Advantage II Flea Spot Treatment for Cats, over 9 lbs, 6 Doses (6-mos. supply)

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About This Item

Details

  • Flea protection for cats weighing over 9 pounds, at least 8 weeks of age.
  • Easy-to-apply monthly topical treatment.
  • Delivers total flea protection and kills adult fleas, flea larvae and flea eggs through contact.
  • Starts killing fleas the same day and keeps working for 30 days.
  • Fragrance-free formula is waterproof after 24 hours of application.

Ingredients

Instructions

Size

FAQ

Learn More About Advantage II From Our Team of Experts

Important Information

Fleas rise to the top of your pet's coat as they die, so consider it a triumph if you start seeing more fleas at first, after treating your pet. If you’re still seeing fleas after application, it may be because your pet has picked up new fleas from the environment, which may include other pets, surfaces and outdoor areas. It may take up to 30 days to break the entire flea life cycle. Additionally, you should also treat sources of new fleas (i.e., carpet, yard, etc.) to ensure complete flea control.

About Advantage II for Cats

Get the Advantage Over Fleas

Advantage II topical flea treatment and prevention for cats kills fleas on your cat within 12 hours, and it continues to protect for 30 days. It’s easier to use than hard-to-swallow pills—simply apply the convenient flea drops directly to your cat's skin once a month. Best of all, Advantage II is available without a prescription.

Flea Treatment and Prevention

Advantage II doesn't just treat fleas––it breaks the flea lifecycle to prevent reinfestation.

Works Through Contact

These flea drops kill adult fleas, flea larvae, and flea eggs through contact, so they don't have to bite your cat to die.

Same-Day Effectiveness

Advantage II starts killing fleas on cats within 12 hours, and it continues to prevent reinfestations for four weeks.

No Prescription Needed

You don’t have to go to the vet to get quality flea protection for your cat—simply buy and apply.

Fragrance-Free

This flea topical formula is fragrance-free and waterproof 24 hours after application.

Frequently Asked Questions

Can I Use Advantage II on My Cat?

Advantage II is for cats and kittens 8 weeks of age and older. It comes in three sizes: Kitten (2-5 lbs.), Small Cat (5-9 lbs.), and Large Cat (9+ lbs.). Choose the right size based on your pet's weight. Advantage II for cats is suitable for both indoor and outdoor cats, but not for use on dogs.

How Do I Apply Advantage II?

Once you break the seal on the tube, part the hair at the base of your cat’s skull until the skin is visible. Squeeze the tube to expel the entire contents directly onto the skin in that one spot. Do not get this product in your cat’s eyes or allow your cat to ingest it.

The Advantage Family

Get the Advantage over fleas with complete flea protection for your pet, home, and yard. The Advantage family of products has everything you need for a complete flea treatment and prevention plan, including monthly topical treatments, pet shampoos and sprays, household sprays for carpets and crevices, and even a yard and premise spray. Just be sure to get the right product for each need and use only as directed.

Shop K9 Advantix II

Questions & Answers

52 Customer Questions


Since advantage has made a step up from this product, thats why this one that has worked for years now doesnt work? So disappointing. I used to count on Advantage.

Answer by mabengirl1965Mar 04, 2026
Anytime you use the same treatment every month, the fleas, eggs, and larvae become immune to the treatment. I usually change my routine every other month or two so that there is a little chance for this to happen.

My cat is scratching and itching after treatment, and not from fleas. Have any other cats experienced this?


Since the product is applied to your cats neck, what about the fleas on the cats belly will they move to the neck?

Answer by ChewySep 19, 2017
The active ingredients of Advantage II work to attack the fleas, no matter where they're located on your cat.

can you use before 30 days is up

Answer by ChewyMay 15, 2021
Under normal conditions this product is effective for one month. However, in cases of severe flea infestation, retreatment may be necessary earlier than 4 weeks. Do not retreat more often than once every 14 days for kittens or once every 7 days for small and large cats. After flea control is attained, return to a monthly retreatment schedule.

4.5
Rated 4.5 out of 5 stars
11323 Ratings

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

83% Positive

Effectiveness

82% Positive

Ingredients

80% Positive

Long-Term Benefits

83% Positive

4736 Customer Reviews



Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 5 out of 5 stars
By Beth on Jan 15, 2025

Happy Cats!

I prev. Used Advantage lol for both my cats. And I chg to another product for a yr. Now I’m back hoping they have made changes to fix their product. I’ve only had

I prev. Used Advantage lol for both my cats. And I chg to another product for a yr. Now I’m back hoping they have made changes to fix their product. I’ve only had them on it for a short few weeks. So far so good! Both my cats appear to be happy w the results. I haven’t seen either Cat scratching - not once! So this is Wonderful! So long as their product works to protect them from fleas. I will continue to keep ordering it. As far as Chewy. I couldn’t be happier w/ how nice their Customer Service on the phones are. Ordering was so nice n easy. It was a Blessing to receive a Gift Certificate, which helped me with my order. I’m on Disability since 2013 & a Senior! So any break I can get helps me to afford to purchase the supplies I need to keep my pets healthy n happy!Thank you Chewy for helping your customers with a discount of sales, and or gift certificates regularly! Thank you for the support n super fast delivery! I plan on staying with you for years!

