Frontline Plus Flea & Tick Spot Treatment for Cats, over 1.5 lbs, 6 Doses (6-mos. supply)

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About This Item

Details

  • Promotes fast-acting, long-lasting protection from fleas and ticks.
  • Formulated with two active ingredients to help disrupt the flea life cycle and prevent new infestations.
  • Purr-fect for cats and kittens ages eight weeks or older weighing 1.5 pounds or more.
  • Works to kill adult fleas, flea eggs, flea larvae, chewing lice and ticks.
  • Waterproof protection means your pal can still enjoy their favorite outdoor activities and regular grooming routine.

Ingredients

Instructions

Size

FAQ

Learn More About Frontline Plus From Our Team of Experts
Important Information

Fleas rise to the top of your pet's coat as they die, so consider it a triumph if you start seeing more fleas at first, after treating your pet. If you’re still seeing fleas after application, it may be because your pet has picked up new fleas from the environment, which may include other pets, surfaces and outdoor areas. It may take up to 90 days to break the entire flea life cycle. Additionally, you should also treat sources of new fleas (i.e., carpet, yard, etc.) to ensure complete flea control.

Fast-Acting, Long-Lasting Protection

Frontline Plus is formulated with two active ingredients that kill fleas and ticks and prevent new flea infestations from developing. It’s waterproof 24 hours after application, lasts for a full 30 days, and comes in formulas for cats or dogs.

Easy One-Spot Topical Application

Frontline Plus is a spot-on solution that’s available without a prescription. 1 dose = 30 days of protection.

Protects Your Pet

  • Starts killing fleas and ticks fast and protects against reinfestation.
  • Waterproof for a full 30 days starting 24 hours after application.
  • Monthly dosing keeps your cat protected for every season.

How to Apply

Follow these simple steps for application:

  1. Hold upright with foil side toward you and snap applicator tip.
  2. Part hair and apply on shoulder blades, completely emptying the pipette.
  3. Leave the solution to spread through your pet's coat.

About Frontline Plus

To ensure your cat stays protected from fleas and ticks all year round, treat them monthly with Frontline Plus. This simple, easy, one-spot topical solution helps keep your pet free from infestations, providing you with peace of mind.

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Questions & Answers

48 Customer Questions

I've treated my 4 kittens 2mos. now, but I'm still seeing a lot of fleas and a TON of eggs. I'm talking, within 10 min of them laying on a black cloth, it's covered with eggs(looks like I dropped the salt shaker!) Will the eggs hatch? I'm contantly vacuuming but I'm still very concerned.

Answer by Stark • Aug 09, 2025
You also need to treat the environment with an environmental spray, wash all that can be washed in hot water, and keep up on the flea treatments. We've been told by our vet that most cats can be treated every 3 weeks for a bad infestation. Consult your vet before doing so though.

what kind of ticks does it kill

What age do you start flea treatments I have a 6 week old

Answer by 1ZITI1 • Aug 06, 2025
2 months old(8 weeks) and they also must weight at least 2.5 pounds

My cat is 18 lbs. will this be effective?

Answer by Chewy • Jan 30, 2026
The Frontline Plus Flea & Tick Spot Treatment for Cats, over 1.5 pounds will be effective for cats that weigh 1.5 pounds and up.
Reviews
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4.2
Rated 4.2 out of 5 stars
9061 Ratings
Terms & Conditions

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

73% Positive

Effectiveness

71% Positive

Ingredients

70% Positive

Long-Term Benefits

73% Positive

3829 Customer Reviews

Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 1 out of 5 stars
By DeAnn on Mar 28, 2026

Serious Concerns

I applied the repellent on Saturday, March 14, 2025. I noticed on Wednesday, March 25th, that Roxy was not eating. I thought she was finicky. I could not find her

I applied the repellent on Saturday, March 14, 2025. I noticed on Wednesday, March 25th, that Roxy was not eating. I thought she was finicky. I could not find her after that until mid-morning on Friday, the 27th. The first thing I did was try to feed her. She still would not eat. I then realized she was sick. I got her to the vet by 2 P.M., and her blood test showed she had Bobcat Fever from a tick bite. I placed my trust in the product, and now my cat is at the vet's office, he is trying to save her. This is terrible, and I hope she survives. Not only that, I know this is going to cost me hundreds of dollars, which I cannot really afford. Now I am afraid to ever use this again. I have one other cat that goes outdoors, and she so far is not affected. Thank goodness. However, I am stumped about which preventive care I should continue. I can only afford so much, and these cats are rescues that would not have had a home if I did not take them in. I am so saddened by this. Please pray Roxy makes it through.

