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Credelio Chewable Tablet for Dogs, 25.1-50 lbs, (Green Box), 3 Chewable Tablets (3-mos. supply)

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About This Item

Details

  • Tick and flea treatment & infestation prevention for dogs 25.1 to 50.0 lbs., at least 8 weeks of age
  • Fast-acting ingredients start killing Ixodes ricinus ticks & adult fleas in just 4 hours
  • Kills 100% of fleas in 12 hours & stays effective throughout the entire month
  • Easy to give your dog; no greasy, messy application
  • Small, beef-flavored chewable tablet accepted by 100% of dogs tested (Karadzovska D, Chappell K, Coble S, et al. A randomized, controlled field study to assess the efficacy and safety of lotilaner flavored chewable tablets (Credelio) in eliminating fleas in client-owned dogs in the USA. Parasite Vector. 2017;10(1):528.)
  • The U.S. Food and Drug Administration has issued an Emergency Use Authorization (EUA) for the treatment of New World screwworm (NWS) infestations (myiasis). The FDA has concluded that based on the totality of the scientific evidence available, this drug may be effective in the treatment of NWS myiasis, and the known and potential benefits of the product outweigh its known and potential risks.

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4.7
Rated 4.7 out of 5 stars
1124 Ratings
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Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

88% Positive

Effectiveness

88% Positive

Ingredients

84% Positive

Long-Term Benefits

86% Positive

304 Customer Reviews

Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 5 out of 5 stars
Verified Purchase
By YesIamthatdogmom on Sep 26, 2025

My MDR1+ Aussie has no issue

I have an Aussie and had been giving her credilio for years now. Not only does it work incredibly as I’ve seen the dead ticks and one running for their lives but

I have an Aussie and had been giving her credilio for years now. Not only does it work incredibly as I’ve seen the dead ticks and one running for their lives but recently found out after a failed attempt at a dental cleaning, she is MDR1+. She has never had an issue with this medication. Phew!! I recently gave her a little brother and when the vet suggested the same preventative, I felt very comfortable saying yes!!

Rated 5 out of 5 stars
By Heretique on May 28, 2019

Apartment nightmares

When you are in an apartment, things spread especially with shared dog yards. After about 8 months, i suddenly became infested. I fought with it for over 2 years

When you are in an apartment, things spread especially with shared dog yards. After about 8 months, i suddenly became infested. I fought with it for over 2 years. By infested i mean, all over them, me, etc. My white dog had a lot of black moving spots. INFESTED. I would literally have panic attacks and cry. I had to tell friends they could not visit. I had to hear my dogs whimper. It was awful and i would breakdown feeling like the worse piece of trash for not being able to get rid of them. I tried 8 different brands of both oral and topical treatments. Bombed the house. Destroyed a dyson using d.e. on the carpets, used carpet sprays.... tried so much. I was at my wits end. Then came this. Within 1 day, a HUGE difference one my dogs. I was visiting my mom. Went home and within days, the majority were gone. After a few weeks and the preexisting eggs hatched, they died quickly. It has been a year and they have a customer for life. Meds dont work for every animal out there, but for my dogs (and my sanity), this has been a huge blessing i cannot and will not live with.

Rated 5 out of 5 stars
Verified Purchase
By Michelle on Jul 21, 2025

Kills ALL the ticks

My puppy is a collie with the MDR1 mutation, so he can’t take the more popular tick preventatives. I did a ton of research to find the best product that was safe

My puppy is a collie with the MDR1 mutation, so he can’t take the more popular tick preventatives. I did a ton of research to find the best product that was safe for him, and Credelio is the bomb! Did you know that most tick preventatives only kill one or two types of ticks? I didn’t either! No wonder some of them didn’t work on our previous dog after we moved! Well Credelio kills four kinds of ticks, AND it’s safe for dogs with MDR1. Win win! My pup has been on it for a month now and every tick I’ve found on him that wasn’t right after we came inside was DEAD. That’s what I like in a tick preventative! Awesome product!

Rated 5 out of 5 stars
Verified Purchase
By Delores on Feb 14, 2024

Pricey but she eats it

I had been using Frontline Plus for years then suddenly about 3 months ago she refused to let me put it on her. If she saw me going to the cabinet where it was she

I had been using Frontline Plus for years then suddenly about 3 months ago she refused to let me put it on her. If she saw me going to the cabinet where it was she ran away and hid, After talking to my vet we decided to try Credelio, at least she will eat that. It’s expensive but so was my do. luckily it is a bit cheaper at Chewy!

