bit of water to help rehydrate it- the pup must love the taste because he now watches me prepare and eats immediately. For anyone it doesn’t work for, I’m sorry & I hope you find something that does because I truly understand how upsetting it is to watch your dog suffer from allergies & skin irritations.

By Olga on Jun 25, 2025

Rated 5 out of 5 stars
By Andrew on Apr 6, 2025

It actually worked.

Both of my dogs had been struggling with allergies for the entire winter. One of them had developed Cushings as well. By the second bag, I started seeing the difference

Both of my dogs had been struggling with allergies for the entire winter. One of them had developed Cushings as well. By the second bag, I started seeing the difference. Now, only one dog eats this. The other dog gets the prescription Science Diet. They are like different dogs, especially the one on the prescription science diet. Don’t let the price deter you. It’s SO worth it to watch my dogs get comfortable in their own skin without the constant scratching.

By Andrew on Apr 6, 2025

Rated 1 out of 5 stars
By Tommy on Aug 18, 2025

Extremely Disappointed with Formula Change

I’ve relied on Chewy for years, but I’m extremely disappointed that you didn’t notify me about the formula change in Hill’s Prescription Diet z/d. My dog has IBS

I’ve relied on Chewy for years, but I’m extremely disappointed that you didn’t notify me about the formula change in Hill’s Prescription Diet z/d. My dog has IBS and depended on the old formula; this new version caused an immediate allergic reaction and sent us to the vet. Customers should be warned about major changes like this, especially with prescription diets. I’m returning the product and canceling my Autoship immediately.

By Tommy on Aug 18, 2025