Comfort Zone Multi-Cat Calming Pheromone Diffuser Refill for Cats, 30-day, 6 count

Skip image gallery
Slide 1 of 13

At a Glance

  • Calming
  • All Lifestages

$36.72 First Time Autoship Price
this order
Save 35% (up to $20) today when you set up Autoship. 
$50.85 Autoship Price
(-10%) future orders
  • Keep saving 10% on every order
  • Get deliveries on your schedule
  • Skip, change, or cancel anytime
$56.50 Chewy Price
($9.42 /ea)
Save $3.49 (-6%)
$59.99 List Price
Promo, New Customers Only: Spend $49+, Get $20 eGift Card + Free Shipping with code: WELCOME
In Stock
FREE 1-3 day delivery
Free 365-day returns

No interest if paid in full in 6 months on PayPal purchases of $149+. .

About This Item

Details

  • These refills are compatible with Comfort Zone diffusers (sold separately) and the diffuser is reusable for up to 12 months when you replace the refill monthly.
  • Use to help reduce multiple cat household tension and aggressive behaviors like swatting, scratching, biting, fighting, hissing, growling, spitting, screaming, non-playful staring, stalking, chasing, and blocking.
  • This is a drug- and fragrance-free solution so you can feel good about helping your cat feel good.
  • This product meets strict electrical safety standards.
  • Comfort Zone has provided care with cat calming pheromones for over 20 years, making it a trusted choice for pet parents.

Ingredient Information

Instructions

Learn More About Comfort Zone From Our Team of Experts

About Comfort Zone Cat Calming Multi-Cat Diffuser

Curb Stress in Your Cat

Just like people, cats behave differently when stressed. Comfort Zone products help relax your cat to curb stress-related, disruptive behavior so your cat can feel and behave her best.

24/7 Behavioral Support

Place one Comfort Zone Calming Diffuser in each of your cat’s favorite rooms for a happier, calmer cat.

For Cool, Calm and Collected Cats

The drug-free mist in the Comfort Zone Multi-Cat Calming Diffuser helps promote positive behavior and harmony between cats. Use it to help reduce tension, conflict and disruptive behaviors and foster a more peaceful environment in multi-cat homes.

How it Works

The Comfort Zone calming mist dispensed by the diffuser contains pheromones that mimic a cat’s natural feline facial pheromones (FFP). These are the same pheromones your cat would leave behind when head bunting you or rubbing her face on the furniture, and they signal to cats that a place or object is safe and familiar. So, using the diffuser is like one big kitty face rub spread across the entire room!

How to Use

Always use the diffuser properly and with the vents facing up. Leave four feet of space around the diffuser and avoid plugging it under shelves, behind furniture or near vents and windows for best results. Replace the refill approximately every 30 days or earlier if you notice it is empty.

Vet Recommended

Provides behavioral support for cats 10 months and older when used as directed.

Improved Behavior

The diffuser helps reduce stress and promote positive behaviors, with noticeable improvement in as little as two weeks.

Pheromone Technology

Comfort Zone makes a full line of pheromone products to help your cat feel better.

Promotes Relaxation

The calming mist signals a feeling of safety to cats, lowering stress levels and promoting relaxation.

About Comfort Zone

Comfort Zone is dedicated to helping cats feel safe, calm and happy using signals they naturally understand. They make a wide range of products designed to promote positive behaviors and lower stress in cats. Their drug-free calming solutions can be used in and around the home or on the go. Take Comfort Zone anywhere your kitty needs to feel relaxed, safe and stress-free!

Shop Comfort Zone

Frequently bought together

Questions & Answers

19 Customer Questions

Will it still be effective in a room with an air purifier?

I have a multi-blend house. Is it safe for dogs?

Can you also use these diffusers relills in the feliway multi-cat defuser plugin will they also fit or so I have to buy ur starter kit for muliticat?

Answer by Chewy • Oct 11, 2019
Comfort Zone New Formula Calming Cat Diffuser Refill is not compatible with Feliway.

I see this product says “New Formula”... how does this product differ from the original Multi-Cat Calming diffusers?

Answer by Chewy • Jul 12, 2019
This formula contains two times the calming pheromones when compared to some other diffusers on the market.
Reviews
Write a Review
4.5
Rated 4.5 out of 5 stars
1590 Ratings
Terms & Conditions

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Coverage Area

83% Positive

Duration

82% Positive

Ease of Use

85% Positive

Effectiveness

84% Positive

612 Customer Reviews

Rated 5 out of 5 stars
By Ramona on Mar 20, 2026

It definitely calms him down!

