Frontline Shield Flea & Tick Treatment for Medium Dogs, 21 - 40 lbs, 3 doses (3-Month Protection)

$36.74 First Time Autoship Price
this order
Save 30% (up to $30) today when you set up Autoship. 

$49.86 Autoship Price
(-5%) future orders
  • Keep saving 5% on every order
  • Get deliveries on your schedule
  • Skip, change, or cancel anytime
$52.48 Chewy Price
($17.50 /ea)
Save $7.51 (-13%)
$59.99 List Price
Promo, Spend $100, Get $30 eGift Card with code SUMMER
Promo, New Customers Only: Spend $49+, get $20 eGift Card + free shipping with code WELCOME

In Stock
FREE 1-3 day delivery
Free 365-day returns

No Interest if paid in full in 6 months on PayPal purchases of $149+. .

About This Item

Details

  • Helps kill ticks, stable flies, chewing lice and adult fleas, flea eggs and larvae.
  • Topical solution helps to repel ticks that may transmit Lyme disease and mosquitoes that may transmit heartworm disease.
  • Helps prevent reinfestation by stopping all flea life stages from developing.
  • Each dose is formulated to protect your dog for a full 30 days.
  • The treatment is easy to apply and is waterproof 24 hours after application.

Ingredients

Instructions

Size

FAQ

Learn More About Frontline Shield From Our Team of Experts

One-Spot Topical Application

Frontline Shield for Dogs is a topical solution that's available without a prescription. From a leading name in flea and tick protection, Frontline Shield is waterproof after 24 hours. 1 dose = 30 days of protection.

Flea, Tick, and Mosquito Facts

  • Fleas and ticks are a year-round threat.
  • They can be brought inside by people or dogs.
  • Fleas, ticks, and mosquitos can transmit harmful parasites and diseases.
  • Just one mosquito bite can spread heartworm disease, causing lifelong damage.

Proven 3-In-1 Protection

Frontline Shield has three active ingredients (permethrin, pyriproxyfen, and fipronil) that kiII fleas and ticks, inhibit egg and larval development of fleas, and repel ticks that may transmit Lyme disease and mosquitoes that may transmit heartworm disease.

How to Apply

Follow these simple steps for a correct and effective application:

  1.  Cut the tip of the pipette with a pair of scissors.
  2.  Part hair and apply on shoulder blades, completely emptying the pipette.
  3.  Leave the protection to spread through your dog's coat.

About Frontline Shield

Frontline Shield for Dogs is a 3-in-1 topical solution that kiIIs fleas and ticks, plus repels ticks that transmit Lyme disease and mosquitoes that transmit heartworm disease. Each dose lasts for 30 days, delivering the lasting protection your dog needs.

Shop Frontline Shield

Questions & Answers

4 Customer Questions


Does this kill fleas, ticks, flies, and mosquitos before they bite the dog?

Answer by ChewyMar 21, 2021
This treatment kills fleas, ticks, and chewing lice as well as repels mosquitoes, ticks, and stable flies.

can two dogs take this

Answer by BostonTerrierLadyApr 12, 2023
Yes, you can administrator it to more than one dog as long as you have enough medication for both animals

Is this product safe for a 4 month old puppy weighing 22 lbs

Answer by ChewyJul 04, 2021
This treatment is suitable for dogs 9 weeks of age and older, within the corresponding weight range.

Do you still need to give heartworm medication with this?

Answer by ChewyJun 17, 2026
This treatment protects against fleas and ticks, it does not protect against heartworms. Please consult with your veterinarian for further guidance.
4.3
Rated 4.3 out of 5 stars
243 Ratings

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

67% Positive

Effectiveness

67% Positive

Ingredients

69% Positive

Long-Term Benefits

67% Positive

70 Customer Reviews



Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 1 out of 5 stars
Verified Purchase
By Michele on Aug 3, 2025

Bad reaction

I put the medicine on my Jack Russell terrier, and it caused irritation in the treatment area. She would shake her head constantly. If I petted her where the medicine

I put the medicine on my Jack Russell terrier, and it caused irritation in the treatment area. She would shake her head constantly. If I petted her where the medicine was placed she would lean weirdly as if the skin were irritated. Just by looking at her, you could tell it bothered her. I have bathed her and washed the treatment area a few times with the hopes of clearing away the pain. I will never use liquid flea medicine again. I would love to have my money refunded, and I will probably toss the remaining treatments. How could I give that pain to another furbaby?