Rated 3 out of 5 stars
Verified Purchase
By Denise on Jan 10, 2025

Neurological Issues

Since being on Credelio, both of my dogs have demonstrated different level of neurological issues. One has Lar Par (14 years old) the other dog has shaky legs at

Since being on Credelio, both of my dogs have demonstrated different level of neurological issues. One has Lar Par (14 years old) the other dog has shaky legs at 8 years old-and she's only a medium size dog-so she's got years left. Not sure if Credelio is to blame, but it makes sense given the warnings about it in this regard. So, rating of 3 because it does work very well. Knocking two stars off due to my insecurity in using the product.

Rated 5 out of 5 stars
Verified Purchase
By Happy on Aug 1, 2021

Finally something has worked for fleas

Since Frontline and Advantix, all types, quit working for our dogs we have tried everything. The only thing we found that would kill the fleas was Dawn...but how

Since Frontline and Advantix, all types, quit working for our dogs we have tried everything. The only thing we found that would kill the fleas was Dawn...but how many times can you wash your dogs? We vacuum daily..even the dogs. Nothing worked. Then Credelio arrived Friday, yesterday and we added it to their dinner. All 7 dogs are laying here quietly not scratching. I flea combed them and NOTHING! I almost cried I was so happy. This worked..and fast. Let's just hope it keeps working and the fleas don't build up a resistance. Thank you Credelio.

Rated 5 out of 5 stars
Verified Purchase
By Christy on Jan 14, 2024

Works

I adopted a dog in May who had been prescribed this specific flea/tick medication because when he came to the rescue he had a bit of demodex and this cleared it

I adopted a dog in May who had been prescribed this specific flea/tick medication because when he came to the rescue he had a bit of demodex and this cleared it up. Fastforward to recently and the puppy we took in shortly after recently had some spots show up on her skin that appeared to either be yeast or possibly some demodex. After cleaning the spots on her skin with medicated wipes for a few weeks, I ordered this for both doggos again and her skin has cleared right up. I generally don't treat for fleas during the winter as it's usually not an issue, but this is what we will be using going forward due to its efficacy for fleas, ticks, and mites at the price point. Also, no weird side effects or behaviors in either dogs.

Rated 3 out of 5 stars
By AdultMaleCavachon on Mar 26, 2022

It works, if they take it.

The protection is excellent. I've had to skip months and still some see dead fleas who tried and failed to setup camp on my boy, long after he's do for a re-dose

The protection is excellent. I've had to skip months and still some see dead fleas who tried and failed to setup camp on my boy, long after he's do for a re-dose. But that is the problem. Besides being expensive, these are hard tablets like overbaked Flintstones vitamins. My dog will gobble up a real chewable, like his interceptor, but it's always a struggle to get him to take Credelio tablets. He's really not a picky eater. At all. Some dogs are obviously fine with this, but I've lost expensive pills to crumbles and goo piles trying everything from a food dish covered in gravy to the mighty Kraft singles trick. It's very frustrating. But that's just something to keep in mind before you buy in bulk. And maybe have a conversation with your Vet about alternatives if you also have this problem. But if your dog eats it, it's probably the best way to go.

Rated 5 out of 5 stars
Verified Purchase
By Kathleen on Oct 5, 2025

Love the oral flea/tick medicine and Chewy makes it easy.

Just started giving Credelio to my dog this year. So easy to just dose him once a month with an easy to feed pill. No mess, like the topicals and no potential skin

Just started giving Credelio to my dog this year. So easy to just dose him once a month with an easy to feed pill. No mess, like the topicals and no potential skin issues. Plus, I don't have to worry about touching him after dosing--don't have to wait for anything to dry. We started using this on my Mom's 10 yr. old dog instead of topicals when she had seborrhea on her back and we didn't want to use a topical. She did so well with it, that we both switched to Credelio permanently. I now use it on my puppy, too. Chewy makes ordering easy and they will contact your vet to make the process seamless!

Rated 5 out of 5 stars
Verified Purchase
By Rachael on Dec 4, 2024

Best Product

I have farm dogs in the mountains. Ticks are awful. This product kills them for at least 3 months. It only claims to work for one month. I gave them a dose in July

I have farm dogs in the mountains. Ticks are awful. This product kills them for at least 3 months. It only claims to work for one month. I gave them a dose in July. It’s now December and still working. I find dead dried up little ticks on my dogs. As soon as I realize the ticks aren’t dying I’ll order more. 100% worth the cost. Cause I was hand picking ticks off and it’s nasty. And if Chewy will contact the vet for a prescription and ship it to me, it’s a win for me cause I hate going to the vet office.