Adequan Canine (polysulfated glycosaminoglycan) Injectable for Dogs, 100-mg/ml, 5-mL, 2 count

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About This Item

Details

  • Used to help manage degenerative joint conditions
  • Helps address lameness associated with joint dysfunction
  • Contains polysulfated glycosaminoglycan (PSGAG)
  • PSGAG is described as a semi-synthetic glycosaminoglycan
  • Veterinary injectable joint therapy

Ingredients

Instructions

FAQ

Learn More About Adequan Canine From Our Team of Experts
4.7
Rated 4.7 out of 5 stars
2095 Ratings

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

91% Positive

Effectiveness

92% Positive

Ingredients

89% Positive

Long-Term Benefits

92% Positive

890 Customer Reviews



Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 5 out of 5 stars
Verified Purchase
By Holly on Jul 26, 2025

LOVE Chewy!

Chewy is such an amazing company that truly has animal's best interests at heart. My 9 year old Staffy has CCL tears in both knees. He aged 5 years overnight and

Chewy is such an amazing company that truly has animal's best interests at heart. My 9 year old Staffy has CCL tears in both knees. He aged 5 years overnight and can no longer go on walks longer than 5 minutes. It is heartbreaking, and the worst thing is that I'm pretty sure it was our wood floors that did it to him. I have had heard wonderful things about Adequan and we just started our loading rose of 2 shots a week for 4 weeks. If anyone would have told me that I would be giving my baby injections myself, I most certainly would have though they were crazy...but as pet parents we do what we have to for our babies. Luckily as long as dad is petting him and giving him treats, he doesn't even notice that I'm doing it. I am PRAYING that this medication helps. Just in case I have already been pricing wheel chairs for him which is around $150 which is less than his medication but I would much rather have him mobile himself. Fingers crossed that it helps. We just went through treatment for a Madt cell tumor and now this.


Rated 5 out of 5 stars
Verified Purchase
By Jorge on Apr 25, 2025

We believe in this product

Brook Noodles was born as the vet put it " she was born with all bad wheels " As a pup she had elbow dysplasia surgery, she could not even run as a pup at times

Brook Noodles was born as the vet put it " she was born with all bad wheels " As a pup she had elbow dysplasia surgery, she could not even run as a pup at times prior to surgery. The healed from that. Yeah and a half go by and her knees start acting up specially the left on day her right one just goes... TPLO time... she is on her last weeks of healing and yeah we have to do the other one. So she started this med about a year ago plus carprofen which I slowed down on and gabapantin which I'm also not giving her daily anymore. Today she gets her shot of adequan. Ever since she started ( although it took a bit to start working it feels like ) she is so much happier and living a great life, I recommend you ask your vet if your dog has orthopedic problems. I can't even handle needles but for her I will do what I have to do !


Rated 5 out of 5 stars
Verified Purchase
By Christine on Dec 7, 2025

This medication is absolutely incredible!

My dog is a 100lb silver Labrador Retriever who is 9yrs old and has had both rear knees replaced and has generalized arthritis throughout her joints and spine. We

My dog is a 100lb silver Labrador Retriever who is 9yrs old and has had both rear knees replaced and has generalized arthritis throughout her joints and spine. We have done everything to help decrease her pain we tried: pain meds, water therapy, exercises, acupuncture, massage and chiropractics but she kept getting worse. I then took her to our Vet again and she recommended trying Adequan. It is expensive but I couldn’t pass up a chance to help her. Within a few hours after the injection she seemed to be getting up a bit easier but I thought that was impossible. The next day and I am being truly honest about this, she wanted to go outside and play ball toss. I threw the ball and she actually ran, she really ran to chase the ball!!!! She is doing so well on this medication it’s amazing! I only wish that this could be prescribed for people. Truly wonderful results! Chewy’s price is very good even though it’s still expensive but seeing my dog get around so much easier is worth it!


Rated 5 out of 5 stars
Verified Purchase
By Tony on Sep 25, 2025

Let's Romp!

My "boy" is 13 years old going on 2. It's only recently he's starting to show his age. One day I saw him limping and it got worse. My Vet and I talked about Adequan,

My "boy" is 13 years old going on 2. It's only recently he's starting to show his age. One day I saw him limping and it got worse. My Vet and I talked about Adequan, a medication I'm well familiar with. It took about a week, literally, and results happened. He's been on it now for a month and no more limping. He's back to romping in the dog park and sniffing everything interesting. I'm eternally grateful for Adequan. I wish they had something like this for humans.


Rated 5 out of 5 stars
Verified Purchase
By Audrey on Feb 2, 2026

Chewy customer service is very caring!

