Credelio Quattro Chewable Tablets for Dogs, 50.1-100 lbs, 1 Chewable (1-mo. supply)

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Medications ship separately. Delivery times may vary.

About This Item

Details

  • Credelio Quattro: The broadest1 parasite protection of its kind covering 6 types of parasites, including ticks, in one chewable tablet.
  • This monthly flea and tick treatment also protects against heartworm disease and three intestinal worms that can be passed to humans – roundworms, hookworms† and tapeworms † Uncinaria stenocephala
  • Easy-to-Give Chewable: This FDA-approved parasite protection comes in a flavored chewable tablet that is given once a month with food or within 30 minutes of a meal.
  • Prescription Only: Credelio Quattro is a prescription medication for puppies and dogs at least 8 weeks old and weighing at least 3.3 lbs.
  • 1Based on label comparison of the number of parasite types covered in an isoxazoline endectocide.

Ingredients

Instructions

FAQ

Get 6-in-1 Parasite Protection

Introducing Credelio Quattro (lotilaner, moxidectin, praziquantel, and pyrantel chewable tablets) for dogs, a prescription medication that protects your dog from common parasites. Unlike other chewables, Credellio Quattro protects against 6 types of parasites, including ticks, fleas, heartworm disease and three intestinal worms that can be passed to humans – 3 species of tapeworms, roundworms and hookworms.

Protection in a Tasty Chewable

Credelio Quattro combines convenience with flavor. A beef-flavored, once-monthly tablet that makes it easy to administer. Enjoy peace of mind knowing your dog’s protection is effective and easy to give.

The Power of Four

Credelio Quattro features four tried and true active ingredients designed to combat parasites effectively. With lotilaner, moxidectin, pyrantel and praziquantel, this advanced formula provides your pet with the broadest parasite protection of its kind based on label comparison of the number of parasite types covered.

Shown To Be Safe for Dogs and Puppies

Use Credelio Quattro to help protect your dog proactively before problems happen. This preventive treatment is shown to be safe for puppies as young as 8 weeks old and weighing at least 3.3 lbs.

About Credelio Quattro

Prescription only. Ask your veterinarian if Credelio Quattro is right for your dog.

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Indications

Credelio Quattro is indicated for the prevention of heartworm disease and the treatment and control of roundworm, hookworm, and tapeworm infections. Credelio Quattro kills adult fleas and is indicated for the treatment and prevention of flea infestations and the treatment and control of tick infestations for 1 month in dogs and puppies 8 weeks of age and older and weighing 3.3 pounds or greater.

Important Safety Information

Lotilaner, an ingredient in Credelio Quattro, belongs to the isoxazoline class and has been associated with neurologic adverse reactions like tremors, ataxia, and seizures even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders. Dogs should be tested for existing heartworm infections before Credelio Quattro administration as it is not effective against adult D. immitis. The safe use in breeding, pregnant, or lactating dogs has not been evaluated. The most frequently reported adverse reactions in clinical trials were vomiting and diarrhea. For complete safety information, please see the Credelio Quattro product label or ask your veterinarian.

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Reviews
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4.6
Rated 4.6 out of 5 stars
427 Ratings
Terms & Conditions

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

85% Positive

Effectiveness

84% Positive

Ingredients

83% Positive

Long-Term Benefits

84% Positive

141 Customer Reviews

Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 4 out of 5 stars
By Carolyn on Feb 24, 2026

CREDELIO QUATTRO chewable tablets

I LOVE that this one monthly product prevents heartworm, treats and controls multiple varieties of roundworms, hookworm, and tapeworms. It kills adult fleas and

I LOVE that this one monthly product prevents heartworm, treats and controls multiple varieties of roundworms, hookworm, and tapeworms. It kills adult fleas and prevents future flea infestations. It also treats and prevents infestations of four types of dog ticks! WOW! It is a monthly tablet for all of those yucky bugs. I used to have to give all my dogs separate monthly medications including the very sticky liquid on their necks (you probably know what I’m talking about.) It is expensive BUT, if you add up all the products you’d need instead, it’s cost effective. Plus it’s only one thing to put on your calendar! I will say that the tablet for the 50-100 pound dogs is large. One of my dogs needs it covered in peanut butter first. Haha

Rated 1 out of 5 stars
By joy on Mar 25, 2026

It never was delivered

Chewy is very hard to deal with. They have a really bad delivery service called on track and you don’t get your medicine. If you call about it you will be working

Chewy is very hard to deal with. They have a really bad delivery service called on track and you don’t get your medicine. If you call about it you will be working on it for three days and still don’t get it resolved. Very bad service.

