Comfort Zone Multi-Cat Calming Pheromone Diffuser Refill for Cats, 30-day, 6 count

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About This Item

Details

  • Compatible with Comfort Zone diffusers only (sold separately)—just replace the refill monthly for a continuous calming effect.
  • Comfort Zone has provided care with cat calming pheromones for over 20 years, making it a trusted choice for pet parents.
  • Helps create a calm environment that encourages positive behaviors, with most kitties showing results in one week
  • Drug- and fragrance-free solution so you can feel good about helping your furry friends feel good.
  • Refills provide the same pheromone power for great results you can count on.

Ingredient Information

Instructions

Learn More About Comfort Zone From Our Team of Experts

About Comfort Zone Cat Calming Multi-Cat Diffuser

Curb Stress in Your Cat

Just like people, cats behave differently when stressed. Comfort Zone products help relax your cat to curb stress-related, disruptive behavior so your cat can feel and behave her best.

24/7 Behavioral Support

Place one Comfort Zone Calming Diffuser in each of your cat’s favorite rooms for a happier, calmer cat.

For Cool, Calm and Collected Cats

The drug-free mist in the Comfort Zone Multi-Cat Calming Diffuser helps promote positive behavior and harmony between cats. Use it to help reduce tension, conflict and disruptive behaviors and foster a more peaceful environment in multi-cat homes.

How it Works

The Comfort Zone calming mist dispensed by the diffuser contains pheromones that mimic a cat’s natural feline facial pheromones (FFP). These are the same pheromones your cat would leave behind when head bunting you or rubbing her face on the furniture, and they signal to cats that a place or object is safe and familiar. So, using the diffuser is like one big kitty face rub spread across the entire room!

How to Use

Always use the diffuser properly and with the vents facing up. Leave four feet of space around the diffuser and avoid plugging it under shelves, behind furniture or near vents and windows for best results. Replace the refill approximately every 30 days or earlier if you notice it is empty.

Vet Recommended

Provides behavioral support for cats 10 months and older when used as directed.

Improved Behavior

The diffuser helps reduce stress and promote positive behaviors, with noticeable improvement in as little as two weeks.

Pheromone Technology

Comfort Zone makes a full line of pheromone products to help your cat feel better.

Promotes Relaxation

The calming mist signals a feeling of safety to cats, lowering stress levels and promoting relaxation.

About Comfort Zone

Comfort Zone is dedicated to helping cats feel safe, calm and happy using signals they naturally understand. They make a wide range of products designed to promote positive behaviors and lower stress in cats. Their drug-free calming solutions can be used in and around the home or on the go. Take Comfort Zone anywhere your kitty needs to feel relaxed, safe and stress-free!

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Questions & Answers

21 Customer Questions


Will it still be effective in a room with an air purifier?


I have a multi-blend house. Is it safe for dogs?


Can you also use these diffusers relills in the feliway multi-cat defuser plugin will they also fit or so I have to buy ur starter kit for muliticat?

Answer by ChewyOct 11, 2019
Comfort Zone New Formula Calming Cat Diffuser Refill is not compatible with Feliway.

I see this product says “New Formula”... how does this product differ from the original Multi-Cat Calming diffusers?

Answer by ChewyJul 12, 2019
This formula contains two times the calming pheromones when compared to some other diffusers on the market.

4.5
Rated 4.5 out of 5 stars
1655 Ratings

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Coverage Area

83% Positive

Duration

82% Positive

Ease of Use

85% Positive

Effectiveness

84% Positive

630 Customer Reviews



Rated 5 out of 5 stars
By Erin on Nov 24, 2025

Helps with anxiety

I have a cat with severe anxiety (she's a Napoleon cat). She takes Prozac and it helps but has not fully resolved her issues. I have also added in a probiotic for

I have a cat with severe anxiety (she's a Napoleon cat). She takes Prozac and it helps but has not fully resolved her issues. I have also added in a probiotic for anxiety and these diffusers and have seen a dramatic improvement over time. She is now making friendly gestures towards my other cat and is not pulling out her fur as much as she was. Her anxiety is severe so she needs multiple treatments but this was added at a different time than the other treatments so I'm sure that it is responsible for part of her improvement.