Rated 4 out of 5 stars
By Barbara on Apr 2, 2026

Flea and tick drops

I’m never a fan of having to put any of this stuff on my pets. This is why it only got a four it is effective though I’ve had no negative problems with this product

I’m never a fan of having to put any of this stuff on my pets. This is why it only got a four it is effective though I’ve had no negative problems with this product. I only gave it four star because I don’t like to put it on

Rated 5 out of 5 stars
By Barbara on Jan 26, 2026

Service

I will never use a different pet supplier for food and/or supplies. I’ve been with them for years. Anytime I’ve had an issue that I couldn’t seem to resolve online

I will never use a different pet supplier for food and/or supplies. I’ve been with them for years. Anytime I’ve had an issue that I couldn’t seem to resolve online I only needed to make a phone call. Their res are attentive, respectful and knowledgeable. Also, they are my go-to at Christmas. Our family does notexcange gifts with adults - only kids and pets. They offer any kind of food imaginable and also have a large selection of toys and other supplies. I believe they also honor Rx spies. I have an auto order set up at regular deliveries which I can alter anytime. Shopped around occasionally, only to learn Chewy is the best to deal with! Highly recommend.

Rated 1 out of 5 stars
By Susan on Apr 2, 2026

Fleas

This Frontline flea medication didn’t work at all and Casey & Taffy are strictly indoor cats! I’ve tried everything! The Seresto collars were the best but then stopped

This Frontline flea medication didn’t work at all and Casey & Taffy are strictly indoor cats! I’ve tried everything! The Seresto collars were the best but then stopped working also. What next??

Rated 1 out of 5 stars
By Nymm on Jan 22, 2026

Bad formula and manufacturing

Having the same problems as everyone else apparently. The packages of treatment are leaking so about half of the product in every package I've received in recent

Having the same problems as everyone else apparently. The packages of treatment are leaking so about half of the product in every package I've received in recent months was wasted. And then in this past summer, after several years of using this brand religiously, my cats both got fleas and it was bad for months, even with hundreds of dollars of professional and self done flea treatments of the entire house and continued use of this product for prevention. Not buying again.

Rated 4 out of 5 stars
By Daniel on Mar 3, 2026

Might not work anymore in Northern California foothills?

Read reports that not all the brands work anymore in the Sacramento area, this might be one of them. In the past pets seemed to stay flea and tick free, but in the

Read reports that not all the brands work anymore in the Sacramento area, this might be one of them. In the past pets seemed to stay flea and tick free, but in the last few winter months the treatment doesn't seem to work as effectively anymore.

Rated 5 out of 5 stars
By Rosemary on Feb 1, 2026

Price, consistently works.

I have tried many flee treatments. This one works consistently, my cats are indoor/ outdoor. They roam daily over a large 5 acre grassy property. I have 3 cats

I have tried many flee treatments. This one works consistently, my cats are indoor/ outdoor. They roam daily over a large 5 acre grassy property. I have 3 cats of different ages and sizes Maine coon, blue Russian and a small runt. It has worked consistently for over a decade. My vet has suggested a few others over the years. I tried a few of the vets and none worked. Frontline A +

Rated 1 out of 5 stars
By Susan on Mar 5, 2026

Incorrect item

I was sent Dasuquin joint treats (which retails for $18) instead of the product I actually purchased (which retails for over $60). Very disappointed with this service

I was sent Dasuquin joint treats (which retails for $18) instead of the product I actually purchased (which retails for over $60). Very disappointed with this service and will not be utilizing chewy.com again.

Rated 5 out of 5 stars
By Janet on Mar 12, 2026

Effectiveness

Scout is our outdoor cat and he is a rescue. We want him to be protected from fleas and ticks and Frontline Plus keeps them off of him. We’re very pleased with how

Scout is our outdoor cat and he is a rescue. We want him to be protected from fleas and ticks and Frontline Plus keeps them off of him. We’re very pleased with how well it works. Would highly recommend this product!

Rated 5 out of 5 stars
By Merri on Mar 25, 2026

Love everything about Chewy

My dogs get so excited when they get mail. Chewy always gets the order right, they are helpful when you call in and talk to a person who understands. The kindness

My dogs get so excited when they get mail. Chewy always gets the order right, they are helpful when you call in and talk to a person who understands. The kindness is priceless.