We actually see him go over and sniff the diffuser on occasion! It does help him calm down and not be so aggressive towards his brother who has a handicap and requires

We actually see him go over and sniff the diffuser on occasion! It does help him calm down and not be so aggressive towards his brother who has a handicap and requires a little more attention. He will get jealous so this does help, although we try to equal our quality time with both cats. This helps at night time. We know when the diffusers are low because he starts acting up!

Rated 5 out of 5 stars
By Fay on Feb 1, 2026

Used Previously with Good Results

Bringing in a new furkid to join the crew is always stressful for everyone, especially when dealing with ferals. I've used this product in the past with good results

Bringing in a new furkid to join the crew is always stressful for everyone, especially when dealing with ferals. I've used this product in the past with good results when I adopted feral brother & sister kittens. We recently invited Stormy, a spayed female feral to join our family. These diffuser pheromones have helped keep things calm, and now he cats are play mates.

Rated 5 out of 5 stars
By Debbie on Mar 19, 2026

Great product for multi cat houses

I've used this for years. They have no scent for humans. I have 4 cats. I can tell when one of the dispensers is out because I start having cat fights. I have 3

I've used this for years. They have no scent for humans. I have 4 cats. I can tell when one of the dispensers is out because I start having cat fights. I have 3 going in my house at all times.

Rated 4 out of 5 stars
By Ronald on Mar 17, 2026

Calming Cats

I think it really helped calm my cats down. They were becoming very hostile in their playing with each other. The diffuser helped them and they are less hostile

I think it really helped calm my cats down. They were becoming very hostile in their playing with each other. The diffuser helped them and they are less hostile.

Rated 1 out of 5 stars
By Deb on Mar 29, 2026

This looks just like Feliway and it is NOT

My cats did not tolerate this and I’d bought it by mistake because the packaging is so similar. Do not be fooled. This is NOT Feliway.

My cats did not tolerate this and I’d bought it by mistake because the packaging is so similar. Do not be fooled. This is NOT Feliway.

Rated 1 out of 5 stars
By Katherine on Dec 31, 2025

Didn't work at all. I have been using 5 different pheromone diffusers

I have been using 5 different pheromone diffusers for 6 months. I have one plugged in each room, including the small laundry room. Aggressive attacks from Spotzie

I have been using 5 different pheromone diffusers for 6 months. I have one plugged in each room, including the small laundry room. Aggressive attacks from Spotzie onto Delilah happened every day that me or my husband did not supervise 100% with a squirt gun, so we have been squirting Spotzie a lot with water. It is true that punishment only works as long as the punisher is present.

Rated 4 out of 5 stars
By Margaret on Mar 8, 2026

Twelve cats and no real fights.

With twelve cats there are bound to be occasional spats. I adjust the density of the diffusers to the needs of the various cats. Mostly it seems to work.

With twelve cats there are bound to be occasional spats. I adjust the density of the diffusers to the needs of the various cats. Mostly it seems to work.

Rated 5 out of 5 stars
By Luz on Feb 9, 2026

Unexpected cat neighborhood visit

A friendly cat followed my cat and my cat was not happy, I connected the diffuser and my cat calmed down and the neighbor’s cat stayed a little while sniffing the

A friendly cat followed my cat and my cat was not happy, I connected the diffuser and my cat calmed down and the neighbor’s cat stayed a little while sniffing the area, rested and then left.

Rated 5 out of 5 stars
By Erin on Nov 24, 2025

Helps with anxiety

I have a cat with severe anxiety (she's a Napoleon cat). She takes Prozac and it helps but has not fully resolved her issues. I have also added in a probiotic for

I have a cat with severe anxiety (she's a Napoleon cat). She takes Prozac and it helps but has not fully resolved her issues. I have also added in a probiotic for anxiety and these diffusers and have seen a dramatic improvement over time. She is now making friendly gestures towards my other cat and is not pulling out her fur as much as she was. Her anxiety is severe so she needs multiple treatments but this was added at a different time than the other treatments so I'm sure that it is responsible for part of her improvement.

Rated 5 out of 5 stars
By Kate on Feb 4, 2026

Dixie is new to me & my other 3cats

She wouldn’t eat the Tastefuls, either. This is the 2nd and last time I will purchase this food. I gave it to the local Humane Society, as all 4 cats will NOT eat

She wouldn’t eat the Tastefuls, either. This is the 2nd and last time I will purchase this food. I gave it to the local Humane Society, as all 4 cats will NOT eat it. Where’s the Gravy??