Rated 5 out of 5 stars
Received Free Product
By Sherridal on Nov 25, 2023

Highly recommend this flea treatment

My Staffie Maggie has been on flea medication monthly since we adopted her from the Humane Society 6 years ago. I had been purchasing an expensive monthly flea treatment

My Staffie Maggie has been on flea medication monthly since we adopted her from the Humane Society 6 years ago. I had been purchasing an expensive monthly flea treatment for her but the way she loves to roll around in the grass, occasionally she will get fleas. I love this product. It’s not as expensive and…NO fleas. I’m pleasantly surprised. I will definitely be purchasing this for Maggie every month over the expensive, top rated medication that I was using only for it to be hit or miss if it would work each month. I do want to mention Maggie has very sensitive skin due to her “rolling” in the grass/sand in our yard and she is bathed about 3x/month. She has extreme allergies.


Rated 5 out of 5 stars
Verified Purchase
By Michelle on Nov 29, 2025

Easy to use

This has been successful so far with warding off fleas and ticks. Dog isn't bothered by the process, slight smell or oil down his back. Comes with stickers to keep

This has been successful so far with warding off fleas and ticks. Dog isn't bothered by the process, slight smell or oil down his back. Comes with stickers to keep track of when to do the next dose on your calendar. So far, so good!


Rated 3 out of 5 stars
Received Free Product
By Toots on Dec 10, 2023

Just ok

This product is a liquid that has to be placed on the skin. It’s a little messy as we have inside dogs. I like other products that are in a pill form. I think it’s

This product is a liquid that has to be placed on the skin. It’s a little messy as we have inside dogs. I like other products that are in a pill form. I think it’s effective, but has to be reapplied every month.


Rated 5 out of 5 stars
By PupLuv on Sep 6, 2022

Works great!

It's been a while since I've had a dog and wasn't sure which flea & tick prevention to use on my puppy. I did my research on Chewy and decided to give Frontline

It's been a while since I've had a dog and wasn't sure which flea & tick prevention to use on my puppy. I did my research on Chewy and decided to give Frontline Shield a try. Fleas & ticks gross me out so I wanted to be sure and get him started when he was old enough and keep up with it every month. So far so good! Also like that it helps with mosquitoes - I don't like them biting me so it makes sense he wouldn't either!


Rated 1 out of 5 stars
Received Free Product
By somitche on Dec 5, 2023

Negative Reaction to Product

I hate to leave a bad review, but I have to be honest here. I have used Frontline in the past with all of my animals (dogs/cats) and was a huge fan. Unfortunately,

I hate to leave a bad review, but I have to be honest here. I have used Frontline in the past with all of my animals (dogs/cats) and was a huge fan. Unfortunately, this extra strength product was too much for my 30lb Brittany. Within 24 hours she was scratching nonstop and the area where the product was applied was completely red and inflamed. After 48 hours of this I decided to bathe her and she is now back to her normal behavior (not scratching).


Rated 5 out of 5 stars
Received Free Product
By Ashley on Dec 8, 2023

Keeps the bugs at bay!

I have tried other topical products before and have had mixed results but this one delivered. It wasn’t greasy, it kept the bugs off my dog during hikes and seemed

I have tried other topical products before and have had mixed results but this one delivered. It wasn’t greasy, it kept the bugs off my dog during hikes and seemed to keep them off for the entire month.


Rated 2 out of 5 stars
Verified Purchase
By Joan on Dec 11, 2025

Delays and confusing responses

I will not be buying meds from Chewy again. This order took way too long. And, while I waited for it, Chewy told me they had no record of it!!!

I will not be buying meds from Chewy again. This order took way too long. And, while I waited for it, Chewy told me they had no record of it!!!


Rated 1 out of 5 stars
Verified Purchase
By Robert on Mar 31, 2026

New shipping co. On trac destroying packages

My self and 2 friends have been getting crushed boxes from by out new shipping co. I saw Delivery guy just take package and throw over gate but you can tell damage

My self and 2 friends have been getting crushed boxes from by out new shipping co. I saw Delivery guy just take package and throw over gate but you can tell damage was done before that. So you've lost 2 Customers and now I'm going to order somewhere else too because you probably tried to save money with a shipper that destroys every package. And its been like this on 3 different orders for myself and 2 friends.


Rated 2 out of 5 stars
Verified Purchase
By Christy on Apr 3, 2026

Terrible packing

The item itself works well. This review is in particular to how this item was packaged in the last shipment. The box of flea and tick treatment was underneath two

The item itself works well. This review is in particular to how this item was packaged in the last shipment. The box of flea and tick treatment was underneath two dozen cans of prescription canned food. The box was completely smashed up for this reason. The plastic containers look undamaged at least.