Rated 5 out of 5 stars
By Shelley on Feb 9, 2026

CREDELIO & CHEWY, ARE THE BEST !

CREDILEO QUATTRO IS THE ABSOLUTE BEST ALL TIME COVERAGE YOU CAN BUY FOR YOUR DOG IT COVERS ALL THE WORMS TYPES AND BEST PART IS IT ALSO COVERS THE HEART SO ONE

CREDILEO QUATTRO IS THE ABSOLUTE BEST ALL TIME COVERAGE YOU CAN BUY FOR YOUR DOG IT COVERS ALL THE WORMS TYPES AND BEST PART IS IT ALSO COVERS THE HEART SO ONE PILL ONCE A MONTH FOR EVERYTHING AND CHARLIE JEAN IS PROTECTED FROM EVERYTHING,THATS WHAT I LIKE. ONE AND DONE YES ,CHARLIE AND I HIGHLY RECOMMEND IT PLUS CHEWY DOES ALL THE HARD WORK AND GETS YOUR PRESCRIPTION FILLED AND SENT TO YOU WHAT MORE COULD WE NEED ? ITS PERFECT THANK YOU, CHEWY

Rated 1 out of 5 stars
By Patricia on Jan 3, 2026

poor delivery

Dogs do well on the prescription. However: Rcvd notification package was delivered. Camera did not show arrival. Checked at door in case camera malfunctioned

Dogs do well on the prescription. However: Rcvd notification package was delivered. Camera did not show arrival. Checked at door in case camera malfunctioned. Nope, no package. When checking website re: delivery; stated that pkg was left at front door. Walking dogs next morning, found package had been left on top of mailbox. Over $400.00 in dog meds left on the top of the mailbox on a dirt road at a rural address with properties more than an acre apart. Called Chewy to state dissatisfaction. C/S apologized. I'll find another supplier.

Rated 1 out of 5 stars
By Richard on Mar 7, 2026

Our dog won't eat it.

We hav a standard poodle that will eat anything. We don't know of anything he has refused to eat except this. It's impossible to mask whatever it is he doesn't

We hav a standard poodle that will eat anything. We don't know of anything he has refused to eat except this. It's impossible to mask whatever it is he doesn't like. I purchased a six pack and used two. Can I return the other four?

Rated 5 out of 5 stars
By Lorraine on Mar 11, 2026

promptness

The product seems to work we have alot of deer and bunnies so I need to be sure she is covered as far as worms and ticks and fleas. She tends to eat anything on

The product seems to work we have alot of deer and bunnies so I need to be sure she is covered as far as worms and ticks and fleas. She tends to eat anything on the ground so this allows me some peace of mind.

Rated 5 out of 5 stars
By Carol on Mar 31, 2026

REDELIO QUATTRO Chewable Tablets came vet recommended

REDELIO QUATTRO Chewable Tablets - Our Lab takes this easily. We live in a tick infested area, and I am so grateful that this seems to be doing the trick.

REDELIO QUATTRO Chewable Tablets - Our Lab takes this easily. We live in a tick infested area, and I am so grateful that this seems to be doing the trick.

Rated 4 out of 5 stars
By Oliver on Jan 16, 2026

huge pill & very pricy - but it works!

this medication does a great job (we have not seen ANY fleas or ticks on our dog since starting it) BUT the pills are absolutely huge, like comically large. this

this medication does a great job (we have not seen ANY fleas or ticks on our dog since starting it) BUT the pills are absolutely huge, like comically large. this will be a real challenge if your dog has a hard time with pills. Chewy has by far the best price for this item especially with the chewy plus and autoship, but it is still very pricy, would be great to see this on sale more often, or see the price lowered.

Rated 2 out of 5 stars
By Christina on Mar 15, 2026

Hard to Swallow

My dog hates this medication. It takes numerous tries and doctoring up concoctions to get him to take this medicine. I will be trying something different next t

My dog hates this medication. It takes numerous tries and doctoring up concoctions to get him to take this medicine. I will be trying something different next time.

Rated 5 out of 5 stars
By Michelle on Mar 11, 2026

Flea Drops

My Echo was feeling it with the fleas before the meds. The weather was changing, so they were out a little early. The meds did the trick!! Thank you!!

My Echo was feeling it with the fleas before the meds. The weather was changing, so they were out a little early. The meds did the trick!! Thank you!!