By Erin on Nov 24, 2025

Rated 1 out of 5 stars
By Joan on Jan 1, 2025

Product Should Be Banned

Vet recommended to buy Feliway. I ran across the Comfort Zone and for the price, I purchased. Bad decision on my part. I was told to plug it in where my 4 kids hung

Vet recommended to buy Feliway. I ran across the Comfort Zone and for the price, I purchased. Bad decision on my part. I was told to plug it in where my 4 kids hung out the most. Well, duh, kitchen. So I plugged it in at the island near their bowls on the floor. One morning after several weeks I noticed this large area on my granite countertop. At first I thought it was blood or urine from one of my cats. I panicked and checked on all 4 cats. Thankfully all were good. The next thing I immediately noticed was this plug in and the greasy oil substance on my cabinet and under the unsealed granite countertop. There you go, my brand new home kitchen's island is damaged beyond repair. We have had several contractors here trying to remove this substance to no avail. Now we've dealing with the company for a couple of months for authorization to move forward in replacing this countertop. I have read on other reviews that this product HAS CAUSED FIRES. this product should be taken off the market immediately! Trust me, trust these reviews, it never worked, 2 of my cats lost their meows, it ruined my granite countertop and wood cabinet. Consider yourself warned! I wish someone had warned me.

By Joan on Jan 1, 2025

Rated 5 out of 5 stars
By Michelle on Sep 12, 2020

Works fast even with stubborn cats

I've used the feliway classic in the past to help introduce a new kitten to older, stubborn cats but when I recently brought in a 6 month old rescue cat in desperate

I've used the feliway classic in the past to help introduce a new kitten to older, stubborn cats but when I recently brought in a 6 month old rescue cat in desperate need of food and a home my boys went full offensive on her. Because of the new cat's lack of socialization and semi feral upbringing (at 6 months old she had never been indoors until I brought her in) my indoor cats felt threatened and she was scared. Spent several days of slow introduction and allowing her to retreat outside when she became too stressed. I received these refills this morning and promptly put them in. The new cat came back inside for dinner and was accepted in the kitchen with no hissing or snarling. Previously she was always made to eat in the livingroom where the others could not see her to keep stress levels down. My big male even gave up his normal dinner dish to her tonight with no complaints. There has been no physical aggression with these defusers running. There has been less fleeing from each other this evening. The behavior of all 4 cats has changed drastically within the past 12 hours. There is still some grumbling and hissing but they are noticeably less stressed even when in close proximity to each other. These are very helpful to create a calm, inviting environment and I plan to keep these running in the main rooms the cats occupy while they acclimate and while their new friend learns the rules of the house.

By Michelle on Sep 12, 2020

Rated 5 out of 5 stars
By HopperPups on Oct 28, 2024

Love is in the Air. No Wait, itsComfortZone

We bought these to make the move to our new home less stressful. We kept up with changing the refills until they seemed more settled in and because we had our firstborn

We bought these to make the move to our new home less stressful. We kept up with changing the refills until they seemed more settled in and because we had our firstborn a few months ago. These past few days the cats have been literally running off the walls and even fighting. At 12am we realized the plugs were out so we replaced them and not even 24 hours later they are back to loving on each other. Needless to say we LOVE this product!

By HopperPups on Oct 28, 2024

Rated 5 out of 5 stars
By EmmaMarie on Oct 14, 2025

Comfort Zone made my Zone Comfortable.

I have 8 cats. 1 spayed female and 4 nutered males, all litter mates and in the house. Bedtime was a nightmare with all 5 running, jumping on the kitchen counters,

I have 8 cats. 1 spayed female and 4 nutered males, all litter mates and in the house. Bedtime was a nightmare with all 5 running, jumping on the kitchen counters, climbing in my pantry, running and sliding off of furniture, scratching furniture, and worst of all...climbing my curtains. They had me climbing the walls! I had tried sprays to keep them off of the furniture - which DID NOT work. So finally after reading reviews of Pheromone products for cats, I decided on trying Comfort Zone. It has been a blessing in a little bottle. No more running through the house like maniacs, no more climbing curtains, climbing on kitchen counters or in the pantry. They still have their playtime but it is sooo much more calm now. I was very pleasantly surprised at how wonderful this product is. I am sure that it does not work for everyone but so for me, it is a God Send (a Chewy Send).

