Credelio Quattro Chewable Tablets for Dogs, 12.1-25 lbs, 1 Chewable (1-mo. supply)

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About This Item

Details

  • Credelio Quattro: The broadest1 parasite protection of its kind covering 6 types of parasites, including ticks, in one chewable tablet.
  • This monthly flea and tick treatment also protects against heartworm disease and three intestinal worms that can be passed to humans – roundworms, hookworms† and tapeworms † Uncinaria stenocephala
  • Easy-to-Give Chewable: This FDA-approved parasite protection comes in a flavored chewable tablet that is given once a month with food or within 30 minutes of a meal.
  • Prescription Only: Credelio Quattro is a prescription medication for puppies and dogs at least 8 weeks old and weighing at least 3.3 lbs.
  • 1Based on label comparison of the number of parasite types covered in an isoxazoline endectocide.

Ingredients

Instructions

FAQ

Get 6-in-1 Parasite Protection

Introducing Credelio Quattro (lotilaner, moxidectin, praziquantel, and pyrantel chewable tablets) for dogs, a prescription medication that protects your dog from common parasites. Unlike other chewables, Credellio Quattro protects against 6 types of parasites, including ticks, fleas, heartworm disease and three intestinal worms that can be passed to humans – 3 species of tapeworms, roundworms and hookworms.

Protection in a Tasty Chewable

Credelio Quattro combines convenience with flavor. A beef-flavored, once-monthly tablet that makes it easy to administer. Enjoy peace of mind knowing your dog’s protection is effective and easy to give.

The Power of Four

Credelio Quattro features four tried and true active ingredients designed to combat parasites effectively. With lotilaner, moxidectin, pyrantel and praziquantel, this advanced formula provides your pet with the broadest parasite protection of its kind based on label comparison of the number of parasite types covered.

Shown To Be Safe for Dogs and Puppies

Use Credelio Quattro to help protect your dog proactively before problems happen. This preventive treatment is shown to be safe for puppies as young as 8 weeks old and weighing at least 3.3 lbs.

About Credelio Quattro

Prescription only. Ask your veterinarian if Credelio Quattro is right for your dog.

Shop Credelio

Indications

Credelio Quattro is indicated for the prevention of heartworm disease and the treatment and control of roundworm, hookworm, and tapeworm infections. Credelio Quattro kills adult fleas and is indicated for the treatment and prevention of flea infestations and the treatment and control of tick infestations for 1 month in dogs and puppies 8 weeks of age and older and weighing 3.3 pounds or greater.

Important Safety Information

Lotilaner, an ingredient in Credelio Quattro, belongs to the isoxazoline class and has been associated with neurologic adverse reactions like tremors, ataxia, and seizures even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders. Dogs should be tested for existing heartworm infections before Credelio Quattro administration as it is not effective against adult D. immitis. The safe use in breeding, pregnant, or lactating dogs has not been evaluated. The most frequently reported adverse reactions in clinical trials were vomiting and diarrhea. For complete safety information, please see the Credelio Quattro product label or ask your veterinarian.

4.6
Rated 4.6 out of 5 stars
317 Ratings

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

83% Positive

Effectiveness

81% Positive

Ingredients

81% Positive

Long-Term Benefits

80% Positive

113 Customer Reviews



Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 3 out of 5 stars
By Sheila on Feb 23, 2026

Perfect All in One

My vet recommended this for my Shih Tzu for a couple reasons. First, we winter travel and will be in Alabama, Florida, Tennessee for 2 months and because heartworm

My vet recommended this for my Shih Tzu for a couple reasons. First, we winter travel and will be in Alabama, Florida, Tennessee for 2 months and because heartworm is common in these states she wanted Poika protected. Also, because it's an all in one I don't have to give multiple pills. Poika has not done well with any other chewable pills, they always make him sick. He's had one dose of this, will do it the 1st of every month. So far, he did good and didn't get sick. Picture is of my Poika. (means boy in Finnish)


Rated 4 out of 5 stars
By Nicki on Mar 30, 2026

Fast Shipping

Great med! The only difficulty is I was unable to scan the prescription in and submit myself as you can with other prescriptions. It had to come directly from my

Great med! The only difficulty is I was unable to scan the prescription in and submit myself as you can with other prescriptions. It had to come directly from my vet, which caused a bit of a holdup. Otherwise, great experience!


Rated 1 out of 5 stars
By Diana on Jan 20, 2026

Delivery was terrible

I have ordered medication 2x and both deliveries were left at the street by (not inside) the mailbox. After the first mis delivery I called Chewy. They amended

I have ordered medication 2x and both deliveries were left at the street by (not inside) the mailbox. After the first mis delivery I called Chewy. They amended delivery instructions to go down the driveway to see the house. They still left it at the street. Medications are far to necessary and expensive for this to keep happening. The Actual Chewy drivers who deliver cat food and litter carry it to my door. You need to get a different delivery service for your medications. I will no longer use Chewy for my pets meds.


Rated 5 out of 5 stars
By Norma on Mar 28, 2026

Quick delivery.

This preventative maintenance works for my furry Neena doggie, and it covers and protects her from all the outside ticks and more throughout the year.

This preventative maintenance works for my furry Neena doggie, and it covers and protects her from all the outside ticks and more throughout the year.


Rated 5 out of 5 stars
By Susan on Mar 21, 2026

Great combo in a chewable!

I didn’t like the topical meds for my dog, and having schedule two different ones was a hassle. This chewable solves both problems!

I didn’t like the topical meds for my dog, and having schedule two different ones was a hassle. This chewable solves both problems!


Rated 5 out of 5 stars
By Deborah on Mar 31, 2026

Love it

I really am so happy that my vet told me about this product. It works well for my dog.

I really am so happy that my vet told me about this product. It works well for my dog.


Rated 5 out of 5 stars
By Dan on Apr 1, 2026

One step

Easy to have one dose cover multiple issues. Our vet endorsed our decisions

Easy to have one dose cover multiple issues. Our vet endorsed our decisions


Rated 5 out of 5 stars
By Veronica on Mar 21, 2026

Quick and easy!

Easy ordering, quick approval from my vet clinic and delivered very fast.

Easy ordering, quick approval from my vet clinic and delivered very fast.


Rated 3 out of 5 stars
By Tin on Mar 26, 2026

gave him diarrhea

we did not enjoy the side effects but it was recommended by his vet

we did not enjoy the side effects but it was recommended by his vet


Rated 5 out of 5 stars
By brenda on Mar 18, 2026

She didn't fight when giving her the medicine.

She's really a picky girl, but she had no problem with this pill.

She's really a picky girl, but she had no problem with this pill.