Advantage II Flea Spot Treatment for Cats, 5-9 lbs, 2 Doses (2-mos. supply)

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About This Item

Details

  • Flea protection for small cats weighing 5 to 9 pounds, at least 8 weeks of age.
  • Easy-to-apply monthly topical treatment.
  • Delivers total flea protection and kills adult fleas, flea larvae and flea eggs through contact.
  • Starts killing fleas the same day and keeps working for 30 days.
  • Fragrance-free formula is waterproof after 24 hours of application.

Ingredients

Instructions

Size

FAQ

Learn More About Advantage II From Our Team of Experts

Important Information

Fleas rise to the top of your pet's coat as they die, so consider it a triumph if you start seeing more fleas at first, after treating your pet. If you’re still seeing fleas after application, it may be because your pet has picked up new fleas from the environment, which may include other pets, surfaces and outdoor areas. It may take up to 30 days to break the entire flea life cycle. Additionally, you should also treat sources of new fleas (i.e., carpet, yard, etc.) to ensure complete flea control.

About Advantage II for Cats

Get the Advantage Over Fleas

Advantage II topical flea treatment and prevention for cats kills fleas on your cat within 12 hours, and it continues to protect for 30 days. It’s easier to use than hard-to-swallow pills—simply apply the convenient flea drops directly to your cat's skin once a month. Best of all, Advantage II is available without a prescription.

Flea Treatment and Prevention

Advantage II doesn't just treat fleas––it breaks the flea lifecycle to prevent reinfestation.

Works Through Contact

These flea drops kill adult fleas, flea larvae, and flea eggs through contact, so they don't have to bite your cat to die.

Same-Day Effectiveness

Advantage II starts killing fleas on cats within 12 hours, and it continues to prevent reinfestations for four weeks.

No Prescription Needed

You don’t have to go to the vet to get quality flea protection for your cat—simply buy and apply.

Fragrance-Free

This flea topical formula is fragrance-free and waterproof 24 hours after application.

Frequently Asked Questions

Can I Use Advantage II on My Cat?

Advantage II is for cats and kittens 8 weeks of age and older. It comes in three sizes: Kitten (2-5 lbs.), Small Cat (5-9 lbs.), and Large Cat (9+ lbs.). Choose the right size based on your pet's weight. Advantage II for cats is suitable for both indoor and outdoor cats, but not for use on dogs.

How Do I Apply Advantage II?

Once you break the seal on the tube, part the hair at the base of your cat’s skull until the skin is visible. Squeeze the tube to expel the entire contents directly onto the skin in that one spot. Do not get this product in your cat’s eyes or allow your cat to ingest it.

The Advantage Family

Get the Advantage over fleas with complete flea protection for your pet, home, and yard. The Advantage family of products has everything you need for a complete flea treatment and prevention plan, including monthly topical treatments, pet shampoos and sprays, household sprays for carpets and crevices, and even a yard and premise spray. Just be sure to get the right product for each need and use only as directed.

Shop K9 Advantix II

Questions & Answers

31 Customer Questions


I bought this for my 7 pound cat and it never worked. The only thing that’s working for her is capstar and that’s all we’re buying from now on. Can I get my money back please? It was suggested to me by a vet you have there. I thought it would work since she had suggested it. It never got rid of any.


how many cc are in one application tube?

Answer by ChewyAug 04, 2018
Each application tube contains 0.4 cc.

Does Advantage 2 protect against mosquitoes also?

Answer by ChewyJun 16, 2018
This product has not been tested to repel mosquitoes.

Does this product kill worms?

Answer by ChewyJan 25, 2021
This treatment does not kill worms, it is formulated to kill fleas and ticks.

4.5
Rated 4.5 out of 5 stars
4907 Ratings

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

82% Positive

Effectiveness

82% Positive

Ingredients

79% Positive

Long-Term Benefits

82% Positive

2066 Customer Reviews



Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 2 out of 5 stars
By Joann on Apr 2, 2026

Always worked before

Sll 3 cats still had fleas. I called the company and asked if they'd changed the formula since they bought out Bayer. They said no and sent me 2 free boxes. Still

Sll 3 cats still had fleas. I called the company and asked if they'd changed the formula since they bought out Bayer. They said no and sent me 2 free boxes. Still have fleas after using theirs. Something's wrong. I have used Advantage since it came on the market in the 90s snd it always worked! This does not. Not Chewys fault, don't give me a refund


Rated 1 out of 5 stars
By Karen on Mar 30, 2026

FLEAS!