By EmmaMarie on Oct 14, 2025

Rated 5 out of 5 stars
By Christine on Oct 30, 2025

Peace in a Diffuser

I love these diffusers so much and buy them on repeat. Ever since the Cat distribution system added a kitten to our home 2 years ago, there has been mild chaos in

I love these diffusers so much and buy them on repeat. Ever since the Cat distribution system added a kitten to our home 2 years ago, there has been mild chaos in the home between cats even with proper introductions. These plug-ins have been a game changer. There is peace once again! Of course there are still small disagreements but nothing like the yelling & tuffs of hair incidents of the past. These work so well, I have been using them for almost a year and I can seriously tell when the diffusers run low when the confrontations start up again. Highly recommend these for multiple cat households but you need to commit and add them in all common rooms and keep them filled.

By Christine on Oct 30, 2025

Rated 5 out of 5 stars
By Jennifer on Jun 6, 2025

Calming the stinker Bum kitties

They all do it, a little tease here and a little tease there, until one is hissing and wants to get away. Comfort Zone brings play time back, with naps and snuggles

They all do it, a little tease here and a little tease there, until one is hissing and wants to get away. Comfort Zone brings play time back, with naps and snuggles after chasing the colorful balls and mice.

By Jennifer on Jun 6, 2025
Cinder
Cinder

Rated 5 out of 5 stars
By Jenn on May 26, 2025

Comparable to Feliway

We've tried Comfort Zone and Feliway to help our cattos feel a sense of calm, around the house. We ultimately ended up with Comfort Zone because of the price of

We've tried Comfort Zone and Feliway to help our cattos feel a sense of calm, around the house. We ultimately ended up with Comfort Zone because of the price of the refills. I feel like "Feliway Diffuser" is almost synonymous with "pheromone diffuser for cats," much like folks ask for a Kleenex or a Coke. In our experience, Comfort Zone's product is comparable to Feliway's. Note: This product is REFILLS ONLY. You will already need to own a Comfort Zone diffuser to use these refills. Chewy sells the diffusers, too, so have a browse.

By Jenn on May 26, 2025

Rated 1 out of 5 stars
By Amanda on Sep 8, 2025
Top 250 Contributor

These don't work!

I have a multiple cat household so there is always somebody hissing, growling, hitting, chasing, etc. I purchased these in hopes of calming everybody down and helping

I have a multiple cat household so there is always somebody hissing, growling, hitting, chasing, etc. I purchased these in hopes of calming everybody down and helping them tolerate each other a little bit. I have a 2 story house and have all 6 of these diffusers in use. None are by a window, register vent or obstructed by furniture. Since I have been using these diffusers, the fighting has actually gotten worse. Somebody is constantly growling and hitting somebody else. I wake up in the middle of the night to cats screaming because they are being attacked by other cats. These diffusers may work for some but not for us. They have made our situation so much worse. I wish I hadn't wasted so much money on these.

By Amanda on Sep 8, 2025
Top 250 Contributor

Rated 5 out of 5 stars
By LaCoqueta on Nov 13, 2019

Now a believer!

Despite my skepticism, I tried this on my vets recommendation for my cats predatory behaviors with my bare feet and friends’ hands. I noticed a difference after

Despite my skepticism, I tried this on my vets recommendation for my cats predatory behaviors with my bare feet and friends’ hands. I noticed a difference after about two weeks. I can tell when I need to change the cartridge by my cats behavior. He has become the affectionate kitty that was always there but obfuscated by anxiety, and without having to resort to Prozac or keflar protective gear when going to pet him!

By LaCoqueta on Nov 13, 2019