I can see they don't need another review as they have so many but I just wanted to say thank you to Chewy! I bought a product for my dog who was 13 years old in

I can see they don't need another review as they have so many but I just wanted to say thank you to Chewy! I bought a product for my dog who was 13 years old in hopes to make his last weeks good but waited too long and our family dog passed before I could give him the meds. I called to return and get my money back. She was so kind, gave the money back, did not ask me to ship the meds back, and I just couldn't believe it but they delivered flowers to my door!!! AMAZING! I wouldn't have expected it from any company really, but they are a large company and they still really do care about their customers! It was very thoughtful and I am grateful to have received the flowers in such a hard time. Thank you Chewy!


Rated 5 out of 5 stars
Verified Purchase
By Susan on Sep 2, 2025

Amazing results!

I ordered Adequan for my 11 year old lab. He has arthritis in all 4 legs. After just 3 injections we observed a difference in his behavior. He gets up with more

I ordered Adequan for my 11 year old lab. He has arthritis in all 4 legs. After just 3 injections we observed a difference in his behavior. He gets up with more ease and has been more playful with his toys. He also does zoomies on the lanai! We are hoping this will take him into his teen years. Very happy we gave Adequan a try.


Rated 5 out of 5 stars
Verified Purchase
By Cecil on Oct 22, 2025

Instant Puppy

After just one shot she was already walking better, after a few days her getting up off the floor was really better, she has now had a second stater shot and now

After just one shot she was already walking better, after a few days her getting up off the floor was really better, she has now had a second stater shot and now she is jumping back on the bed at night, she hasn't done that in a year, my puppy is back, whata wonder drug.


Rated 5 out of 5 stars
Verified Purchase
By Linda on Apr 23, 2026

Very helpful for bad hips

Our 12 yr old corgi, Pinot, was diagnosed in 2021 with hip dysplasia. Since 2024 he's been getting Adequan injections. In the past 6 months his movement is worse,

Our 12 yr old corgi, Pinot, was diagnosed in 2021 with hip dysplasia. Since 2024 he's been getting Adequan injections. In the past 6 months his movement is worse, more hind end weakness and more hind end slipping. When I give him an injection the benefit shows within a few hours. He walks better. At times on his walks he is like "speed racer"! He has a wagon now for when he tires. But some days he manages to walk a mile without needing a ride. I definitely recommend this product.


Rated 4 out of 5 stars
By SweetReen on Sep 3, 2021

MOST VETS PRESCRIBE THIS DRUG INCORRECTLY

Do your research before agreeing to your vet prescribing this series and then something like 2x or 1x a month for life. I recently called American Regent who owns

Do your research before agreeing to your vet prescribing this series and then something like 2x or 1x a month for life. I recently called American Regent who owns adequan directly to ask about their expiration date because my dog was now on a monthly injection, and it appears that the product expires 28 days after first puncturing the vial. This would mean that I would get 1 single-dose and 3 wasted. Very expensive! The representative explained that after 28 days, the vial is no longer sterile and that it's not safe to inject your dog. ALSO adequan cannot exceed 8 consecutive doses and should not be used 1x a month. The way it works is adequan leaves your pet's body in 3 days after the injection. When you do a series of monthly injections (2x a week for 4 weeks), the product builds up in their joints. Also, if your dog has no adequate cartilage, it is useless, so be sure to ask your vet what they see on X-rays? Is there a narrow space between the joints? Is it bone on bone? Because you're wasting your money that way. The way the maintenance works is by doing 2-3 series a year. This product is safe when used the way the manufacturers intended. It is not safe to use this product for longer than 8 injections without a substantial break in between. My dog's BUN was increased (she gets routine blood, stool, and urine test twice a year, and I've never had any issues). Vets buy Adequan and then just create their own way of how it works. We were put on the protocol of 2x a week for 4 weeks, 1x a week for 4 weeks twice every other week, and then 1x a month for life. ALSO, stop injecting your dog in subcutaneous tissue; this is an intramuscular injection, and there have been NO studies done by adequan that you get the same effect if you inject your dog in the fatty tissue. There are no studies that prove injecting adequan 1x a month adds any additional benefits. I hope this helps some of you, and when used correctly, this product does work for dogs who do not have severe cartilage deterioration. This product helped my dog's acute injury, and I no longer hear any crepitus when she gets up. I Will put her on another repeat 8 dose section in a couple of months as recommended by the manufacturers.


Rated 5 out of 5 stars
Verified Purchase
By Sandie on Jan 16, 2025

Better price than my Vet can do.

Our almost three year old Golden has hip dysplasia. He does underwater treadmill and laser therapy every two weeks. We had gave him a series of Adequan around

Our almost three year old Golden has hip dysplasia. He does underwater treadmill and laser therapy every two weeks. We had gave him a series of Adequan around 6 months ago but felt he needed a series again. He has had 3 injections to date and 5 more to go this round. I can see a difference after three shots. If they are needed every six months to help him, that is what we'll do.