Fluoxetine (Generic) Oral Solution, 20 mg/5mL, 4-oz bottle

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About This Item

Details

  • Used in the management of certain behavioral disorders
  • Helps address separation anxiety and compulsive behaviors
  • Contains fluoxetine
  • Selective serotonin reuptake inhibitor (SSRI)
  • Increases serotonin activity in the central nervous system

Ingredients

Instructions

FAQ

Learn More About Fluoxetine From Our Team of Experts
4.0
Rated 4 out of 5 stars
97 Ratings

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

75% Positive

Effectiveness

82% Positive

Ingredients

74% Positive

Long-Term Benefits

90% Positive

57 Customer Reviews



Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 1 out of 5 stars
By Erika on Sep 16, 2024

Different manufacturer, bad taste

Unfortunately the fluoxetine that arrived was from a different manufacturer than was pictured, so if course it was a different flavor. My cat tolerated the "cherry"

Unfortunately the fluoxetine that arrived was from a different manufacturer than was pictured, so if course it was a different flavor. My cat tolerated the "cherry" flavor that we'd been getting from the vets office, but this other manufacturer uses mint flavoring and that was a huge no. Gagging, spitting, hissing, bubbling at the mouth. Chewy refunded me which is great customer service, 5 stars for them, but 0 stars for the actual med unfortunately.


Rated 3 out of 5 stars
By Jane on May 19, 2020

Results Less Than Needed

Our vet recommended Fluoxetine to help our recently rescued kitty adjust to her new home and companion cat (both of whom are 9+ years old). She had been in four

Our vet recommended Fluoxetine to help our recently rescued kitty adjust to her new home and companion cat (both of whom are 9+ years old). She had been in four places (original owner died, family member adopted but surrendered to city shelter in less than a month, then was saved by a local rescue) before we adopted her. While we followed the recommended protocol for introducing her to our other cat, she was extremely aggressive at every opportunity. Our house is an open floor plan so areas that can be closed off are limited. Using a baby-gate at the doorway was marginally successful but she managed to slip through it several times and immediately went into attack mode, howling and screeching. We had tried a number of other products (Feliway, Rescue Remedy, ComfortEze, etc.) with no success. This is week #4 on Fluoxetine. Yesterday, after seeing our other cat sitting on the stairs, she used her body weight to pry open the baby gate in order to get through, run down the steps, and attack him. Our vet has told us that if the Fluoxetine does not work, she may “need to be an only cat.” We are already attached to her and cannot bear the thought of giving her up. In addition, the concept of making her adapt to yet another new home is very upsetting. We are hoping that continued use of Fluoxetine will have the desired effect.


Rated 5 out of 5 stars
By Georgia on Oct 23, 2025

Price is unbeatable!

I was having trouble getting the prescription from another online pharmacy so my vet found a pharmacy in town to get it filled, in the meantime I went onto Chewy

I was having trouble getting the prescription from another online pharmacy so my vet found a pharmacy in town to get it filled, in the meantime I went onto Chewy and you had it. It was fast and 1/2 the price of the other two pharmacies. Half the price and fast delivery, win-win for my kitty!


Rated 5 out of 5 stars
By Jo on Mar 13, 2022

Great product

The rescue group I got Frankie from suggested this. Frankie is a young blind neurological dog. He is a holy terror and also can be vicious. This medicine was recommended

The rescue group I got Frankie from suggested this. Frankie is a young blind neurological dog. He is a holy terror and also can be vicious. This medicine was recommended for him and it really calmed him down. Sadly we had a trainer who should stick to training and not tell how to administer medicine. We slowly cut down the dosage and eliminated it for one day and knew he will have to be on it the rest of his life. We increased back to one dose per day rather than 2 and he seemed fine with it until today. We will be putting him on 2x per day. It makes him into a very sweet dog. He is a foster failure.


Rated 5 out of 5 stars
By Elly on Aug 2, 2023

Anxiety for Cats

My cat had been spraying really bad everywhere no matter what we did. He is neutered, we tried Feliway, we tried relaxing treats and sprays, we were always on top

My cat had been spraying really bad everywhere no matter what we did. He is neutered, we tried Feliway, we tried relaxing treats and sprays, we were always on top of cleaning his litter box, but he wouldn’t stop no matter what. My vet prescribed fluoxetine to give him every night and the spraying stopped! He stopped being so anxious all the time and stopped marking everywhere. It was a miracle! I ran out once and he wasn’t on it for a while and he started spraying again. So I can say that this is definitely the thing that stopped him spraying! 10/10 recommend


Rated 4 out of 5 stars
By Nancy on Mar 26, 2025

Timely delivery

Frustrated that this is the second bottle I ordered that did not include an adapter to draw the solution into a syringe.

Frustrated that this is the second bottle I ordered that did not include an adapter to draw the solution into a syringe.


Rated 5 out of 5 stars
By Laura on Nov 29, 2023

Works Great!

My cat started spitting out pill pockets so we tried adding this to his wet food. He’s stopped to sniff it once but still eats it all up! NOTE: does not come with

My cat started spitting out pill pockets so we tried adding this to his wet food. He’s stopped to sniff it once but still eats it all up! NOTE: does not come with a syringe! (or maybe it was just missed in my order). Still giving 5 stars as it's easy enough to get a syringe from your pharmacy or vet, but it'd be nice if one was provided. The medicine has a cherry flavor and i suspect he wouldn't like it without food, but masking it with wet food works great :)


Rated 3 out of 5 stars
By Cheryl on Jan 23, 2026

Hoping the medication does work because the taste is not great.

This comes in an oil base and it's in a big bottle. The taste must be absolutely horrendously awful based upon my cats reaction to it, and there is absolutely nothing

This comes in an oil base and it's in a big bottle. The taste must be absolutely horrendously awful based upon my cats reaction to it, and there is absolutely nothing that I can put it into to hide it. I am just hoping that it does what it's supposed to do and I am thankful it's a very small amount. What would be nice would be to have a closed top that you would be able to get it out of instead of having to stick the syringe into it..


Rated 5 out of 5 stars
By Kris on Oct 29, 2022
Top 500 Contributor

Seems to do the trick

This was prescribed for a kitten who might have anxiety or dominance issues which resulted in the occasional and unexpected urination on our dog beds or sofa (other

This was prescribed for a kitten who might have anxiety or dominance issues which resulted in the occasional and unexpected urination on our dog beds or sofa (other medical/physical issues had been eliminated). We're nearly six weeks into this Prozac treatment and, so far, so good... The kitten obviously doesn't like the taste or the administration, but she's learned to deal with it. We opted against a flavored version due to the negative reviews.


Rated 4 out of 5 stars
By Fran on Jun 12, 2025

The medication does what it is prescribed for

We think it works for his medical issue he doesn't like it because of the taste

We think it works for his medical issue he doesn't like it because of the taste