By Beth on Jan 15, 2025

Rated 5 out of 5 stars
By Michael on Jun 6, 2025

Quick delivery

You guys are a great company! My cat of almost 16 years passed and she died unexpectedly from what they thought was a brain tumor. She was due for an auto-ship

You guys are a great company! My cat of almost 16 years passed and she died unexpectedly from what they thought was a brain tumor. She was due for an auto-ship of her food and when I called to cancel the phone rep was so apologetic and the. I received a beautiful bouquet of flowers from Chewy soon after. I was so surprised and heart filled appreciation. Very few companies would do that but Chewy did. Thank you and you have a customer for life, especially showing me that level of kindness!

By Michael on Jun 6, 2025

Rated 5 out of 5 stars
By Cynthia on Sep 16, 2025

22lb Monster of Cat

I use this for my extra-large cat. My smaller cats have been using a different brand. I see fleas come back on them after about 3 weeks from application. This one

I use this for my extra-large cat. My smaller cats have been using a different brand. I see fleas come back on them after about 3 weeks from application. This one has been lasting 4-5 weeks, even with fleas starting to get on the others. The price on this one was better than the other main brands for large cats. I will be buying again, but adding the lower weight doses too for the smaller ones.

By Cynthia on Sep 16, 2025

Rated 5 out of 5 stars
By Lawrence on Apr 16, 2026

Works great

I have 4 inside cats, one would lick and take all her hair off from the last half of her body. I thought she was just a nervous nelly. And one other cat that would

I have 4 inside cats, one would lick and take all her hair off from the last half of her body. I thought she was just a nervous nelly. And one other cat that would dig himself around his flea collar and get bad sores. This advantage 11 for cats except I buy the 6 pk has done wonders for them. Fluffy has grown all her hair back over the last few months and cookie has no sores.

By Lawrence on Apr 16, 2026

Rated 5 out of 5 stars
By Cynthia on Jul 11, 2025

It works

One of my outdoor cats had something on his eye next to his tear duct for about a week, He’s very skittish and will not let me get near him to see what it was, turns

One of my outdoor cats had something on his eye next to his tear duct for about a week, He’s very skittish and will not let me get near him to see what it was, turns out it was a tick and growing. It was a little past due to get the treatment so I applied it and within two days that tick fell off. I’m Very happy to know it worked that quickly.

By Cynthia on Jul 11, 2025

Rated 5 out of 5 stars
By Audry on Sep 19, 2024

Actually available for shipping to my address

I have 28 cats. I buy flea treatment 2-3 times a year. Another online store limits how much I can buy telling me I must not be applying it correctly if I need to

I have 28 cats. I buy flea treatment 2-3 times a year. Another online store limits how much I can buy telling me I must not be applying it correctly if I need to buy more. I only buy during flea season, but I buy for each pet. Trying to explain this to the overseas switchboard that barely speaks English is crazy. I remembered that Chewy also had drops as well as treats and food. I ordered what I needed and wasn't even questioned about it. "Here ya go ma'am thank you for your order." If I get the extra time, I'll fill out a cute little profile for each one of my pets ;) Thanks Chewy ;D

By Audry on Sep 19, 2024

Rated 1 out of 5 stars
By William on Jul 26, 2025

Does not work

I have four cats. Three of my cats are larger, and one cat that's a year old is much smaller. I had to buy two different weight classes of flea medicine due to that

I have four cats. Three of my cats are larger, and one cat that's a year old is much smaller. I had to buy two different weight classes of flea medicine due to that fact. I have been giving this flea medicine to my cats for a while now, and their fleas have gotten worse. I would never buy this product again nor would I refer this product to anyone. I also use the same name brand products but of a cat flea shampoo alongside the topical treatment. Once again let me repeat what I'm saying. Not only did I use the topical treatment I have been bathing them in the same name brand of flea shampoo, and their fleas have gotten worse on all four cats.

By William on Jul 26, 2025

Rated 5 out of 5 stars
By Karen on Oct 14, 2025

Total nuisance control

I used to use front line and all my animals doesn’t work anymore. I think the animals have become immune to it or the ticks and fleas are but Iuse advantage now

I used to use front line and all my animals doesn’t work anymore. I think the animals have become immune to it or the ticks and fleas are but Iuse advantage now don’t have a problem. I never had a problem and I don’t plan on having more problems, I’m faithful every month. I ordered boxes a year And I’m on top of it. Thanks. Chewy great prices

By Karen on Oct 14, 2025

Rated 5 out of 5 stars
By Terrie on Apr 12, 2025

Worked great

This wasn't my vets first choice but we have always used this one over the years and had zero problems. My cats stay in doors so we don't really have a flea problem

This wasn't my vets first choice but we have always used this one over the years and had zero problems. My cats stay in doors so we don't really have a flea problem. We have a dog now and we think he brought in fleas. We have one FIV cat that stays in the master bedroom and that area was infested and I've never seen so many fleas on a cat. After a bath and one treatment with daily flea combs we all flea free.

By Terrie on Apr 12, 2025

Rated 5 out of 5 stars
By Carol on Dec 30, 2025

A necessary evil

I hate the fact I have to put chemicals on my cat. But in the south, you have too. I tried "natural" methods and they don't work. I do not let my cat roam outside,

I hate the fact I have to put chemicals on my cat. But in the south, you have too. I tried "natural" methods and they don't work. I do not let my cat roam outside, but he does enjoy the screened porch. Also, I'm sure I introduce sand fleas in the house just working in my yard. When I was on my "natural" kick, he had scabs various places on his body from fleas. DE dried his skin horrible. Regular baths dried him out and he even got a respiratory infection in the AC from being wet. Advantage is the only way to go. Keeps him flea/scab free. Keeps me scratch free from the baths.

By Carol on Dec 30, 2025