Amitriptyline HCl (Generic) Tablets, 10-mg, 30 tablets

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About This Item

Details

  • Treats behavior conditions, pruritus, postspaying urinary incontinence, chronic pain in dogs and anxiety, behavior conditions, and as adjunctive treatment of neuropathic pain in cats.
  • Works by blocking the reabsorptin of serotonin and norepinephrine. By increasing the amount of both of these, Amitriptyline helps the brain regulate mood and behavior.
  • Not given on an as needed basis, but continously and may require several weeks to see a positive response.
  • Contact your veterinarian before making any treatment changes. Serious side effects are rare.
  • Behavioral disorders may also require the use of additional medications, daily modifications to routine, environmental changes, supplements, or other medical therapies.

Ingredients

Instructions

FAQ

Learn More About Amitriptyline From Our Team of Experts
4.5
Rated 4.5 out of 5 stars
190 Ratings

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

89% Positive

Effectiveness

85% Positive

Ingredients

83% Positive

Long-Term Benefits

91% Positive

68 Customer Reviews



Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 3 out of 5 stars
By Kaitlyn on Feb 10, 2026

Don't know if it works...

I honestly don't know if this is even working. I seclude the cat for most of the day in her own room (it's decked out to the highest degree) and that has made a

I honestly don't know if this is even working. I seclude the cat for most of the day in her own room (it's decked out to the highest degree) and that has made a significant difference. As for the meds, I don't really notice any difference in her attitude/mental state. She's still a pretty nervous cat


Rated 1 out of 5 stars
By Laura on Dec 10, 2025
Top 1000 Contributor

Doesn't help my dogs anxiety

My dog Winter has been taking this for a couple months. I thought at first it was helping but it really isn't. She is so skittish and I was so hopeful this would

My dog Winter has been taking this for a couple months. I thought at first it was helping but it really isn't. She is so skittish and I was so hopeful this would help. She's terrified of everyone and basically anything that moves. You move a box to quickly and she jumps out of her skin. I tried fluoxetine first and that did nothing. Next my vet wants her to try clomipramine. Hopefully that does something!


Rated 5 out of 5 stars
By Lee on Feb 6, 2026

Way, way less than I can get it rm th

Actually seems to b helping his anxiety, and as I can’t get it for a reasonable price at the Vet, chewy makes it extremely easy and affordable.

Actually seems to b helping his anxiety, and as I can’t get it for a reasonable price at the Vet, chewy makes it extremely easy and affordable.


Rated 5 out of 5 stars
By Bernadette on Dec 2, 2025

Color and size

Easy size to give and good color to see when he would spit it out. Unfortunately, this medication didn’t work for my cat, he’s still aggressive towards my other

Easy size to give and good color to see when he would spit it out. Unfortunately, this medication didn’t work for my cat, he’s still aggressive towards my other cat. I’m sure it’s worked for others. Good luck


Rated 2 out of 5 stars
By Pippen on Sep 20, 2025

Inconsistent quality

These are generic and come from various manufacturers. One manufacturer sends a pill that is ineffective and our cat starts right back into his inappropriate urinating

These are generic and come from various manufacturers. One manufacturer sends a pill that is ineffective and our cat starts right back into his inappropriate urinating within a few days. The other manufacturer seems legit and the results are consistent. And there’s no way to specify which you want so it’s luck of the draw and the times we get the bad ones we are in for a month of cleaning up urine everywhere and starting back from scratch when the next month’s supply comes. (And hoping it’s not from the same manufacturer)


Rated 1 out of 5 stars
By Cat on Oct 29, 2025

Major GI upset and Zero Behavior Change

Both dogs started having explosive diarrhea, my older dog even started vomiting and became lethargic. On top of the GI upset, the younger dog still wants to eat

Both dogs started having explosive diarrhea, my older dog even started vomiting and became lethargic. On top of the GI upset, the younger dog still wants to eat the stool and now even the vomit. Requesting refund from company, completely unsatisfied.


Rated 5 out of 5 stars
By Kathryn on Mar 5, 2026

Fast shipping, great price

Helping to keep my cat calm in order to prevent another UTI.

Helping to keep my cat calm in order to prevent another UTI.


Rated 5 out of 5 stars
By Cathy on Sep 12, 2025

Great price

These small coated pills must be cut in half for my little cat Cherise. The coating ensures that they don't break up or cut unevenly in the pill cutter. Chewy always

These small coated pills must be cut in half for my little cat Cherise. The coating ensures that they don't break up or cut unevenly in the pill cutter. Chewy always contacts my vet right away for refills on this med, and I always get the Rx in plenty of time. Will keep buying from Chewy, it is so easy and reliable.


Rated 5 out of 5 stars
By Debora on Dec 3, 2025

Home delivery

Lovely to be able to have the meds delivered to me now that two of my cats are on meds. Thank you, Chewy!

Lovely to be able to have the meds delivered to me now that two of my cats are on meds. Thank you, Chewy!


Rated 1 out of 5 stars
By Susan on Feb 1, 2026

Yes and no

It works for crumpet but not die Colby or mango. Sheesh.

It works for crumpet but not die Colby or mango. Sheesh.