Idk if it's Tex or what. Started with Frontline not working yrs ago, the hunt was on. I can't afford any more than A2. She or the others never had a day relief

Idk if it's Tex or what. Started with Frontline not working yrs ago, the hunt was on. I can't afford any more than A2. She or the others never had a day relief. Not Chewy's fault. We used to at least have 2-3 months winter off. Not anymore they breed all yr!


Rated 5 out of 5 stars
By Yeshuan on Mar 12, 2026

Only brand that works

This one. Not the other advantage products. NEVER use the 2-month stuff unless you have a shaggy cat, because it's just extra liquid. This is the only thing that

This one. Not the other advantage products. NEVER use the 2-month stuff unless you have a shaggy cat, because it's just extra liquid. This is the only thing that keeps the fleas away and she never goes outside, so if she keeps the couple fleas WE HUMANS bring in with the other junk medicine, you know this works better.


Rated 5 out of 5 stars
By Lorna on Feb 6, 2026

So many orders

Lately I have so many orders I never know which one you are asking about. On the FLEA meds, I got them late because of crazy snow storms. That is mother nature

Lately I have so many orders I never know which one you are asking about. On the FLEA meds, I got them late because of crazy snow storms. That is mother nature and keeping people safe is the most important. I have no problem with that. Have not used the product yet. On the Rx wet food. I requested the case be protected from dents the way you all used to do it. Came nicely protected and I have not started that case yet, but I don't see huge dents in the can. So looking good. The cat lids did not fit my 5.5 cans of any of my foods. I donated them to the Vets office with the Senvelgo Rx in Chewy's name. Thank you again.


Rated 4 out of 5 stars
By Giovanni on Feb 22, 2026

Works well for the price.

My cat didn’t have any issues with the application of this product, as long as you put it behind their neck so they can’t lick it off themselves. I also suggest

My cat didn’t have any issues with the application of this product, as long as you put it behind their neck so they can’t lick it off themselves. I also suggest you put it on them early in the morning after they wake up so they don’t go to sleep and roll over and rub it off their back on your furniture or carpet.


Rated 3 out of 5 stars
By Lyn on Jan 14, 2026

Very small 18"

This is a very nice burrow for cats but it is very small and my cats are large. I followed suggestions in other reviews and cut the closed end out. My cats play

This is a very nice burrow for cats but it is very small and my cats are large. I followed suggestions in other reviews and cut the closed end out. My cats play with it and one cat grab the toy and ran to the house with the tunnel and toy. It was cracka because the other cat was chasing her. It's probably more designed for kittens. I have a large 7 lb cat very long and she hasn't gone in inside of it except for one. 10 lb already and she's a little bit leery about going inside also because it's so small. By cutting the closed and off they had more interest in it. If you have large cats I suggest not to buy this toy.


Rated 1 out of 5 stars
By Suzanne on Mar 20, 2026

30 off 100

I was to get $30 Off called and lady said it would come off next order. Ordered another $100 and received $30 But on my 3rd order that eas sent to a charity did

I was to get $30 Off called and lady said it would come off next order. Ordered another $100 and received $30 But on my 3rd order that eas sent to a charity did not receive $30 off order. Bait and switch


Rated 5 out of 5 stars
By CINDY on Feb 7, 2026

Option to purchase in a single dose or more which saves money.

This product works. Allow 10-14 days for results. No flea treatment is magic and a flea issue on a pet does not resolve itself over night. Remember Fleas have 3

This product works. Allow 10-14 days for results. No flea treatment is magic and a flea issue on a pet does not resolve itself over night. Remember Fleas have 3 stages Adult/Larvae/Flea Eggs that repeats itself until managed by product. Be faithful and apply at or near same date monthly year round.


Rated 5 out of 5 stars
By Tammy on Apr 4, 2026

It’s always a great product

I’ve been using this for years and I’ve never had any issues. It’s the best for us at fighting off the fleas for my indoor cats.

I’ve been using this for years and I’ve never had any issues. It’s the best for us at fighting off the fleas for my indoor cats.


Rated 5 out of 5 stars
By Jamie on Feb 23, 2026

Works well

This product works great for my outdoor cats, however, I do not like how chewy sends it with other things because it's always smashed and the little containers are

This product works great for my outdoor cats, however, I do not like how chewy sends it with other things because it's always smashed and the little containers are all throughout the box.