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Advantage Topical Flea Prevention for Large Cats, 9 lbs+, 2-Monthly Treatments

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About This Item

Details

  • This topical flea prevention and treatment is designed for large cats 9+ pounds and at least 8 weeks of age.
  • The monthly topical treatment is easy to apply, and there are no hard-to-swallow pills.
  • The treatment works quickly, killing fleas within 12 hours of application.
  • Each treatment offers up to 30 days of protection for your furbaby.
  • The formula is fragrance-free, waterproof, and available without a prescription.

Ingredient Information

Instructions

Advantage for Cats

Advantage for cats topical flea prevention and treatment starts killing fleas within 12 hours of application. What’s more, one treatment prevents further flea infestations for four weeks—it kills fleas so they don’t lay eggs.

One Application Protects for 4 Weeks

Apply once a month according to the label instructions. The fragrance-free formula is waterproof and available without a prescription, so you don’t have to go to the vet to get quality flea protection for your cat.

How It Works

Advantage kills fleas on cats. It works fast to kill the fleas you see now and keeps working all month long to prevent further infestations. It’s treatment and prevention all in one.

Find the Right Dose for Your Cat

This topical flea treatment comes in two sizes: small cats (2-9 lbs.) and large cats (over 9 lbs.). Apply Advantage to your cat once every 4 weeks according to the complete directions for use on the product label.

About Advantage

The Advantage family of products has what you need for a complete flea treatment and prevention plan, including monthly topical treatments, pet shampoos and sprays, household sprays for carpets and crevices, and even a yard and premise spray.

Shop Advantage

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Questions & Answers

2 Customer Questions

can the cat groom himself immediately after treatment

Does this work for ticks as well?

Answer by Chewy • Nov 07, 2025
This product is only intended to help kill adult fleas on your cat before they lay new eggs.
Reviews
Write a Review
4.5
Rated 4.5 out of 5 stars
1033 Ratings
Terms & Conditions

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

80% Positive

Effectiveness

82% Positive

Ingredients

79% Positive

Long-Term Benefits

84% Positive

279 Customer Reviews

Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 5 out of 5 stars
By Rick on May 29, 2024
Received Free Product

Effective Real World Feline Flea Control

Our Vet specifically recommended Advantage products for both flea and tick control and we have been successfully using them on our four Indoor/Outdoor cat "family"

Our Vet specifically recommended Advantage products for both flea and tick control and we have been successfully using them on our four Indoor/Outdoor cat "family" for a number of years. My wife is the "bad guy" who applies the product and loves the ease of application. Less stress all around! Additionally, past products have irritated our cats skin and caused obvious discomfort but Advantage has not displayed these unwanted side effects. Lastly, and most importantly, this product has proven VERY effective for controlling fleas and, living in a densely timbered area, is imperative. Highly recommended even if your cat is an indoor pet as the old adage says: An ounce of prevention is worth a pound of cure!

Rated 5 out of 5 stars
By Angel on Nov 16, 2025

Customer Service

Apoquel works well for seasonal allergies although I'm not comfortable giving it to Max all year round and during low pollen seasons when he starts itching I bath

Apoquel works well for seasonal allergies although I'm not comfortable giving it to Max all year round and during low pollen seasons when he starts itching I bath him in Nizoral dandruff shampoo which is actually yeast and it works very well... Thankfully because my Vet went on vacation before approving Max's apoquel so I contacted Chewy for a refund because I'd ordered several different items and prepaid for all. I must say Chewy has an awesome Customer Service team!!!

Rated 3 out of 5 stars
By Kimberly on May 27, 2024
Received Free Product

Just okay

We have two colony cats that won't always let us pet them. In a recent show of affection I was able to apply the product easily without her higness knowing. I've

We have two colony cats that won't always let us pet them. In a recent show of affection I was able to apply the product easily without her higness knowing. I've seen a lot less scratching and I don't see any ticks. It has been less than a month since application so I am crossing fingers it continues to provide comfort even if its marginal.

Rated 5 out of 5 stars
By Sherry on Jul 24, 2025

Preventive care at a fair price

Friend came to visit with a flea infested dog. Our cats are indoor and have never had fleas. When they started scratching the very next day, I had to get them relief

Friend came to visit with a flea infested dog. Our cats are indoor and have never had fleas. When they started scratching the very next day, I had to get them relief. I put this on them and no more scratching. I will be ordering and treating them again next month to make sure.

Rated 5 out of 5 stars
By Deborah on Nov 17, 2024

It WORKED!!

I was thrilled that, this was Easy to apply, and, it WORKED!! ( My Cats had never had fleas, in their entire 6+years, and, then, (because I rescued a cat---- Bam!)

I was thrilled that, this was Easy to apply, and, it WORKED!! ( My Cats had never had fleas, in their entire 6+years, and, then, (because I rescued a cat---- Bam!) Now, No Fleas!! No "digging at themselves", and, nobody got sick from the tx!

Rated 1 out of 5 stars
By Joyce on Jun 8, 2025

Flea and tick box empty

The delectable box was squashed and so was the Advantage I found the directions under Litter but no tubes .I appreciate the discount but I think maybe 40 lbs of

The delectable box was squashed and so was the Advantage I found the directions under Litter but no tubes .I appreciate the discount but I think maybe 40 lbs of litter did a little damage .Thank you

Rated 4 out of 5 stars
By Betty on Jan 1, 2025

Good products but wrong one

I ordered Advantage II, and got the original Advantage. Advantage II kills flea eggs, flea larvae, and ticks, as well as adult fleas. But original Advantage only

I ordered Advantage II, and got the original Advantage. Advantage II kills flea eggs, flea larvae, and ticks, as well as adult fleas. But original Advantage only kills adult fleas. My cat has had ticks before and I really needed Advantage II. But the products are good, other than the mixup about what I got.

Rated 3 out of 5 stars
By Rose on May 1, 2026

Poor delivery and packaging

Yet again. This came almost squished at the bottom of the litter and I was shocked it didn’t pop the medicine. I complained about delivery men so much I don’t think

Yet again. This came almost squished at the bottom of the litter and I was shocked it didn’t pop the medicine. I complained about delivery men so much I don’t think it makes a difference. I fear for the day a product is just spilled everywhere. Also this is not effective as revolution but I supplement it with natural flea repellent

Rated 5 out of 5 stars
By Debra on Dec 26, 2025

Good price and it works

This flea prevention is reasonably priced and works for my indoor/outdoor cat. I have tried to keep him indoors, however he is a professional escape artist so he

This flea prevention is reasonably priced and works for my indoor/outdoor cat. I have tried to keep him indoors, however he is a professional escape artist so he brings things home. This treatment works well for us.

Rated 5 out of 5 stars
By Michele on Nov 24, 2025

No More Fleas

This worked so fast and amazing. I saw a difference as soon as I put it on my cats and they have no more fleas. Highly recommend

This worked so fast and amazing. I saw a difference as soon as I put it on my cats and they have no more fleas. Highly recommend