Advantage Multi Topical Solution for Dogs, 20.1-55 lbs, (Red Box), 6 Doses (6-mos. supply)

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Medications ship separately. Delivery times may vary.

About This Item

Details

  • Advantage Multi provides 6-in-1 protection from fleas, heartworms, roundworms, hookworms, whipworms, and sarcoptic mange.
  • One monthly dose kills worms all month long.
  • Kills fleas through contact; pests don�t have to bite your dog to die
  • Treats & controls roundworms, hookworms & whipworms
  • Easy-to-apply topical treatment, no hard-to-swallow pills. Perfect for patients that struggle with oral medications.

Ingredients

Instructions

FAQ

Learn More About Advantage Multi From Our Team of Experts
4.7
Rated 4.7 out of 5 stars
904 Ratings

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

92% Positive

Effectiveness

92% Positive

Ingredients

90% Positive

Long-Term Benefits

90% Positive

304 Customer Reviews



Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 5 out of 5 stars
By Terry on Sep 28, 2025

Came right on time!!

When I “fostered” Josie, she was part of a hoarding situation that was broken up and she looked the worse, skinny and ill looking. She was scared to death of humans

When I “fostered” Josie, she was part of a hoarding situation that was broken up and she looked the worse, skinny and ill looking. She was scared to death of humans (and still kind of is). Anyway, foster fail and loving that imp everyday!! Oh yea, and she had almost every parasite in her gut, thus the Adv Multi. I’m so glad she is my (2nd) foster fail!!


Rated 5 out of 5 stars
By barbie on Jul 20, 2018

LOVE this product

i know that some products don't work for every pet but my dog has been on this brand for 6 months now and we have had no issues at all. currently i purchase 1 dose

i know that some products don't work for every pet but my dog has been on this brand for 6 months now and we have had no issues at all. currently i purchase 1 dose at a time from my vet for a much bigger price than the deal that chewy is offering, so as soon as the next treatment comes up for my dog i will be ordering from this site. originally my dog was on revolution which worked just as well but my vet stopped using that brand and switched to advantage multi as he only offers one flea brand to his clients. i will also be purchasing the 6 month treatments of this brand for my other 3 dogs as well (different weights). i hope this helps out with anyone wondering if it will work for their pet. remember not every brand will work on every animal.


Rated 5 out of 5 stars
By Julia on Jun 13, 2025

Advantage Multi Saved My Dog's Life

My heart dog came to me from a rescue in May of 2024. They diagnosed him HW+ there and treated him with the melarsomine injections. Many months later he was still

My heart dog came to me from a rescue in May of 2024. They diagnosed him HW+ there and treated him with the melarsomine injections. Many months later he was still testing HW+ and his vet had determined the treatment had failed. After a long discussion of re-treating vs. not, we elected to visit a cardiologist to ensure his heart was in good condition and give the moxi-doxy protocol a shot. Well, 4 months later he is 100% HW free! He's been able to try all sorts of things that he wasn't able to due to previous exercise restrictions like dock diving, agility, and more! I credit this preventative for helping my dog completely clear his heartworm disease.


Rated 5 out of 5 stars
By MummyOfTubby on Aug 7, 2020

Better than all the rest!

Before Advantage Multi, my dog had only ever been protected by two other multipurpose topicals (each one covered both worms and fleas). However, one summer, there

Before Advantage Multi, my dog had only ever been protected by two other multipurpose topicals (each one covered both worms and fleas). However, one summer, there was this really rare parasite of the nose that my dog contracted and the Vet put him on Advantage Multi to kill that nasal parasite. Since then my dog has been protected from heartworm, intestinal worms, fleas AND one very uncommon parasite that isn’t even listed on this box...all while I benefit from the lower price (compared to the competition)!


Rated 5 out of 5 stars
By Glenn on Feb 26, 2026

CHEWY heart worm medication

Had a great experience ordering from Chewy and the prices were cheaper than other vendors. Everything is much more expensive these days but I found a good deal from

Had a great experience ordering from Chewy and the prices were cheaper than other vendors. Everything is much more expensive these days but I found a good deal from a trusted company and my pet is healthy and happy!


Rated 5 out of 5 stars
By Cindy on May 16, 2025

Ease of use

I had a terrible time giving both of my dog's pills! I've been fighting it for 4 years recently I broke my wrist and couldn't pick them up to put them on a counter

I had a terrible time giving both of my dog's pills! I've been fighting it for 4 years recently I broke my wrist and couldn't pick them up to put them on a counter to force the pills down their throat with one hand cuz it was my dominant wrist. When I explain to the doctor that I just can't do this anymore he asked me to try this new one advantix multi it's so easy to put on they don't mind so it makes my life easier because their life is better


Rated 5 out of 5 stars
By LORIE on Nov 11, 2023

Topical application for dogs with meat flavor allergies.

My dog has meat flavor allergies so she can’t take oral heartwoom medicine. This product allows me to give her heart worm protection. She has short hair and there’s

My dog has meat flavor allergies so she can’t take oral heartwoom medicine. This product allows me to give her heart worm protection. She has short hair and there’s a lot of liquid for one application so I apply small amounts and let it soak in over a period of time. If you don’t it runs in areas she could lick.


Rated 5 out of 5 stars
By Evelyn on Feb 9, 2026

Great alternative

My dog is s cluster seizure epileptic. All the oral heartworm, anti flea prescriptions cause seizures. This is a great alternative

My dog is s cluster seizure epileptic. All the oral heartworm, anti flea prescriptions cause seizures. This is a great alternative


Rated 5 out of 5 stars
By Mary on Mar 26, 2026

easy to apply , does irritate skin

We walk everyday , and i've never had a flea or tick attach to him . Effective in mosquitoes also

We walk everyday , and i've never had a flea or tick attach to him . Effective in mosquitoes also


Rated 4 out of 5 stars
By Tanya on Nov 10, 2025

Hookworms

Cleadus was infested with hook worms and it took meds and Advantage to get rid of them.

Cleadus was infested with hook worms and it took meds and Advantage to get rid of them.